activity 'cliff' base
activity 'cliff' top
kv 1.3 inhibitor
histone deacetylase-10 inhibitor (hdac-10)
mmp-10 inhibitor (matrix metalloproteinase-10)
caspase-10 inhibitor
adam-10 inhibitor (adamalysin, mdc)
histone deacetylase-10 inhibitor (hdac-10)
mmp-10 inhibitor (matrix metalloproteinase-10)
gpr-103 antagonist (g-protein receptor)
gpcr-109a agonist (g-protein coupled, niacin-109a)
gpcr-109a agonist (g-protein coupled, niacin-109a)
gpcr-109a modulator (g-protein-coupled)
niacin-109a receptor agonist
mmp-11 inhibitor (matrix metalloproteinase-11)
histone deacetylase-11 inhibitor (hdac-11)
histone deacetylase-11 inhibitor (hdac-11)
mmp-11 inhibitor (matrix metalloproteinase-11)
p2y-11 receptor agonist (purine metabromic)
c-kit inhibitor (cd 117, tyrosine kinase)
gpr-119 agonist (g-protein coupled receptor)
11b-hsd-1 inhibitor (11b-hydroxysteroid dehydrogenase-1)
11b-hsd-1 inhibitor (11b-hydroxysteroid dehydrogenase-1)
cytochrome p450 inhibitor (cyp-11b1, corticosterone synthase)
cytochrome p450 inhibitor (cyp-11b2, aldosterone synthase)
mmp-12 inhibitor (matrix metalloproteinase-12)
carbonic anhydrase-12 inhibitor
mmp-12 inhibitor (matrix metalloproteinase-12)
12-lipoxygenase inhibitor
gpcr-120 agonist (g-protein coupled receptor)
anti-neoplastic (leukemia l-1210)
mmp-13 inhibitor (matrix metalloproteinase-13)
interleukin-13 blocker (il-13)
interleukin-13 blocker (il-13)
mmp-13 inhibitor (matrix metalloproteinase-13)
gpcr-139 agonist (g-protein coupled receptor)
mmp-14 inhibitor (matrix metalloproteinase-14)
steroid 14-a-demethylase inhibitor
lanosterol-14-a-demethylase inhibitor
carbonic anhydrase-14 inhibitor
caspase-14 inhibitor
mmp-14 inhibitor (matrix metalloproteinase-14)
mmp-15 inhibitor (matrix metalloproteinase-15)
15-pgdh inhibitor (15-hydroxyprostaglandin dehydrogenase)
carbonic anhydrase 15 inhibitor
mmp-15 inhibitor (matrix metalloproteinase-15)
15-lipoxygenase inhibitor
15-pgdh inhibitor (15-hydroxyprostaglandin dehydrogenase)
mmp-16 inhibitor (matrix metalloproteinase-16)
mmp-16 inhibitor (matrix metalloproteinase-16)
tumor necrosis factor blocker (tnf-a, tace, adam-17)
cytochrome p450 inhibitor (cyp-17)
mmp-17 inhibitor (matrix metalloproteinase-17)
mmp-17 inhibitor (matrix metalloproteinase-17)
17b-hsd1 inhibitor (17b-hydroxysteroid dehydrogenase-1, ec 1.1.1.62)
17b-hsd2 inhibitor (17b-hydroxysteroid dehydrogenase-2)
17b-hsd1 inhibitor (17b-hydroxysteroid dehydrogenase-1, ec 1.1.1.62)
17b-hsd2 inhibitor (17b-hydroxysteroid dehydrogenase-2)
anti-neoplastic (sarcoma 180)
ai inhibitor (aromatase) (cyp-19)
cpt-1a activator (carnitine palmitoyl transferase)
ghsr-1a antagonist/inverse agonist (ghrelin receptor)
ck-1a enhancer (casein kinase)
cpt-1a inhibitor (carnitine palmitoyl transferase)
dyrk-1a inhibitor (dual-specificity tyrosine kinase)
cytochrome p450 inhibitor (cyp-1a1)
aldh-1a1 inhibitor (aldehyde dehydrogenase)
interleukin-1b converting enzyme inhibitor (il-1b)
interleukin-1b converting enzyme inhibitor (il-1b)
dyrk-1b (dual-specificity tyrosine kinase, mirk)
pank-1b inhibitor (pantothenate kinase)
ptp-1b inhibitor (protein tyrosine phosphatase)
hiv-1ca inhibitor (capsid assembly)
ck-1d inhibitor (casein kinase)
1heh inhibitor (nicotinamide ribose kinase)
1hur inhibitor (ribosylation factor-1)
1nut inhibitor (adenyl transferase)
dpre1 inhibitor (decaprenylphosphoryl-b-d-ribose-2'-epimerase)
mst-1 kinase inhibitor (mammalian sterile-20)
mmp-20 inhibitor (matrix metalloproteinase-20)
20-hete synthase inhibitor (hydroxyeicosatetraenoic acid)
mmp-20 inhibitor (matrix metalloproteinase-20)
ptpn-22 inhibitor (lymphoid tyrosine phosphatase, lyp)
bacterial protein synthesis inhibitor (23s-ribosome)
anti-neoplastic (walker 256)
cdc-25b cell division cycle phosphatase inhibitor
mmp-26 inhibitor (matrix metalloproteinase-26)
mmp-26 inhibitor (matrix metalloproteinase-26)
cytochrome p450 inhibitor (cyp-26a)
hsp-27 inhibitor (heat shock protein)
factor 2a antagonist
protein phosphatase 2a inhibition (pp2a)
glu-n1/2a nmda receptor inhibitor
nmda ligand (glu-n1/2b selective)
cytochrome p450 inhibitor (cyp-2d6 or cyp-2c19)
cytochrome p450 inhibitor (cyp-2c8)
cytochrome p450 inhibitor (cyp-2c9)
cytochrome p450 inhibitor (cyp-2d6)
cytochrome p450 inhibitor (cyp-2d6 or cyp-2c19)
gpcr-30 agonist (g-protein coupled receptor)
gpcr-30 antagonist
pi-3kc inhibitor (phosphoinositide kinase) (vps-34)
gpcr-35 agonist (g-protein-coupled)
glycogen synthase kinase-a inhibitor (gsk-3a)
c3a agonist (complement 3a)
c3a antagonist (complement 3a)
cytochrome p450 inhibitor (cyp-3a4, grapefruit effect)
glycogen synthase kinase-3-beta inhibitor (gsk-3beta)
nvp-3cl inhibitor (neurovirus peptidase)
pi-3ka inhibitor (phosphoinositide kinase alpha)
pi-3kb inhibitor (phosphoinositide kinase beta)
pi-3kc inhibitor (phosphoinositide kinase) (vps-34)
pi-3kd inhibitor (phosphoinositide kinase delta)
pi-3kg inhibitor (phosphoinositide kinase gamma)
4-hppd inhibitor (hydroxyphenyl pyruvate dioxygenase)
udp-galactose-4'-epimerase (ec 5.1.3.2)
gpcr-40 agonist (g-protein coupled receptor, ffa-1)
gpcr-40 antagonist (g-protein coupled receptor, ffa-1)
high volume industrial chem. epa (450,000 kg/yr)
5-alpha reductase-2 inhibitor
5-alpha reductase inhibitor (testosterone)
5-ht serotonin antagonist
5-ht serotonin reuptake inhibitor (ssri)
5-ht serotonin transport inhibitor (sert)
5-ht serotonin uptake inhibitor
5-ht1-a,b,d autoreceptor antagonist
5-ht1a serotonin agonist
5-ht1a serotonin antagonist
5-ht1a serotonin binder
5-ht1b serotonin agonist
5-ht1b serotonin antagonist
5-ht1b serotonin inverse agonist
5-ht1bd serotonin agonist
5-ht1d serotonin agonist
5-ht1d serotonin antagonist
5-ht1f serotonin agonist
5-ht2 serotonin agonist
5-ht2 serotonin antagonist
5-ht2a serotonin agonist
5-ht2a serotonin antagonist
5-ht2b serotonin agonist
5-ht2b serotonin antagonist
5-ht2c serotonin agonist
5-ht2c serotonin antagonist
5-ht3 serotonin agonist
5-ht3 serotonin antagonist
5-ht3 serotonin ligand
5-ht4 serotonin agonist
5-ht4 serotonin antagonist
5-ht5a serotonin antagonist
5-ht6 serotonin agonist
5-ht6 serotonin antagonist
5-ht7 serotonin agonist
5-ht7 serotonin antagonist
5-htp serotonin uptake inhibitor
5-lipoxygenase inhibitor (flap, ec 1.13.11.12)
odcase inhibitor (orotidine 5'-monophosphate decarboxylase, ec 4.1.1.23)
inosine-5'-monophosphate dehydrogenase inhibitor (impdh)
cytochrome p450 inhibitor (cyp-51)
rad-51 inhibitor
anti-neoplastic (l-5178)
gpcr-52 (g-protein coupled receptor)
6-pgdh inhibitor (6-phosphogluconate dehydrogenase)
6-pgdh inhibitor (6-phosphogluconate dehydrogenase)
anti-neoplastic (hl-60 leukemia)
reproductive toxicity (ca prop. 65)
reproductive toxicity (ca prop. 65, female)
reproductive toxicity (ca prop. 65, male)
mu opioid agonist (mor-1 6tm/e11)
hsp-70 inhibitor (heat shock protein)
human enterovirus inhibitor (hev-71/echo)
allene oxide synthase inhibitor (cyp-74)
hsp-78d inhibitor (grp-78 glucose regulated protein)
hsp-78d inhibitor (grp-78 glucose regulated protein)
factor 7a antagonist
7dhcr inhibitor (7-dehydrocholesterol reductase, ec 1.3.1.21)
myd-88 inhibitor (myeloid differentiation protein)
hsp-90 c-terminal inhibitor
hsp-90 inhibitor (heat shock protein)
psd-95/nmda inhibitor
ul-97 kinase inhibitor
a1 adrenergic agonist
adenosine a1 agonist
adenosine a1 antagonist
adenosine a1 binder
adenosine a1 inverse agonist
apo-a1 upregulator
a1a adrenergic antagonist
a1b adrenergic antagonist
a1d adrenergic antagonist
noradrenergic-a2
a2 adrenergic agonist
a2 adrenergic antagonist
adenosine a2 agonist
thromboxane a2 agonist
thromboxane a2 antagonist (txa2)
phospholipase a2 inhibitor (ec 3.1.1.4)
iglu-a2 modulator (ionotropic glutamate)
anti-neoplastic (ovarian a2780r)
purinergic a2a antagonist
adenosine a2a antagonist
adenosine a2a binder
adenosine a2b agonist
adenosine a2b antagonist
adenosine a2b binder
nicotinic acetylcholine antagonist (nachr-a2b2)
calcium channel a2d modulator
a2e production inhibitor
a3 adrenergic antagonist
adenosine a3 agonist
gaba-a3 agonist (gamma amino butyric acid)
adenosine a3 antagonist
nicotinic acetylcholine agonist (nachr a3/b2)
adenosine a3 binder
nicotinic acetylcholine a3b4 antagonist (nachr a3b4)
nicotinic acetylcholine a3b4 antagonist (nachr a3b4)
nicotinic acetylcholine partial agonist (nachr-a4/b2)
leukotriene a4 hydrolase inhibitor
integrin antagonist (a4b1~a4b7)
nicotinic a4b2 agonist
integrin antagonist (a5b1)
integrin antagonist (a5b3)
vitronectin antagonist (a5b3)
anti-apoptosis protein inhibitor (aap)
abca-1 activator (atp-binding cassette transporter)
abcb1 transport inhibitor
abcg2 transport inhibitor
anti-neoplastic (ascites abdominal)
abl protein kinase inhibitor (bcr-abl)
bcr-abl and t315i-mutant kinase inhibitor
abl protein kinase inhibitor (bcr-abl)
anti-abortifacient
abortifacient (anti-gestagen)
abortifacient oxytocic
abortifacient (veterinary)
anti-addictive (substance abuse treatment, anti-craving)
ac inhibitor (acid ceramidase)
acaricide (ticks mites)
acat inhibitor (acetyl-coa-acyltransferase, ec 2.3.1.16)
acc inhibitor (acetyl-coa carboxylase)(ec6.4.1.2)
acc1 inhibitor (acetyl-coa-carboxylase-1, lipid synthesis)
acc2 inhibitor (acetyl coa carboxylase-2, mitochondrial)
agr inhibitor (accessory gene regulator)
ace-2 inhibitor (angiotensin converting)
ace inhibitor (angiotensin-converting enzyme)
ahas inhibitor (acetohydroxyacid synthase)
acetolactate synthase inhibitor (als)
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
n-acetyl-aspartyl-glutamate peptidase inhibitor (naag)
acat inhibitor (acetyl-coa-acyltransferase, ec 2.3.1.16)
acc1 inhibitor (acetyl-coa-carboxylase-1, lipid synthesis)
acc2 inhibitor (acetyl coa carboxylase-2, mitochondrial)
acc inhibitor (acetyl-coa carboxylase)(ec6.4.1.2)
brd ligand (bromodomain acetyl-lysine)
cysk1 inhibitor (pyridoxal phosphate-dependent-o-acetyl sulfhydrylase)
lpx-c inhibitor (zinc-dependent acetylase)
mach4 agonist (muscarinic-4 acetylcholine)
muscarinic acetylcholine-5 agonist (achr-5)
nicotinic acetylcholine-7 agonist (nachr-7)
nicotinic acetylcholine a3b4 antagonist (nachr a3b4)
nicotinic acetylcholine agonist (nachr)
nicotinic acetylcholine agonist (nachr a3/b2)
acetylcholine antagonist
muscarinic-3 acetylcholine antagonist (machr-3)
nicotinic acetylcholine antagonist (nachr)
nicotinic acetylcholine antagonist (nachr-a2b2)
nicotinic-acetylcholine binder, partial agonist (nachr)
nicotinic acetylcholine inhibitor (nachr-7)
nicotinic acetylcholine partial agonist (nachr-a4/b2)
acetylcholine release enhancer
vacht ligand (vesicular acetylcholine transporter)
acetylcholinesterase inhibitor (ache, ec 3.1.1.7)
acetylcholinesterase synthesis inhibitor (ache)
kat3 inhibitor (histone acetyltransferase)
histone acetyltransferase inhibitor (hat)
acetylcholinesterase synthesis inhibitor (ache)
ce inhibitor (carboxyl esterase, low ache & bche)
organophosphate nerve gas reactivator (ache, bche)
acetylcholinesterase inhibitor (ache, ec 3.1.1.7)
muscarinic acetylcholine-5 agonist (achr-5)
essential fatty acid
ribosomal amino acid
amino acid
gaba-4 antagonist (gamma amino butyric acid)
gaba mimetic (gamma amino butyric acid)
gaba-a modulator (gamma amino butyric acid)
gaba-c agonist (gamma amino butyric acid)
20-hete synthase inhibitor (hydroxyeicosatetraenoic acid)
gaba-a3 agonist (gamma amino butyric acid)
vlcfa synthesis inhibitor (very long chain fatty acid)
mur-d ligase inhibitor (glutamic acid)
lpa-1 antagonist (lysophosphatidic acid)
gpba-1 agonist (g-protein-coupled bile acid)
gaba-c antagonist (gamma amino butyric acid)
gaba agonist (gamma amino butyric acid)
gaba-a agonist (gamma amino butyric acid)
gaba reuptake inhibitor (gamma amino butyric acid)
gaba inverse agonist (gamma amino butyric acid)
gaba-b antagonist (gamma amino butyric acid)
gaba-a antagonist (gamma amino butyric acid)
ffa-2 antagonist (free fatty acid-2)(gpr3)
naaa inhibitor (n-acylethanolamine acid amidase)
faah inhibitor (fatty acid amide hydrolase)
lysergic acid antagonist
p-cab (potassium-competitive acid blocker)
ac inhibitor (acid ceramidase)
elovl-6 inhibitor (fatty acid elongase-6, lce, face)
uricosuric (uric acid excretor, gout treatment)
d-amino acid oxidase inhibitor(daao)
exitory amino acid receptor agonist (eaa)
retinoic acid receptor agonist (rar)
retinoic acid receptor antagonist
rar-b2 ligand (retinoic acid receptor b2)
retinoic acid receptor binder
asic blocker (acid sensitive ion channel)
pfkasiii inhibitor (fatty acid synthase)
fas-ii inhibitor (fatty acid synthase)
pteroic acid synthase inhibitor
fasn-te inhibitor (fatty acid synthase-thioesterase)
urat-1 inhibitor (uric acid transport)
eaat-1 inhibitor (excitory amino acid transport-1)
eaat-2 inhibitor (excitory amino acid transport-2)
fatty acid transport inhibitor
huratat-1 inhibitor (human uric acid transporter)
asbt inhibitor (apical sodium-dependent bile acid transporter)
ibat inhibitor (ileal bile acid transporter)
amcase inhibitor (acidic mammalian chitinase, ec 3.2.1.14)
urinary acidifier
gastric acidifier
urinary acidifier (veterinary)
aromatic amino acids (precursor)
anti-bacterial (acinetobacter baumannii gram-)
anti-bacterial (acinetobacter calcoaceticus gram-)
ack1 inhibitor (activated cdc42 associated kinase)
acly inhibitor (atp-citrate lyase)
anti-acne
fab-z inhibitor (b-hydroxacyl-acp-dehydrase)
fab-g inhibitor (b-ketoacyl-acp-reductase)
fab-i inhibitor (enoyl-acp-reductase)
enoyl-acp reductase inhibitor
fab-b/f inhibitor (b-ketoacetyl-acp synthase 1/2)
fab-h inhibitor (b-ketoacetyl acp synthase-3)
acps inhibitor (acyl carrier protein synthase)
acrosin antagonist
acth inhibitor (adrenocorticotropic hormone)
narcotic (short acting)
analgesic (long acting)
anti-actinic keratosis
ethr inhibitor (incr. ethionamide action)
thrombin-activatable fibrinolysis inhibitor (tafia)
activation by halogen bonding
mast cell activation inhibitor
microtox super-active
cns active
active metabolite
anti-neoplastic (active over nci cell panel)
bbb+ actively transported
vitamin d activity
activity 'cliff' base
activity 'cliff' top
acute gastroenteritis treatment
anti-neoplastic (acute lymphoblastic leukemia, all)
anti-neoplastic (acute monocytic leukemia)
anti-neoplastic (acute myelogenous leukemia, aml)
apl treatment (acute promyelocytic leukemia)
fab-d inhibitor (malonyl co-a acyl carrier)
acps inhibitor (acyl carrier protein synthase)
cact inhibitor (carnitine-acylcarnitine transporter)
naaa inhibitor (n-acylethanolamine acid amidase)
dgat-1 inhibitor (diacylglyceride acyltransferase)
acat inhibitor (acetyl-coa-acyltransferase, ec 2.3.1.16)
alzheimer therapy (ad)
adam-10 inhibitor (adamalysin, mdc)
tumor necrosis factor blocker (tnf-a, tace, adam-17)
adam-10 inhibitor (adamalysin, mdc)
adamts-4 inhibitor (aggrecanase-1)
adamts-5 inhibitor
adamts-5 inhibitor (aggrecanase-2)
anti-addictive (alcohol/narcotic antagonist)
anti-addictive (alcohol/narcotic aversion therapy)
anti-addictive (cocaine, opiates, methamphetamine, etc.)
anti-addictive (narcotic antagonist)
anti-addictive (nicotine, smoking cessation)
anti-addictive (substance abuse treatment, anti-craving)
food additive (veterinary)
nad synthetase inhibitor (nicotinamide adenine dinucleotide)
anti-neoplastic (adenocarcinoma)
adenosine a1 agonist
adenosine a1 antagonist
adenosine a1 binder
adenosine a1 inverse agonist
adenosine a2 agonist
adenosine a2a antagonist
adenosine a2a binder
adenosine a2b agonist
adenosine a2b antagonist
adenosine a2b binder
adenosine a3 agonist
adenosine a3 antagonist
adenosine a3 binder
adenosine deaminase inhibitor (ec 3.5.4.4)
adenosine kinase inhibitor (ec 2.7.1.20)
ampk activator (adenosine monophosphate activated kinase)
adenosine monophosphate deaminase (ampda, ec 3.5.4.6)
adenosine receptor binder
sam-dc inhibitor (s-adenosylmethionine decarboxylase)
adenyl cyclase activator (ec 4.6.1.1)
1nut inhibitor (adenyl transferase)
adenylate cyclase inhibitor (ec 4.6.1.1)
adss inhibitor (adenylosuccinate synthetase, ec 6.3.4.4)
adept (antibody directed prodrug therapy)
anti-adhd (attention deficit hyperactivity disorder)
fimh antagonist (fimbrae-mediated bacterial adhesion)
fak inhibitor (focal adhesion kinase)
vcam-1 inhibitor (vascular cell adhesion molecule)
vap-1 inhibitor (vascular adhesion protein)
anoikis (tumor adhesion reducer)
tissue adhesive
adp antagonist
parg inhibitor (poly-adp-ribose glycohydrolase)
poly adp-ribose polymerase-1 inhibitor (parp-1, ec 2.4.2.30)
poly adp-ribose polymerase-2 inhibitor (parp-2)
poly adp ribose polymerase-3 inhibitor (parp-3)
arf-1 inhibitor (adp-ribosylation factor)
artd-8 inhibitor (adp-ribotransferase)
ophthalmic adrenergic
adrenergic
sympathomimetic (adrenergic)
b2 adrenergic agonist
b3 adrenergic agonist
a2 adrenergic agonist
a1 adrenergic agonist
b1 adrenergic agonist (partial)
anti-adrenergic (andrenolytic)
b3 adrenergic antagonist
a1b adrenergic antagonist
b1 adrenergic antagonist
a1d adrenergic antagonist
a3 adrenergic antagonist
a2 adrenergic antagonist
a1a adrenergic antagonist
beta adrenergic antagonist (beta-blocker)
adrenergic inverse agonist
adrenocortical steroid
adrenocortical steroid (salt regulating)
adrenocortical steroid (topical)
acth inhibitor (adrenocorticotropic hormone)
adss inhibitor (adenylosuccinate synthetase, ec 6.3.4.4)
insecticide (mosquito adult)
rage inhibitor (receptor advanced glycation end products)
age inhibitor (advanced glycation end products)
sphingosine-1-phosphate-5 agonist (s1p-5, aequorin)
anti-bacterial (pseudomonas aeruginosa gram-)
thymoleptic (affecting thymus)
anti-arrhythmic (anti-fibrillatory, anti-afib)
prolificate for agc kinases
age inhibitor (advanced glycation end products)
anti-amd (age related macular degeneration)
adamts-4 inhibitor (aggrecanase-1)
adamts-5 inhibitor (aggrecanase-2)
thrombogenic (platelet aggregant)
poly-q anti-aggregant (anti-huntington's)
platelet anti-aggregant (paf)
mutant sod-1 anti-aggregant (superoxide dismutase)
tau fibrilization inhibitor (polymerization, aggregation)
a-synuclein aggregation inhibitor
beta-amyloid peptide polymerization/aggregation inhibitor
anti-aggressive
cell aging inhibitor
agr inhibitor (accessory gene regulator)
agranulocytosic
anti-agranulocytosic
fungicide (agricultural)
anti-bacterial (francisella tularensis, bio-warfare agt.)
ahas inhibitor (acetohydroxyacid synthase)
aryl hydrocarbon hydroxylase inhibitor (ahh)
ahr agonist (aryl hydrocarbon receptor)
ahr antagonist (aryl hydrocarbon receptor)
ai inhibitor (aromatase) (cyp-19)
aicar transformylase inhibitor
integrin antagonist (aiibb3)
akr1c3 inhibitor (aldo-keto reductase)
protein kinase b inhibitor (akt)
protein kinase b inhibitor (akt-1)
protein kinase b inhibitor (akt-2)
protein kinase b inhibitor (akt-3)
ddl inhibitor (d-alanine-d-alanine ligase)
ddl inhibitor (d-alanine-d-alanine ligase)
aminopeptidase inhibitor (alanyl and/or leucine)
anti-fungal (candida albicans)
alcohol denaturant
anti-addictive (alcohol/narcotic antagonist)
anti-addictive (alcohol/narcotic aversion therapy)
nafld treatment (non-alcoholic fatty liver disease)
aldh-2 inhibitor (aldehyde dehydrogenase)
aldh-1a1 inhibitor (aldehyde dehydrogenase)
aldh-1 inhibitor (aldose reductase, ec 1.1.1.21)
aldh-1a1 inhibitor (aldehyde dehydrogenase)
aldh-2 inhibitor (aldehyde dehydrogenase)
aldh-3 inhibitor (aldose reductase)
akr1c3 inhibitor (aldo-keto reductase)
dihydroneopterin aldolase inhibitor
aldh-3 inhibitor (aldose reductase)
aldh-1 inhibitor (aldose reductase, ec 1.1.1.21)
mineralocorticoid (aldosterone) antagonist
cytochrome p450 inhibitor (cyp-11b2, aldosterone synthase)
raas inhibitor (renin-angiotensin-aldosterone system)
aldrin epoxidation inhibitor
marine toxin/metabolite (algal/sponge/fish)
algicide
alk-2 inhibitor
alk inhibition (anaplastic lymphoma kinase)
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
alkaline phosphatase inducer
alkaline phosphatase inhibitor (ec 3.1.3.1)
alkalizing agent
alkaloid-like (marine/animal)
alkaloid-like (plant/fungal)
dna alkylator
alkyltransferase inhibitor
anti-neoplastic (acute lymphoblastic leukemia, all)
allene oxide synthase inhibitor (cyp-74)
anti-allergic
allergic rhinitis treatment
allosteric hemoglobin effector
allosteric inhibitor (nam)
pam (positive allosteric modifier)
pgf2a allosteric modulator (prostaglandin-f2a)
anti-alopecia (hair restorer)
anti-viral (neurotropic, alpha)
pi-3ka inhibitor (phosphoinositide kinase alpha)
fr-a inhibitor (folate receptor-alpha)
alpha-glucosidase inhibitor (ec 3.2.1.20)
5-alpha reductase-2 inhibitor
5-alpha reductase inhibitor (testosterone)
alpha retinoid x agonist (rxr)
alpha retinoid x antagonist
acetolactate synthase inhibitor (als)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
alzheimer therapy (ad)
amcase inhibitor (acidic mammalian chitinase, ec 3.2.1.14)
anti-amd (age related macular degeneration)
anti-amebic (anti-amoebic)
anti-amebic (entamoeba histolytica)
amebicide (intestinal)
mutagen (ames test carcinogen suspect)
ames test negative (non-mutagenic)
naaa inhibitor (n-acylethanolamine acid amidase)
faah inhibitor (fatty acid amide hydrolase)
ribosomal amino acid
amino acid
d-amino acid oxidase inhibitor(daao)
exitory amino acid receptor agonist (eaa)
eaat-1 inhibitor (excitory amino acid transport-1)
eaat-2 inhibitor (excitory amino acid transport-2)
aromatic amino acids (precursor)
gaba-4 antagonist (gamma amino butyric acid)
gaba mimetic (gamma amino butyric acid)
gaba-a modulator (gamma amino butyric acid)
gaba-c agonist (gamma amino butyric acid)
gaba-a3 agonist (gamma amino butyric acid)
gaba-c antagonist (gamma amino butyric acid)
gaba agonist (gamma amino butyric acid)
gaba-a agonist (gamma amino butyric acid)
gaba reuptake inhibitor (gamma amino butyric acid)
gaba inverse agonist (gamma amino butyric acid)
gaba-b antagonist (gamma amino butyric acid)
gaba-a antagonist (gamma amino butyric acid)
ssao inhibitor (semicarbazide-sensitive amino oxidase, ec 1.4.3.6)
aph3'-iiia inhibitor (aminoglycoside modifying enzyme)
metap-2 inhibitor (methionine aminopeptidase)
metap-1 inhibitor (methionine aminopeptidase)
irap inhibitor (insulin-regulated aminopeptidase)
erap-1 inhibitor (endoplasmic reticulum aminopeptidase)
erap-2 inhibitor (endoplasmic reticulum aminopeptidase)
aminopeptidase inhibitor
aminopeptidase inhibitor (alanyl and/or leucine)
kat-2 inhibitor (kynurenine aminotransferase, ec 2.6.1.7)
anti-neoplastic (acute myelogenous leukemia, aml)
hypoammoniuric (anti-ammoniuric)
anti-amebic (anti-amoebic)
cyclic amp inhibitor (camp)
cyclic amp phosphodiesterase inhibitor (camp)
ampa agonist
ampa antagonist
adenosine monophosphate deaminase (ampda, ec 3.5.4.6)
ampk activator (adenosine monophosphate activated kinase)
ark-5 inhibitor (ampk-related kinase)
beta-amyloid imaging
beta-amyloid peptide polymerization/aggregation inhibitor
beta-amyloid production inhibitor
diagnostic aid: amyloidosis
amyloidosis treatment (ttr, sodi, or p53)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
increased bone formation (anabolic)
anabolic (myotrophic)
anabolic (veterinary)
analeptic (stimulant)
analgesic
analgesic (anti-nociceptive)
analgesic (dental)
analgesic (inhalation)
analgesic (kappa selective)
analgesic (long acting)
analgesic (short duration)
analgesic (ulcer)
analgesic (urinary)
analgesic (veterinary)
enkephalin analog
anandamide uptake inhibitor
anti-anaphylactic
anaplasmodastat (veterinary)
alk inhibition (anaplastic lymphoma kinase)
ancient flavoring
anti-adrenergic (andrenolytic)
androgen antagonist (anti-androgen)
androgen agonist
androgen antagonist (anti-androgen)
anti-androgen (bf3 site)
anti-androgen (dna binding site)
sarm (selective androgen modulator)
mnk/ar degrader (mitogen-activated kinase & androgen receptor)
car agonist (constituitive androstane receptor)
anti-anemic
folate deficiency (anti-anemic)
anesthesia reverser
anesthetic
sedative (pre-anesthetic)
anesthetic (general)
anesthetic (inhalation)
anesthetic (intravenous)
anesthetic (local)
anesthetic (neuralgia)
anesthetic (ophthalmic)
anesthetic (oral)
anesthetic (spinal)
anesthetic (topical)
anesthetic (transport of fish)
anesthetic (veterinary)
anti-anginal
anti-angiogenic
angiogenic
raas inhibitor (renin-angiotensin-aldosterone system)
ace-2 inhibitor (angiotensin converting)
ace inhibitor (angiotensin-converting enzyme)
angiotensin-i antagonist
angiotensin i binder
angiotensin ii agonist
angiotensin ii antagonist
angiotensin ii binder
carbonic anhydrase-1 activator
carbonic anhydrase-1 inhibitor
carbonic anhydrase-12 inhibitor
carbonic anhydrase-14 inhibitor
carbonic anhydrase 15 inhibitor
carbonic anhydrase-2 activator
carbonic anhydrase-2 inhibitor
carbonic anhydrase-4 activator
carbonic anhydrase-4 inhibitor
carbonic anhydrase-5 inhibitor
carbonic anhydrase-6 inhibitor
carbonic anhydrase-7 inhibitor
carbonic anhydrase-9 inhibitor (membrane-assoc., ec 4.2.1.1)
carbonic anhydrase-beta inhibitor (b-ca, ec 4.2.1.1)
teratogen (animal)
alkaloid-like (marine/animal)
anti-oxidant (animal feed)
animal growth promoter
half-life in animal/plasma
anion transport inhibitor
oatp1-b1 inhibitor (organic anion transporting polypeptide)
oatp1-b3 inhibitor (organic anion transporting polypeptide)
oatp2-b1 inhibitor (organic anion transporting polypeptide)
trpa1 agonist (transient receptor potential ankyrin)
trpa1 antagonist (transient receptor potential ankyrin)
annexin binder (lipocortin)
anoikis (tumor adhesion reducer)
anti-anorexic
anorexic (appetite suppressant)
anti-hypoxic (anti-anoxic)
antacid, anti-dyspepsia
anterior pituitary activator
anterior pituitary activator (swine)
anterior pituitary suppressant
anthelmintic (anti-helmintic)
anthelmintic (avian)
anthelmintic (nematode)
anthelmintic (oral)
anthelmintic (veterinary)
dihydrofolate reductase inhibitor (dhfr, bacillus anthracis)
anti-anthrax
anti-bacterial (anthrax lethal factor inhibitor)
anti-abortifacient
anti-acne
anti-actinic keratosis
anti-addictive (alcohol/narcotic antagonist)
anti-addictive (alcohol/narcotic aversion therapy)
anti-addictive (cocaine, opiates, methamphetamine, etc.)
anti-addictive (narcotic antagonist)
anti-addictive (nicotine, smoking cessation)
anti-addictive (substance abuse treatment, anti-craving)
anti-adhd (attention deficit hyperactivity disorder)
anti-adrenergic (andrenolytic)
anti-arrhythmic (anti-fibrillatory, anti-afib)
poly-q anti-aggregant (anti-huntington's)
platelet anti-aggregant (paf)
mutant sod-1 anti-aggregant (superoxide dismutase)
anti-aggressive
anti-agranulocytosic
anti-allergic
anti-alopecia (hair restorer)
anti-amd (age related macular degeneration)
anti-amebic (anti-amoebic)
anti-amebic (entamoeba histolytica)
hypoammoniuric (anti-ammoniuric)
anti-amebic (anti-amoebic)
anti-anaphylactic
androgen antagonist (anti-androgen)
anti-androgen (bf3 site)
anti-androgen (dna binding site)
anti-anemic
folate deficiency (anti-anemic)
anti-anginal
anti-angiogenic
anti-anorexic
anti-hypoxic (anti-anoxic)
anti-anthrax
tranquilizer (anti-anxiety)
anti-apoptosis protein inhibitor (aap)
bcl-2 inhibitor (anti-apoptotic protein)
bcl-xl inhibitor (anti-apoptotic protein)
anti-arrhythmic (anti-fibrillatory, anti-afib)
anti-arrhythmic (ventricular)
anti-arthritic
anti-arthritic prodrug
anti-asthenia (weakness)
anti-asthmatic
anti-asthmatic (local)
anti-atherogenic
anti-atherosclerotic
anti-autistic (social withdrawal)
anti-av-block
anti-bacterial
anti-bacterial (acinetobacter baumannii gram-)
anti-bacterial (acinetobacter calcoaceticus gram-)
anti-bacterial (anthrax lethal factor inhibitor)
anti-bacterial (bacillus subtilis gram+)
anti-bacterial (biofilm forming)
anti-bacterial (clostridium difficle gram+)
anti-bacterial (conjunctivitis)
anti-bacterial (dental plaque)
anti-bacterial (edwardsiella tarda gram+)
anti-bacterial (enterococcus casselflavus gram-, vancomycin resistant)
anti-bacterial (enterococcus faecalis gram+)
anti-bacterial (escherichia coli gram-)
anti-bacterial (francisella tularensis, bio-warfare agt.)
anti-bacterial (gonococcus)
anti-bacterial (gram-)
anti-bacterial (gram+)
anti-bacterial (haemophilus influenzae gram-)
anti-bacterial (helicobacter pylori gram-)
anti-bacterial (intestinal)
anti-bacterial (klebsiella pneumoniae gram-)
anti-bacterial (micrococcus aureus gram+)
anti-bacterial (moraxella catarrhalis gram-)
anti-bacterial (mycobacteria)
anti-bacterial (mycobacterium avium gram+)
anti-bacterial (mycobacterium kansasii gram+)
anti-bacterial (mycobacterium tuberculosis)
anti-bacterial (mycobacterium tuberculosis, mdr)
anti-bacterial (neisseria meningitidis gram-)
anti-bacterial (ophthalmic)
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
anti-bacterial (pseudomonas)
anti-bacterial (pseudomonas aeruginosa gram-)
anti-bacterial (quorum sensing inhibitor)
anti-bacterial (respiratory)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
anti-bacterial (salmonella typhi gram-ve)
anti-bacterial (staphylococcus aureus gram+)
anti-bacterial (staphylococcus saprophyticus gram+)
anti-bacterial (streptococcus haemolyticus gram+)
anti-bacterial (streptococcus mutans gram+)
anti-bacterial (streptococcus pneumoniae gram+)
anti-bacterial (streptococcus pyogenes gram+)
anti-bacterial synergist (mdr)
anti-bacterial (topical)
anti-bacterial (trachoma)
anti-bacterial (tuberculosis,dormant,non-replicating)
anti-bacterial (urinary)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
anti-bacterial (veterinary)
anti-bacterial (yersinia pestis)
anti-bilharzia
anti-biotic potentiator
tachycardic (anti-bradycardic)
anti-cardiac failure
anti-cataleptic
anti-cataracts (anti-cataractic)
anti-cataracts (anti-cataractic)
anti-neoplastic (anti-cd-3)
anti-cerebral disease/injury/palsy
anti-cerebral edema
anti-cerebral insufficiency
anti-cerebral vascular disease
anti-cholelithogenic
anti-cholesteremic
anti-cholinergic
anti-cholinergic (gastric)
anti-cholinergic (ophthalmic)
anti-clotting (anti-coagulant)
anti-cns injury
anti-clotting (anti-coagulant)
anti-convulsant (anti-epileptic)
anti-copd (chronic obstructive pulmonary disease)
anti-addictive (substance abuse treatment, anti-craving)
anti-depressant
anti-diabetic
anti-diabetic neuropathy
anti-diabetic (type-2, t2dm)
anti-diarrheal
anti-diuretic (polyuria)
anti-dna viral
anti-dyskinetic
anti-dyskinetic (giles de la tourette's syndrome)
antacid, anti-dyspepsia
anti-eczema
anti-edemic
anti-emetic (anti-nauseant)
anti-enuresis (bed-wetting)
anti-convulsant (anti-epileptic)
anti-estrogen (serm, selective estrogen receptor modulator)
anti-pyretic hypothermic (anti-febric)
anti-arrhythmic (anti-fibrillatory, anti-afib)
anti-fibrinolytic
anti-filovirus ebola/marburg
anti-folate
anti-fouling paint
anti-fungal (anti-mycotic)
anti-fungal (anti-parasitic, fish)
anti-fungal (aspergillus fumigatus)
anti-fungal (aspergillus niger)
anti-fungal (barley mildew)
anti-fungal (botrydiplodia theobrome)
anti-fungal (candida albicans)
anti-fungal (candida glabrata, torulopsis)
anti-fungal (candida krusei)
anti-fungal (candida parapsilosis)
anti-fungal (candida stellaloidea)
anti-fungal (candida tropicalis)
anti-fungal (cryptoformans neoformans)
anti-fungal (epidermophyton floccosum)
anti-fungal (fonsecaea pedrosoi)
anti-fungal (fusarium oxysporum)
anti-fungal (microsporum canis)
anti-fungal (powdery mildew)
anti-fungal (pyricularia oryzae)
anti-fungal (rhizoctonia bataticola)
anti-fungal (saccharomyces cerevisiae)
anti-fungal (sporothrix schenckii)
anti-fungal (trichophyton mentagrophytes)
anti-fungal (trichophyton rubrum)
anti-fungal (trichophyton spp., ringworm, jock-itch)
anti-fungal (wheat rust)
anti-gerd (gastroesophagael reflux)
anti-gerd (gastroesophageal reflux disease)
abortifacient (anti-gestagen)
anti-glaucoma
anti-glomerulonephritis
anti-glucocorticoid
anti-hallucinogen
anthelmintic (anti-helmintic)
anti-hemolytic
capillary protectant (anti-hemorrhagic)
anti-heparin
anti-hepatic disorders (liver)
anti-hepatoxic
anti-perspirant (anti-hidrotic)
anti-histamine (non-sedating)
anti-histaminic
anti-hpv (human papilloma virus)
poly-q anti-aggregant (anti-huntington's)
anti-hypercholesterolemic
anti-hyperlipidemic (hypolipidemic dyslipidemic)
anti-hyperlipoproteinemic
anti-hyperpigmentation
anti-hypertensive
anti-hypertensive (pulmonary, pah)
anti-hyperthyroid
vasoconstrictor (vasopressor, anti-hypotensive)
anti-hypoxic (anti-anoxic)
anti-septic (anti-infective)
anti-inflammatory
gastroprotective (gastric anti-inflammatory)
anti-inflammatory (cytokine suppressing, csaid)
anti-inflammatory non-steroidal (nsaid)
anti-inflammatory (ophthalmic-topical)
anti-inflammatory (respiratory)
anti-inflammatory (topical)
anti-inflammatory (veterinary)
sleep promoter (anti-insomnia)
anti-leukemic
anti-leukemic (lymphoblasts)
anti-malarial
anti-malarial (liver stage)
anti-menopause
anti-metabolite
anti-methemoglobinemic
anti-microbial
anti-microbial topical
anti-microbial (veterinary)
anti-migrane
anti-mitotic (suppresses cell division)
anti-myasthenic
anti-fungal (anti-mycotic)
anti-narcoleptic (eugeroic)
anti-emetic (anti-nauseant)
anti-neoplastic
anti-neoplastic (active over nci cell panel)
anti-neoplastic (acute lymphoblastic leukemia, all)
anti-neoplastic (acute monocytic leukemia)
anti-neoplastic (acute myelogenous leukemia, aml)
anti-neoplastic (adenocarcinoma)
anti-neoplastic (adjuvant)
anti-neoplastic (anti-cd-3)
anti-neoplastic (ascites abdominal)
anti-neoplastic (bladder)
anti-neoplastic (brain cerebral)
anti-neoplastic (breast)
anti-neoplastic (breast, hormone-dependent)
anti-neoplastic (burkitt's b-cell lymphoma)
anti-neoplastic (chemo-induced tumors)
anti-neoplastic (cll chronic lymphocytic leukemia)
anti-neoplastic (cns, neuroblastoma)
anti-neoplastic (colorectal)
anti-neoplastic (epidermal)
anti-neoplastic (erythroleukemia)
anti-neoplastic (esophagus)
anti-neoplastic (fibrosarcoma)
anti-neoplastic (gastro-intestinal, gist)
anti-neoplastic (glioma)
anti-neoplastic (hct colon)
anti-neoplastic (hela cervical uterine endometrial)
anti-neoplastic (hepatic, liver)
anti-neoplastic (hiv lymphoid)
anti-neoplastic (hl-60 leukemia)
anti-neoplastic (jurkat leukemia)
anti-neoplastic (l-5178)
anti-neoplastic (leukemia l-1210)
anti-neoplastic (lung non-small cell, nsclc)
anti-neoplastic (lung small cell)
anti-neoplastic (lymphoma el-4)
anti-neoplastic (mantle cell lymphoma)
anti-neoplastic mb (medulloblastoma)
anti-neoplastic (melanoma)
anti-neoplastic (multiple myeloma)
anti-neoplastic (myeloma myelogenous)
anti-neoplastic (nasopharynx)
anti-neoplastic (non-hodgkin lymphoma)
anti-neoplastic (osteosarcoma, bone)
anti-neoplastic (ovarian)
anti-neoplastic (ovarian a2780r)
anti-neoplastic (p388 leukemia)
anti-neoplastic (pancreatic)
anti-neoplastic, peritoneal
anti-neoplastic (placlitaxel/mdr resistant)
anti-neoplastic (plasmocytoma)
anti-neoplastic (pleural mesothelioma)
anti-neoplastic (potentiator)
anti-neoplastic (prostate)
anti-neoplastic (ptcl, peripheral t-cell lymphoma)
anti-neoplastic (renal / kidney)
anti-neoplastic (sarcoma 180)
anti-neoplastic (skin basal cell bcc)
anti-neoplastic (solid tumors)
anti-neoplastic (squamous)
anti-neoplastic (taxane refractory)
anti-neoplastic (teratocarcinoma)
anti-neoplastic (testicular)
anti-neoplastic (thyroid)
anti-neoplastic (topical)
anti-neoplastic (walker 256)
anti-nephritic
anti-neuralgic
anti-neuritic
anti-neutropenia (lack of neutrophils)
analgesic (anti-nociceptive)
anti-obesity
anti-occlusion peripheral arteries
anti-osteomylitic
anti-osteoporitic
anti-oxidant
ophthalmic (anti-oxidant)
anti-oxidant (animal feed)
anti-oxidant (food)
anti-oxidant (lipid)
anti-paget's disease
anti-parasitic
anti-fungal (anti-parasitic, fish)
anti-parasitic (topical)
anti-parkinsonian
anti-peristaltic
anti-perspirant (anti-hidrotic)
anti-plaque
anti-plasmodial (berghei)
anti-plasmodial (chabaudi)
anti-plasmodial (falciparum)
anti-plasmodial (falciparum chloroquine resistant)
anti-plasmodial (plasmodium cynomolgi)
anti-plasmodial (veterinary)
anti-plasmodial (yoelii)
anti-plasmodium (vivax)
anti-pneumocystic carinii
anti-prion (tse, cjd, scrapie, misfolded protein)
anti-prolactin
anti-proliferative
anti-prostatic hypertrophy
anti-protozoal
anti-protozoal (babesia)
anti-protozoal (coccidia)
anti-protozoal (cryptosporidium parvum/ hominis)
anti-protozoal (giardia)
anti-protozoal (histomonas)
anti-protozoal (leishmaniasis)
anti-protozoal (toxoplasma gondii)
anti-protozoal (trichomonas)
anti-protozoal (trypanosoma)
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
anti-protozoal (veterinary)
anti-pruritic (keratolytic)
anti-pruritic (topical)
anti-psoriatic (keratolytic)
anti-psychotic (neuroleptic)
anti-pyretic hypothermic (anti-febric)
anti-retinopathic
anti-retroviral
anti-rheumatic
anti-rheumatoid arthritis
anti-rickettsial
anti-schistosomal (flukicide)
anti-schizophrenic
anti-sclerotic
anti-scorbutic
anti-seborrheic
gastric anti-secretory
anti-septic (anti-infective)
anti-septic (intestinal)
anti-septic (oral)
anti-septic shock
anti-septic (topical)
anti-septic (urinary)
anti-silicosis
anti-spasmodic
anti-spasmodic (gall bladder)
anti-spasmodic (gastric)
anti-spasmodic (respiratory)
anti-spasmodic (veterinary)
anti-spermatogenic
anti-syphilitic
anti-thrombotic
anti-tussive
anti-tyrosinaemia
anti-ulcer
anti-ulcerative colitis
anti-upper intestinal disorders
anti-urolithic
anti-vascular disorders
anti-venous disorders
anti-vertigo
anti-viral
anti-viral (bvdv, hcp)
anti-viral (cmv, herpes-2 cytomegalo)
anti-viral (coxsackie)
anti-viral (flavivirus, dengue, west nile)
anti-viral (hepatitis)
anti-viral (hepatitis c, hcv)
anti-viral (herpes genitalis)
anti-viral (hiv)
anti-viral (hiv, attachment/ entry inhibitor)
anti-viral (hiv, reverse transcriptase)
anti-viral (hiv, tat)
anti-viral (hsv-1 herpes simplex)
anti-viral (hsv-1 & hsv-2)
anti-viral (human rhinovirus)
anti-viral (influenza)
anti-viral measles (paramyxovirus)
anti-viral (neurotropic, alpha)
anti-viral (ophthalmic)
anti-viral orthopox (vaccinia/cow, smallpox)
anti-viral (polio t1 maheney)
anti-viral (poultry)
rsv anti-viral (respiratory syncytial fusion)
anti-viral (rous sarcoma)
anti-viral (rubella)
anti-viral (sars-corona)
anti-viral (vzv, pox)
anti-viral (warts)
anti-viral (west nile)
anti-wilson's disease
anti-xerophthalmic
anti-xerostomia (dry mouth)
adept (antibody directed prodrug therapy)
cyanide poisoning antidote
curare antidote
arsine poisoning antidote
antidote (detoxicant)
antidote glycol methanol poisoning
hbsag inhibitor (hepatitis-b surface antigen)
lymphocyte/leukocyte function assoc. antigen antagonist (lfa-1)
vla4 antagonist (very late antigen, eosinophil integrin)
prostate specific membrane antigen inhibitor (psma)
tranquilizer (anti-anxiety)
anxiogenic
anxiolytic
anxiolytic (non-sedating)
apc inhibitor (pro-coagulant)
ape-1 inhibitor (apurinic/apyrimidinic endonuclease-1)
aph3'-iiia inhibitor (aminoglycoside modifying enzyme)
insecticide (aphid)
asbt inhibitor (apical sodium-dependent bile acid transporter)
apkc modulator (atypical protein kinase)
apl treatment (acute promyelocytic leukemia)
apo-a1 upregulator
apo-induced hyperactivity inhibitor
autophagy inducer (non-apoptosis)
apoptosis inducer
caspase-activated apoptosis inducer
apoptosis inhibitor
bacterial apoptosis promoter (pcd)
xiap antagonist (x-linked inhibitor apoptosis protein)
anti-apoptosis protein inhibitor (aap)
ask-1 inhibitor (apoptosis-regulating kinase)
bcl-2 inhibitor (anti-apoptotic protein)
bcl-xl inhibitor (anti-apoptotic protein)
appetite stimulant (orexigenic)
appetite stimulant (veterinary)
anorexic (appetite suppressant)
ape-1 inhibitor (apurinic/apyrimidinic endonuclease-1)
ape-1 inhibitor (apurinic/apyrimidinic endonuclease-1)
mnk/ar degrader (mitogen-activated kinase & androgen receptor)
arachnicide (spiders)
arf-1 inhibitor (adp-ribosylation factor)
arginase ii inhibitor
pad inhibitor (protein arginine deaminase)
prmt-1 inhibitor (protein arginine methyl-transferase)
carm-1 inhibitor (coactivator-assoc. arginine transferase)
ark-5 inhibitor (ampk-related kinase)
insecticide (spodoptura eridania, southern army worm)
ai inhibitor (aromatase) (cyp-19)
aromatic amino acids (precursor)
sahr modulator (selective aromatic hydrocarbon receptor)
cell arrest at g2/m phase
sphingosine-1-phosphate agonist-1 (s1p-1, b-arrestin)
dopamine-2 agonist, b-arrestin biased
b-arrestin signaling recruiter
anti-arrhythmic (anti-fibrillatory, anti-afib)
anti-arrhythmic (ventricular)
arsine poisoning antidote
artd-8 inhibitor (adp-ribotransferase)
anti-occlusion peripheral arteries
anti-arthritic
anti-arthritic prodrug
anti-rheumatoid arthritis
arthropod repellant
artificial rum flavoring
aryl esterase-a
aryl esterase-b
aryl hydrocarbon hydrolase inducer
aryl hydrocarbon hydroxylase inhibitor (ahh)
ahr antagonist (aryl hydrocarbon receptor)
ahr agonist (aryl hydrocarbon receptor)
b-aryl-sulfotransferase-4 inhibitor (bast-4)
asatricide
asbt inhibitor (apical sodium-dependent bile acid transporter)
anti-neoplastic (ascites abdominal)
atp-ase inhibitor (incl. vacuolar, v-atp-ase)
guanosine triphosphatase inhibitor (gtp-ase)
rac-1 inhibitor (rho-gtp-ase)
atp-ase inhibitor (incl. vacuolar, v-atp-ase)
asic blocker (acid sensitive ion channel)
ask-1 inhibitor (apoptosis-regulating kinase)
nmda agonist (n-methyl-d-aspartate)
nmda blocker (n-methyl-d-aspartate)
nmda antagonist (n-methyl-d-aspartate)
nmda antagonist (n-methyl-d-aspartate, competitive)
n-acetyl-aspartyl-glutamate peptidase inhibitor (naag)
aspartyl protease inhibitor (bace-2)
anti-fungal (aspergillus fumigatus)
anti-fungal (aspergillus niger)
telomerase inhibitor human (trap assay)
assay of atp
hiv-1ca inhibitor (capsid assembly)
bv-ca inhibitor (hepatitis b viral capsid assembly)
lipoprotein assembly inhibitor
lymphocyte/leukocyte function assoc. antigen antagonist (lfa-1)
carm-1 inhibitor (coactivator-assoc. arginine transferase)
carbonic anhydrase-9 inhibitor (membrane-assoc., ec 4.2.1.1)
fto inhibitor (fatty mass & obesity assoc. protein)
cenp-e inhibitor (centromere-assoc. protein-e)(kinase-7)
irak-4 inhibitor (interleukin receptor associated kinase)
ack1 inhibitor (activated cdc42 associated kinase)
gak inhibitor (cyclin-g associated kinase)
anti-asthenia (weakness)
anti-asthmatic
anti-asthmatic (local)
astringent
cell arrest at g2/m phase
atr inhibitor (ataxia rad-related)
atr inhibitor (ataxia telangiectasia rad3 related)
friedreich's ataxia treatment
anti-atherogenic
anti-atherosclerotic
dermatitis suppressant (herpetiformis or atopic)
assay of atp
atp-ase inhibitor (incl. vacuolar, v-atp-ase)
atp-ase inhibitor (incl. vacuolar, v-atp-ase)
abca-1 activator (atp-binding cassette transporter)
potassium atp channel opener (sarcolemmal)
acly inhibitor (atp-citrate lyase)
atp-prt inhibitor (atp phosphoribosyl transferase)
atp-prt inhibitor (atp phosphoribosyl transferase)
atp synthase inhibitor
dead-box atpase ddx3
atr inhibitor (ataxia rad-related)
atr inhibitor (ataxia telangiectasia rad3 related)
ikur inhibitor (potassium ion current, atrium)
muscle atrophy treatment
exhibits atropisomerism
anti-viral (hiv, attachment/ entry inhibitor)
anti-adhd (attention deficit hyperactivity disorder)
no attenuated mimic (nitric oxide)
apkc modulator (atypical protein kinase)
dehydrosqualene synthase inhibitor (crtm, staphylococcus aureus)
anti-bacterial (staphylococcus aureus gram+)
anti-bacterial (micrococcus aureus gram+)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
aurora-a kinase inhibitor
aurora-b kinase inhibitor
aurora-c kinase inhibitor
anti-autistic (social withdrawal)
dopamine auto-receptor agonist
immunomodulator (autoimmune therapy)
autophagy inducer (non-apoptosis)
autophagy inhibitor
5-ht1-a,b,d autoreceptor antagonist
autotaxin inhibitor
synthetic auxin
anti-av-block
integrin antagonist (avb3)
integrin antagonist (avb5)
integrin antagonist (avb6)
anti-addictive (alcohol/narcotic aversion therapy)
chemosterilant (avian)
anthelmintic (avian)
anti-bacterial (mycobacterium avium gram+)
vasopressin v2 antagonist (avpr2)
b-arrestin signaling recruiter
b-aryl-sulfotransferase-4 inhibitor (bast-4)
b-catenin agonist
b-catenin/tcf4 pathway inhibitor
b-glucuronidase inhibitor
b-raf kinase inhibitor (braf)
b-secretase inhibitor (bace-1)
b-tryptase inhibitor
pde-b1/2 inhibitor (phosphodiesterase)
b1 adrenergic agonist (partial)
b1 adrenergic antagonist
oatp1-b1 inhibitor (organic anion transporting polypeptide)
oatp2-b1 inhibitor (organic anion transporting polypeptide)
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
vitamin b1 source
human immunoproteasome inhibitor (b1i selective)
cb2 inverse agonist (cannabinoid b2)
rar-b2 ligand (retinoic acid receptor b2)
nicotinic acetylcholine partial agonist (nachr-a4/b2)
nicotinic acetylcholine agonist (nachr a3/b2)
b2 adrenergic agonist
bradykinin b2 agonist
tgf-b2 inhibitor (transforming growth factor)
rar-b2 ligand (retinoic acid receptor b2)
vitamin b2 therapeutic
bombesin-3 agonist (b3)
b3 adrenergic agonist
b3 adrenergic antagonist
thermogenic-b3-agonist
eph-b3 inhibitor (erythropoietin-producing hepatocarcinoma receptor)
oatp1-b3 inhibitor (organic anion transporting polypeptide)
leukotriene b4 agonist
leukotriene b4 antagonist
eph-b4 inhibitor
leukotriene b4 synthesis inhibitor (ltb4)
anti-protozoal (babesia)
b-secretase inhibitor (bace-1)
aspartyl protease inhibitor (bace-2)
dihydrofolate reductase inhibitor (dhfr, bacillus anthracis)
anti-bacterial (bacillus subtilis gram+)
anti-bacterial
spase-1 inhibitor (signal peptidase bacterial)
anti-bacterial (acinetobacter baumannii gram-)
anti-bacterial (acinetobacter calcoaceticus gram-)
fimh antagonist (fimbrae-mediated bacterial adhesion)
anti-bacterial (anthrax lethal factor inhibitor)
bacterial apoptosis promoter (pcd)
anti-bacterial (bacillus subtilis gram+)
anti-bacterial (biofilm forming)
anti-bacterial (clostridium difficle gram+)
anti-bacterial (conjunctivitis)
anti-bacterial (dental plaque)
anti-bacterial (edwardsiella tarda gram+)
anti-bacterial (enterococcus casselflavus gram-, vancomycin resistant)
anti-bacterial (enterococcus faecalis gram+)
anti-bacterial (escherichia coli gram-)
anti-bacterial (francisella tularensis, bio-warfare agt.)
anti-bacterial (gonococcus)
anti-bacterial (gram-)
anti-bacterial (gram+)
bacterial gyrase inhibitor
anti-bacterial (haemophilus influenzae gram-)
anti-bacterial (helicobacter pylori gram-)
anti-bacterial (intestinal)
anti-bacterial (klebsiella pneumoniae gram-)
anti-bacterial (micrococcus aureus gram+)
anti-bacterial (moraxella catarrhalis gram-)
anti-bacterial (mycobacteria)
anti-bacterial (mycobacterium avium gram+)
anti-bacterial (mycobacterium kansasii gram+)
anti-bacterial (mycobacterium tuberculosis)
anti-bacterial (mycobacterium tuberculosis, mdr)
anti-bacterial (neisseria meningitidis gram-)
anti-bacterial (ophthalmic)
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
bacterial protein synthesis inhibitor (23s-ribosome)
anti-bacterial (pseudomonas)
anti-bacterial (pseudomonas aeruginosa gram-)
anti-bacterial (quorum sensing inhibitor)
anti-bacterial (respiratory)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
anti-bacterial (salmonella typhi gram-ve)
bacterial sliding clamp inhibitor
anti-bacterial (staphylococcus aureus gram+)
anti-bacterial (staphylococcus saprophyticus gram+)
anti-bacterial (streptococcus haemolyticus gram+)
anti-bacterial (streptococcus mutans gram+)
anti-bacterial (streptococcus pneumoniae gram+)
anti-bacterial (streptococcus pyogenes gram+)
anti-bacterial synergist (mdr)
anti-bacterial (topical)
anti-bacterial (trachoma)
mur-a inhibitor (bacterial transferase)
anti-bacterial (tuberculosis,dormant,non-replicating)
anti-bacterial (urinary)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
anti-bacterial (veterinary)
anti-bacterial (yersinia pestis)
bir2 selective (second baculovirus iap repeat)
anti-fungal (barley mildew)
ebi-2 antagonist (epstein-barr virus-induced)
anti-neoplastic (skin basal cell bcc)
activity 'cliff' base
basophil inhibitor
b-aryl-sulfotransferase-4 inhibitor (bast-4)
anti-fungal (rhizoctonia bataticola)
electrolyte for flow battery
anti-bacterial (acinetobacter baumannii gram-)
bax activator
gastrin antagonist (bombesin bb)
blood-brain non-penetrant (relatively bbb-)
blood-brain penetrant (relatively bbb+)
bbb+ actively transported
anti-neoplastic (skin basal cell bcc)
ce inhibitor (carboxyl esterase, low ache & bche)
organophosphate nerve gas reactivator (ache, bche)
bcl-2 inhibitor (anti-apoptotic protein)
bcl-xl inhibitor (anti-apoptotic protein)
abl protein kinase inhibitor (bcr-abl)
bcr-abl and t315i-mutant kinase inhibitor
castor bean poison
anti-enuresis (bed-wetting)
insecticide (bedbugs)
ovarian inhibitor (worker bees)
larvicide (colorado potato beetle)
bph treatment (benign prostatic hyperplasia)
cbr antagonist (central benzodiazepine)
benzodiazepine agonist
bz3 benzodiazepine agonist peripheral (pbr)
bz1 benzodiazepine antagonist
bz2 benzodiazepine antagonist peripheral (pbr)
benzodiazepine binder
bz1 benzodiazepine inverse agonist
anti-plasmodial (berghei)
ikkb-1 inhibitor (i-kappa-kinase-beta)
ikkb-2 inhibitor (i-kappa kinase beta)
pi-3kb inhibitor (phosphoinositide kinase beta)
fr-b inhibitor (folate receptor-beta)
beta adrenergic antagonist (beta-blocker)
beta-amyloid imaging
beta-amyloid peptide polymerization/aggregation inhibitor
beta-amyloid production inhibitor
beta adrenergic antagonist (beta-blocker)
btk inhibitor (bruton's tyrosine kinase, beta cells)
beta galactosidase inhibitor (ec 3.2.1.23)
beta-glucosidase inhibitor
carbonic anhydrase-beta inhibitor (b-ca, ec 4.2.1.1)
glycogen synthase kinase-3-beta inhibitor (gsk-3beta)
beta-lactamase ctxm-a inhibitor
beta lactamase inhibitor (ec 3.5.2.6)
meallo-beta-lactamase inhibitors
beta-lactamase resistant
beta turn mimetic
anti-androgen (bf3 site)
dopamine-2 agonist, b-arrestin biased
gpba-1 agonist (g-protein-coupled bile acid)
asbt inhibitor (apical sodium-dependent bile acid transporter)
ibat inhibitor (ileal bile acid transporter)
hydrocholeretic (bile dilution)
choleretic (cholagogue, bile stimulant)
anti-bilharzia
hepato-biliary regulator
glun2c modulator (glutamate binding)
abca-1 activator (atp-binding cassette transporter)
cbi-e (coactivator binding inhibitor estrogen)
cd4-mhc binding inhibitor (major histocompatability complex)
t-butylbicyclophosphorothionate binding inhibitor (tbps)
cbi-vdr (coactivator binding inhibitor vitamin d)
phencyclidine binding (pcp)
mbt antagonist (methyl-lysine binding protein)
srebp inhibitor (sterol regulatory element binding protein)
pbp2a inhibitor (penicillin-binding protein)
anti-androgen (dna binding site)
anti-bacterial (francisella tularensis, bio-warfare agt.)
biofilm blocker (gram-)
anti-bacterial (biofilm forming)
bioflavonoid
biological buffer
molluscicide (biomphalaria glabrata)
anti-biotic potentiator
biotin carboxylase inhibitor (ec 6.3.4.14)
bipolar treatment (manic depression)
bir2 selective (second baculovirus iap repeat)
bird repellant
fructose-1,6-bisphosphatase inhibitor (fbpase, ec 3.1.3.11)
bitter flavor
bitter flavor masker
anti-neoplastic (bladder)
anti-spasmodic (gall bladder)
urinary incontinence (dysuria, overactive bladder, oab)
bleaching agent (pigment synthesis inhibitor)
anti-av-block
blood-brain non-penetrant (relatively bbb-)
blood-brain penetrant activated
blood-brain penetrant (relatively bbb+)
blood stem cell mobilization agent
blood substitute
mediates uptake blood to liver (hepatocytes)
blue food coloring
bmp-2 stimulator (bone morphogenic protein)
bmp-6 inhibitor (bone morphogenic protein)
boron neutron capture therapy (bnct)
bombesin-3 agonist (b3)
bombesin antagonist
gastrin antagonist (bombesin bb)
activation by halogen bonding
anti-neoplastic (osteosarcoma, bone)
bone calcium regulator
increased bone formation (anabolic)
bone loss inhibitor (dental)
bmp-2 stimulator (bone morphogenic protein)
bmp-6 inhibitor (bone morphogenic protein)
bone resorption (osteoclast) inhibitor
bonta inhibitor (botulinum neurotoxin-a)
larvicide (rice borer)
larvicide (hylemya platura, seed corn borer)
boron neutron capture therapy (bnct)
anti-fungal (botrydiplodia theobrome)
bonta inhibitor (botulinum neurotoxin-a)
ibd treatment (irritable bowel disease) crohn's
dead-box atpase ddx3
bph treatment (benign prostatic hyperplasia)
tachycardic (anti-bradycardic)
bradycardic (reduce pulse rate)
bradykinin-1 antagonist
bradykinin 2 antagonist
bradykinin b2 agonist
b-raf kinase inhibitor (braf)
anti-neoplastic (brain cerebral)
brain imaging
blood-brain non-penetrant (relatively bbb-)
blood-brain penetrant activated
blood-brain penetrant (relatively bbb+)
brandy flavoring
brd-2 inhibitor (bromodomain)
brd-3 inhibitor (bromodomain)
brd-4 inhibitor (bromodomain)
brd-9 inhibitor (bromodomain)
brd ligand (bromodomain acetyl-lysine)
anti-neoplastic (breast)
tnbc treatment (triple-negative breast cancer)
anti-neoplastic (breast, hormone-dependent)
brd-2 inhibitor (bromodomain)
brd-4 inhibitor (bromodomain)
brd-3 inhibitor (bromodomain)
brd-9 inhibitor (bromodomain)
brd ligand (bromodomain acetyl-lysine)
bronchodilator
bronchographic
bronchospasmolytic
btk inhibitor (bruton's tyrosine kinase, beta cells)
btk inhibitor (bruton's tyrosine kinase, beta cells)
biological buffer
anti-neoplastic (burkitt's b-cell lymphoma)
t-butylbicyclophosphorothionate binding inhibitor (tbps)
gaba-4 antagonist (gamma amino butyric acid)
gaba mimetic (gamma amino butyric acid)
gaba-a modulator (gamma amino butyric acid)
gaba-c agonist (gamma amino butyric acid)
gaba-a3 agonist (gamma amino butyric acid)
gaba-c antagonist (gamma amino butyric acid)
gaba agonist (gamma amino butyric acid)
gaba-a agonist (gamma amino butyric acid)
gaba reuptake inhibitor (gamma amino butyric acid)
gaba inverse agonist (gamma amino butyric acid)
gaba-b antagonist (gamma amino butyric acid)
gaba-a antagonist (gamma amino butyric acid)
butyryl cholinesterase inhibitor
bv-ca inhibitor (hepatitis b viral capsid assembly)
anti-viral (bvdv, hcp)
bz1 benzodiazepine antagonist
bz1 benzodiazepine inverse agonist
bz2 benzodiazepine antagonist peripheral (pbr)
bz3 benzodiazepine agonist peripheral (pbr)
c-kit inhibitor (cd 117, tyrosine kinase)
c-myc-max heterodimer disruptor
c-raf kinase inhibitor
c-src kinase inhibitor
c-src tyrosine kinase inhibitor
mtor c1/c2 inhibitor (mamalian target of rapamycin)
protein kinase-c1 modulator
mtor c1/c2 inhibitor (mamalian target of rapamycin)
c3a agonist (complement 3a)
c3a antagonist (complement 3a)
leukotriene c4 antagonist
complement c5a antagonist
kca1.1 potassium channel opener (ca and voltage gated)
carbonic anhydrase-beta inhibitor (b-ca, ec 4.2.1.1)
bv-ca inhibitor (hepatitis b viral capsid assembly)
reproductive toxicity (ca prop. 65)
reproductive toxicity (ca prop. 65, female)
reproductive toxicity (ca prop. 65, male)
p-cab (potassium-competitive acid blocker)
cact inhibitor (carnitine-acylcarnitine transporter)
carcinogen cal.prop.65 or isscan
calcium-sensing receptor antagonist (csr, calcilytic)
calcineurin inhibitor
cgrp antagonist (calcitonin gene-related peptide)
ncx reverse inhibitor (sodium/calcium)
ikca calcium activated potassium channel blocker
calcium agonist
camk-2 inhibitor (calcium/calmodulin dependent)
calcium channel a2d modulator
calcium channel activator
l-type calcium channel blocker
t-type calcium channel blocker
calcium channel blocker (l-type)
n-type voltage gated calcium channel blocker (vgcc, vdcc)
cdpk-1 inhibitor (calcium-dependent protein kinase)
bone calcium regulator
soicr suppressor (store-overloaded-induced calcium release)
calcium selective chelator
calcium-sensing receptor antagonist (csr, calcilytic)
anti-bacterial (acinetobacter calcoaceticus gram-)
calmodulin antagonist
camk-2 inhibitor (calcium/calmodulin dependent)
capn2 inhibitor (calpain-2)
calpain mu (i) inhibitor
camk-2 inhibitor (calcium/calmodulin dependent)
cyclic amp phosphodiesterase inhibitor (camp)
cyclic amp inhibitor (camp)
epac-2 antagonist (exchange protein camp activated)
crpc treatment (castration resistant prostate cancer)
tnbc treatment (triple-negative breast cancer)
cancer preventative
pten-deficient cancer treatment
dihydrofolate reductase inhibitor (dhfr, candida)
anti-fungal (candida albicans)
anti-fungal (candida glabrata, torulopsis)
anti-fungal (candida krusei)
anti-fungal (candida parapsilosis)
anti-fungal (candida stellaloidea)
anti-fungal (candida tropicalis)
anti-fungal (microsporum canis)
cannabimimetic
ecb (endogenous cannabinoid)
cb2 inverse agonist (cannabinoid b2)
cannabinoid cb1 agonist
cannabinoid cb1 antagonist
cannabinoid cb1 binder
cannabinoid cb1 inverse agonist
cannabinoid cb2 agonist
cannabinoid cb2 antagonist
cannabinoid cb2 binder
cannabinoid cb2 inverse agonist
cap-dependent m-rna translation inhibitor
capillary protectant (anti-hemorrhagic)
capn2 inhibitor (calpain-2)
hiv-1ca inhibitor (capsid assembly)
bv-ca inhibitor (hepatitis b viral capsid assembly)
boron neutron capture therapy (bnct)
car agonist (constituitive androstane receptor)
carbonic anhydrase-1 activator
carbonic anhydrase-1 inhibitor
carbonic anhydrase-12 inhibitor
carbonic anhydrase-14 inhibitor
carbonic anhydrase 15 inhibitor
carbonic anhydrase-2 activator
carbonic anhydrase-2 inhibitor
carbonic anhydrase-4 activator
carbonic anhydrase-4 inhibitor
carbonic anhydrase-5 inhibitor
carbonic anhydrase-6 inhibitor
carbonic anhydrase-7 inhibitor
carbonic anhydrase-9 inhibitor (membrane-assoc., ec 4.2.1.1)
carbonic anhydrase-beta inhibitor (b-ca, ec 4.2.1.1)
chcr-1 inhibitor (chinese hamster carbonyl reductase)
phosphoenolpyruvate carboxykinase inhibitor (pepck)
ce inhibitor (carboxyl esterase, low ache & bche)
icmt inhibitor (isoprenylcysteine carboxyl transferase)
acc1 inhibitor (acetyl-coa-carboxylase-1, lipid synthesis)
acc2 inhibitor (acetyl coa carboxylase-2, mitochondrial)
acc inhibitor (acetyl-coa carboxylase)(ec6.4.1.2)
biotin carboxylase inhibitor (ec 6.3.4.14)
carboxypeptidase a inhibitor
carboxypeptidase-b inhibitor
glutamate carboxypeptidase ii inhibitor (gcp-ii)
carcinogen cal.prop.65 or isscan
human carcinogen (iarc)
carcinogen (leukemic)
carcinogen (mouse liver)
carcinogen (rat, mouse)
mutagen (ames test carcinogen suspect)
carcinogenicity tested not positive
respiratory stimulant (cardiac)
ischemic stroke treatment (cardiac/cerebral)
cardiac depressant
anti-cardiac failure
cardiac glycoside
cardiac hypertrophy treatment
cardiac pet imaging (positron emission tomography)
herg channel blocker (increase qt interval, cardiac risk)
cardiac stimulant
cardio-toxin
cardiogenic inducer
cardioprotectant
m2 muscarinic antagonist (cardioselective)
cardiotonic
cardiotoxic and/or neurotoxic
cardiovascular agent
dental caries (prophylactic)
anti-pneumocystic carinii
carm-1 inhibitor (coactivator-assoc. arginine transferase)
carminative (relieves flatulence)
cact inhibitor (carnitine-acylcarnitine transporter)
cpt-1a inhibitor (carnitine palmitoyl transferase)
cpt-1a activator (carnitine palmitoyl transferase)
carotenoid synthesis inhibitor
diagnostic aid: carrier
fab-d inhibitor (malonyl co-a acyl carrier)
acps inhibitor (acyl carrier protein synthase)
chondroprotectant (cartilage)
ck1-inhibitor (casein kinase)
ck-1a enhancer (casein kinase)
ck-1d inhibitor (casein kinase)
ck2 inhibitor (casein kinase)
caspase-1 inhibitor
caspase-10 inhibitor
caspase-14 inhibitor
caspase-3 inhibitor
caspase-4 inhibitor
caspase-5 inhibitor
caspase-6 inhibitor
caspase-7 inhibitor
caspase-8 inhibitor
caspase-9 inhibitor
caspase-activated apoptosis inducer
smac activator mimetic (second mitochondria activator caspases)
anti-bacterial (enterococcus casselflavus gram-, vancomycin resistant)
abca-1 activator (atp-binding cassette transporter)
castor bean poison
crpc treatment (castration resistant prostate cancer)
catacholamine potentiator
anti-cataleptic
anti-cataracts (anti-cataractic)
anti-cataracts (anti-cataractic)
anti-bacterial (moraxella catarrhalis gram-)
mitotic catastrophant
comt inhibitor (catechol-o-methyl-transferase, ec 2.1.1.6)
b-catenin agonist
b-catenin/tcf4 pathway inhibitor
laxative (cathartic, prokinetic)
cathepsin-a inhibitor
cathepsin b & l inhibitor (ec 3.4.22.1)
cathepsin c inhibitor
cathepsin d inhibitor
cathepsin f inhibitor
cathepsin g inhibitor
cathepsin k inhibitor
cathepsin s inhibitor
cannabinoid cb1 agonist
cannabinoid cb1 antagonist
cannabinoid cb1 binder
cannabinoid cb1 inverse agonist
cannabinoid cb2 agonist
cannabinoid cb2 antagonist
cannabinoid cb2 binder
cannabinoid cb2 inverse agonist
cb2 inverse agonist (cannabinoid b2)
cbi-e (coactivator binding inhibitor estrogen)
cbi-vdr (coactivator binding inhibitor vitamin d)
cbl inhibitor (cystathionine-b-lyase)
cbr antagonist (central benzodiazepine)
cholecystokinin antagonist (cck)
cholecystokinin-1 agonist (cck-1, cck-a)
cholecystokinin-1 antagonist (cck-1, cck-a)
cholecystokinin-2 antagonist (cck-2, cck-b)
cholecystokinin-1 agonist (cck-1, cck-a)
cholecystokinin-1 antagonist (cck-1, cck-a)
cholecystokinin-2 antagonist (cck-2, cck-b)
ccr-9 antagonist (chemokine-9)
ccr1 antagonist (chemokine)
ccr2 antagonist (chemokine-2, cxcr2)
ccr3 chemokine-3 antagonist
ccr4 antagonist (chemokine-4)
ccr5 agonist (chemokine 5)
ccr5 antagonist (chemokine-5, immune cell receptor)
ccr8 antagonist (chemokine-8)
ccxr1 antagonist (chemokine-x1)
c-kit inhibitor (cd 117, tyrosine kinase)
anti-neoplastic (anti-cd-3)
clk inhibitor (cd2-like kinase)
cd38 inhibitor
cd4-mhc binding inhibitor (major histocompatability complex)
cdc-25b cell division cycle phosphatase inhibitor
cdc25a inhibitor (phosphatase)
ack1 inhibitor (activated cdc42 associated kinase)
cdc7 kinase inhibitor
cdk-5 inhibitor (cyclin-dependent kinase)
cyclin-dependent kinase-7 inhibitor (cdk-7)
cyclin-dependent kinase-1 inhibitor (cdk1)
cyclin-dependent kinase-2 inhibitor (cdk2)
cyclin-dependent kinase-4 inhibitor (cdk4)
cdk5 inhibitor (cyclin-dependent kinase-5)
cyclin-dependent kinase-9 inhibitor (cdk9)
cdpk-1 inhibitor (calcium-dependent protein kinase)
ce inhibitor (carboxyl esterase, low ache & bche)
celiac treatment (gluten reaction)
anti-neoplastic (lung small cell)
esc differentiation blocker (embryonic stem cell)
hsc transplant enhancer (human stem cell)
psc inducer (pluripotent stem cell)
mast cell activation inhibitor
vcam-1 inhibitor (vascular cell adhesion molecule)
cell aging inhibitor
cell arrest at g2/m phase
anti-neoplastic (skin basal cell bcc)
methuosis inducer (cell death)
ledgf-p75 integrase blocker (lens epithelial-cell derived)
stem cell differentiation director
anti-mitotic (suppresses cell division)
cdc-25b cell division cycle phosphatase inhibitor
th17 inhibitor (t-cell helper)
huvec cell inhibition
stem/progenitor cell inhibitor
itk inhibitor (interleukin-2 inducible t-cell kinase)
mcl-1 inhibitor (myeloid cell leukemia)
anti-neoplastic (burkitt's b-cell lymphoma)
anti-neoplastic (ptcl, peripheral t-cell lymphoma)
anti-neoplastic (mantle cell lymphoma)
jcl inhibitor (jurkat cell lysis)
pancreatic cell manipulator
blood stem cell mobilization agent
anti-neoplastic (lung non-small cell, nsclc)
anti-neoplastic (active over nci cell panel)
t-cell proliferation inhibitor
mesangial cell proliferaton inhibitor (mcp)
ccr5 antagonist (chemokine-5, immune cell receptor)
mock-infected mt4 cell toxicity
sickle cell treatment
inhibitor cell-wall synthesis
low toxicity to mice or fibroblast cells
crth-2 antagonist (t-helper-2 cells)
btk inhibitor (bruton's tyrosine kinase, beta cells)
cenp-e inhibitor (centromere-assoc. protein-e)(kinase-7)
cbr antagonist (central benzodiazepine)
cenp-e inhibitor (centromere-assoc. protein-e)(kinase-7)
penicillin & cephalosporin precursor
ac inhibitor (acid ceramidase)
ceramide synthase inhibitor
anti-neoplastic (brain cerebral)
vasodilator (cerebral)
ischemic stroke treatment (cardiac/cerebral)
cerebral circulation stimulant
anti-cerebral disease/injury/palsy
anti-cerebral edema
anti-cerebral insufficiency
nootropic (cerebral stimulant)
cerebral thrombolytic
anti-cerebral vascular disease
cerebroprotective
anti-fungal (saccharomyces cerevisiae)
cervical relaxant
anti-neoplastic (hela cervical uterine endometrial)
anti-addictive (nicotine, smoking cessation)
cholesterolester transfer protein inhibitor (cetp)
cfms kinase inhibitor
cftr blocker (cystic fibrosis transmembrane conductuctance regulator)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
cfviia inhibitor (coagulation factor viia)
cgmp phosphodiesterase inhibitor
cgrp antagonist (calcitonin gene-related peptide)
anti-plasmodial (chabaudi)
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
cng antagonist (cyclic nucleotide-gated channel)
clc2 activator (chloride channel)
asic blocker (acid sensitive ion channel)
calcium channel a2d modulator
calcium channel activator
potassium channel blocker
sodium channel blocker
l-type calcium channel blocker
ikca calcium activated potassium channel blocker
gardos channel blocker
epithelial sodium channel blocker
t-type calcium channel blocker
ion channel blocker
herg channel blocker (increase qt interval, cardiac risk)
calcium channel blocker (l-type)
n-type voltage gated calcium channel blocker (vgcc, vdcc)
voltage gated sodium channel blocker (vgsc)
potassium channel k-7 modulator/inhibitor (kcnq-2)
sodium channel modulator
kir potassium channel modulator (inwardly rectifying)
k2p potassium channel modulator (twin pore)
ik/sk potassium channel modulators
sodium channel nav1.3 modulator
sodium channel nav1.4 blocker
sodium channel nav1.7 modulator
sodium channel nav1.8 modulator
sodium channel opener
potassium channel opener
kca1.1 potassium channel opener (ca and voltage gated)
potassium atp channel opener (sarcolemmal)
herg channel optimized (qt interval decreased)
a-glucosidase chaperone
pc (pharmacological chaperone)
pilus chaperone blocker (pilicide)
chaperone of protein folding
chcr-1 inhibitor (chinese hamster carbonyl reductase)
chk-1 inhibitor (checkpoint kinase-1)
chk-2 inhibitor (checkpoint kinase-2)
calcium selective chelator
metal chelator
chelator
iron chelator (siderophore)
high volume industrial chem. epa (450,000 kg/yr)
chemical warfare agent
anti-neoplastic (chemo-induced tumors)
ccr1 antagonist (chemokine)
cxcr3 agonist (chemokine)
cxcr7 ligand (chemokine)
ccr2 antagonist (chemokine-2, cxcr2)
ccr3 chemokine-3 antagonist
ccr4 antagonist (chemokine-4)
ccr5 agonist (chemokine 5)
ccr5 antagonist (chemokine-5, immune cell receptor)
ccr8 antagonist (chemokine-8)
ccr-9 antagonist (chemokine-9)
cxcr4 chemokine antagonist
hiv-1 chemokine antagonist
cxcr8 chemokine antagonist
cxcr-3 chemokine (killer) antagonist
ccxr1 antagonist (chemokine-x1)
chemosterilant
chemosterilant (avian)
chf (congestive heart failure) therapy
dihydrofolate reductase inhibitor (dhrf, chicken liver)
chikv inhibitor (chikungunya virus)
chikv inhibitor (chikungunya virus)
chimp-human pharmacokinetics compared
chcr-1 inhibitor (chinese hamster carbonyl reductase)
chitin-synthesis inhibitor
amcase inhibitor (acidic mammalian chitinase, ec 3.2.1.14)
chk-1 inhibitor (checkpoint kinase-1)
chk-2 inhibitor (checkpoint kinase-2)
clc2 activator (chloride channel)
chlorismate synthase inhibitor (ec 4.6.1.4)
anti-plasmodial (falciparum chloroquine resistant)
choleretic (cholagogue, bile stimulant)
cholecystographic
diagnostic aid: cholecystographic
cholecystokinin-1 agonist (cck-1, cck-a)
cholecystokinin-1 antagonist (cck-1, cck-a)
cholecystokinin-2 antagonist (cck-2, cck-b)
cholecystokinin antagonist (cck)
anti-cholelithogenic
cholelitholytic agent (gall stones)
cholera toxin inhibitor
choleretic (cholagogue, bile stimulant)
anti-cholesteremic
cholesterol ester reformation inhibitor
cholesterol esterase inhibitor
cholesterol synthesis inhibitor
cholesterolester transfer protein inhibitor (cetp)
succinyl-choline synergist
ophthalmic cholinergic
anti-cholinergic
cholinergic
anti-cholinergic (gastric)
anti-cholinergic (ophthalmic)
butyryl cholinesterase inhibitor
cholinesterase inhibitor (ec 3.1.1.8)
chondroprotectant (cartilage)
chorismate synthase inhibitor
chronic kidney disease treatment
anti-neoplastic (cll chronic lymphocytic leukemia)
chronic myeloid leukemia (cml) treatment
anti-copd (chronic obstructive pulmonary disease)
negative chronotropic (decrease heart rate)
positive chronotropic (increase heart rate)
familial chylomicronemia treatment
human chymase inhibitor
chymotrypsin protease inhibitor
vulnerary (cicatrizant, wound healer)
circadian period decrease
circadian period increase
cerebral circulation stimulant
diagnostic aid: circulation time
acly inhibitor (atp-citrate lyase)
citrus flavor
anti-prion (tse, cjd, scrapie, misfolded protein)
ck-1a enhancer (casein kinase)
ck-1d inhibitor (casein kinase)
ck1-inhibitor (casein kinase)
protein kinase ck2 inhibitor
ck2 inhibitor (casein kinase)
saluretic (na+, cl- excretion)
bacterial sliding clamp inhibitor
clc2 activator (chloride channel)
rnase-h inhibitor (cleavage)
clk inhibitor (cd2-like kinase)
anti-neoplastic (cll chronic lymphocytic leukemia)
anti-bacterial (clostridium difficle gram+)
anti-clotting (anti-coagulant)
cmet tyrosine kinase inhibitor
chronic myeloid leukemia (cml) treatment
anti-viral (cmv, herpes-2 cytomegalo)
cng antagonist (cyclic nucleotide-gated channel)
respiratory stimulant (cns)
cns active
cns depressant
cns dopamine blocker
anti-cns injury
anti-neoplastic (cns, neuroblastoma)
dopamine agonist (cns presynaptic)
cns stimulant
cns stimulant (veterinary)
cns toxicant
fab-d inhibitor (malonyl co-a acyl carrier)
enzyme co-factor
acat inhibitor (acetyl-coa-acyltransferase, ec 2.3.1.16)
acc1 inhibitor (acetyl-coa-carboxylase-1, lipid synthesis)
acc2 inhibitor (acetyl coa carboxylase-2, mitochondrial)
acc inhibitor (acetyl-coa carboxylase)(ec6.4.1.2)
mcd inhibitor (malonyl-coa decarboxylase, ec 4.1.1.9)
scd-1 inhibitor (stearoyl-coa-desaturase)
hmg-coa reductase inhibitor (hmgr, ec 1.1.1.34)
carm-1 inhibitor (coactivator-assoc. arginine transferase)
cbi-e (coactivator binding inhibitor estrogen)
cbi-vdr (coactivator binding inhibitor vitamin d)
thyroid coactivator interaction inhibitor
anti-clotting (anti-coagulant)
apc inhibitor (pro-coagulant)
cfviia inhibitor (coagulation factor viia)
anti-addictive (cocaine, opiates, methamphetamine, etc.)
anti-protozoal (coccidia)
insecticide (cockroach)
cockroach repellant
coenzyme precursor
cognition dysfunction monitor
cognition enhancer
contraceptive (post-coital)
anti-bacterial (escherichia coli gram-)
metap inhibitor (e. coli metalloproteinase)
anti-ulcerative colitis
collagen inhibitor
collagenase inhibitor
anti-neoplastic (hct colon)
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
larvicide (colorado potato beetle)
anti-neoplastic (colorectal)
blue food coloring
in combination therapy
chimp-human pharmacokinetics compared
nmda antagonist (n-methyl-d-aspartate, competitive)
glutamate antagonist (competitive)
p-cab (potassium-competitive acid blocker)
mglur1 antagonist competitive (metabotropic glutamate)
c3a agonist (complement 3a)
c3a antagonist (complement 3a)
complement c5a antagonist
cd4-mhc binding inhibitor (major histocompatability complex)
mitochondrial electron transport complex i inhibitor
mitochondrial electron transport complex ii inhibitor
succinate dehydrogenase (complex ii) inhibitor (ec 1.3.5.1)
mitochondrial electron transport complex iii (qi) inhibitor
mitochondrial electron transport complex iv inhibitor
prrb-prra two-component histidine kinase
ocpd treatment (obsessive compulsive personality)
spect imaging (single photon emission computed tomography)
comt inhibitor (catechol-o-methyl-transferase, ec 2.1.1.6)
melanin concentrating hormone inhibitor (mch-1)
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
cftr blocker (cystic fibrosis transmembrane conductuctance regulator)
chf (congestive heart failure) therapy
ubiquitin conjugation inhibitor (e1/e2)
ubiquitin conjugation inhibitor (e3)
anti-bacterial (conjunctivitis)
car agonist (constituitive androstane receptor)
p97 inhibitor (vcp, valosine containing protein)
contraceptive
contraceptive (female)
contraceptive (male)
contraceptive (post-coital)
smooth muscle contractant
negative inotrope (weakens muscle contraction)
miotic (pupil contraction)
positive inotrope (strengthen muscle contraction)
controlled (soft) deactivation
fertility controller
ace-2 inhibitor (angiotensin converting)
ace inhibitor (angiotensin-converting enzyme)
endothelin converting enzyme inhibitor (ec-1)
interleukin-1b converting enzyme inhibitor (il-1b)
convulsant
anti-convulsant (anti-epileptic)
anti-copd (chronic obstructive pulmonary disease)
larvicide (hylemya platura, seed corn borer)
diagnostic aid: corneal indicator
corneal trauma indicator
anti-viral (sars-corona)
vasodilator (coronary)
luteolytic (corpus luteum)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
ics (inhaled corticosteroid)
corticosteroid (topical)
cytochrome p450 inhibitor (cyp-11b1, corticosterone synthase)
crf receptor antagonist (corticotropin releasing factor)
corticotropin-releasing hormone antagonist
counter-irritant
counter-irritant (topical)
gpcr-35 agonist (g-protein-coupled)
gpcr-109a modulator (g-protein-coupled)
gpba-1 agonist (g-protein-coupled bile acid)
pcft inhibitor (proton-coupled folate transporter)
gpcr-109a agonist (g-protein coupled, niacin-109a)
gpcr119 agonist (g-protein coupled receptor)
tgr-5 agonist (g-protein coupled receptor)
gpcr-30 agonist (g-protein coupled receptor)
gpcr119 antagonist (g-protein coupled receptor)
gpcr-120 agonist (g-protein coupled receptor)
gpcr-139 agonist (g-protein coupled receptor)
gpr-119 agonist (g-protein coupled receptor)
gpcr-52 (g-protein coupled receptor)
gpcr-40 agonist (g-protein coupled receptor, ffa-1)
gpcr-40 antagonist (g-protein coupled receptor, ffa-1)
covalent protein modifier (irreversible)
anti-viral orthopox (vaccinia/cow, smallpox)
cox-1 & cox-2 inhibitor (cyclooxygenase)
cox-2/cox-1 inhibition ratio
cox-1 inhibitor (cyclooxygenase, human)
cox-2/cox-1 inhibition ratio
cox-1 & cox-2 inhibitor (cyclooxygenase)
cox-2 inhibitor (cyclooxygenase)
cox-3 inhibitor (cyclooxygenase)
anti-viral (coxsackie)
cpp inhibitor (cytolytic protein performin)
cpt-1a activator (carnitine palmitoyl transferase)
cpt-1a inhibitor (carnitine palmitoyl transferase)
anti-addictive (substance abuse treatment, anti-craving)
crf receptor antagonist (corticotropin releasing factor)
ibd treatment (irritable bowel disease) crohn's
crohn's disease treatment
dna interstrand cross linker
crpc treatment (castration resistant prostate cancer)
crth-2 agonist
crth-2 antagonist (t-helper-2 cells)
dehydrosqualene synthase inhibitor (crtm, staphylococcus aureus)
cruzain inhibitor (ec.3.4.22.51)
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
anti-fungal (cryptoformans neoformans)
anti-protozoal (cryptosporidium parvum/ hominis)
anti-inflammatory (cytokine suppressing, csaid)
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
calcium-sensing receptor antagonist (csr, calcilytic)
beta-lactamase ctxm-a inhibitor
curare antidote
ikur inhibitor (potassium ion current, atrium)
cushings disease treatment
fractalkine antagonist (cx3cr1)
cxcr-3 chemokine (killer) antagonist
cxcr1 antagonist
ccr2 antagonist (chemokine-2, cxcr2)
cxcr3 agonist (chemokine)
cxcr4 chemokine antagonist
cxcr7 ligand (chemokine)
cxcr8 chemokine antagonist
cyanide poisoning antidote
cyanobacterium extractant
adenyl cyclase activator (ec 4.6.1.1)
guanyl cyclase activator (ec 4.6.1.2)
glutaminyl cyclase inhibitor (ec 2.3.2.5)
adenylate cyclase inhibitor (ec 4.6.1.1)
guanyl cyclase inhibitor (ec 4.6.1.2)
2,3-oxidosqualene cyclase inhibitor (ec 5.4.99.7)
cdc-25b cell division cycle phosphatase inhibitor
cyclic amp inhibitor (camp)
cyclic amp phosphodiesterase inhibitor (camp)
hcn-1 blocker (hyperpolarization-activated cyclic nucleoside-gated)
hcn-2 blocker (hyperpolarization-activated cyclic nucleoside-gated)
cng antagonist (cyclic nucleotide-gated channel)
cyclical mastalgia treatment
cdk-5 inhibitor (cyclin-dependent kinase)
cyclin-dependent kinase-1 inhibitor (cdk1)
cyclin-dependent kinase-2 inhibitor (cdk2)
cyclin-dependent kinase-4 inhibitor (cdk4)
cdk5 inhibitor (cyclin-dependent kinase-5)
cyclin-dependent kinase-7 inhibitor (cdk-7)
cyclin-dependent kinase-9 inhibitor (cdk9)
gak inhibitor (cyclin-g associated kinase)
cox-3 inhibitor (cyclooxygenase)
cox-1 & cox-2 inhibitor (cyclooxygenase)
cox-2 inhibitor (cyclooxygenase)
cox-1 inhibitor (cyclooxygenase, human)
cyclophilin inhibitor
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
anti-plasmodial (plasmodium cynomolgi)
cytochrome p450 inhibitor (cyp-11b1, corticosterone synthase)
cytochrome p450 inhibitor (cyp-11b2, aldosterone synthase)
cytochrome p450 inhibitor (cyp-17)
ai inhibitor (aromatase) (cyp-19)
cytochrome p450 inhibitor (cyp-1a1)
cytochrome p450 inhibitor (cyp-26a)
cytochrome p450 inhibitor (cyp-2d6 or cyp-2c19)
cytochrome p450 inhibitor (cyp-2c8)
cytochrome p450 inhibitor (cyp-2c9)
cytochrome p450 inhibitor (cyp-2d6)
cytochrome p450 inhibitor (cyp-2d6 or cyp-2c19)
cytochrome p450 inhibitor (cyp-3a4, grapefruit effect)
cytochrome p450 inhibitor (cyp-51)
allene oxide synthase inhibitor (cyp-74)
cytochrome p450 inhibitor (cyp1b1)(pah activator)
cytochrome p450 inhibitor (cyp2w1)
cysteinyl leukotriene antagonist (cys-lt1)
cysk1 inhibitor (pyridoxal phosphate-dependent-o-acetyl sulfhydrylase)
cbl inhibitor (cystathionine-b-lyase)
cysteine protease inhibitor
cysteinyl leukotriene antagonist
cysteinyl leukotriene antagonist (cys-lt1)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
cftr blocker (cystic fibrosis transmembrane conductuctance regulator)
cystic fibrosis treatment
diagnostic aid: cystoscopy
cytidine deaminase
cytochrome c inhibitor
cytochrome p450 inducer (drug interaction?)
cytochrome p450 inducer (ethoxyresorufin o-deethylase)
cytochrome p450 inhibitor (cyp-11b1, corticosterone synthase)
cytochrome p450 inhibitor (cyp-11b2, aldosterone synthase)
cytochrome p450 inhibitor (cyp-17)
cytochrome p450 inhibitor (cyp-1a1)
cytochrome p450 inhibitor (cyp-26a)
cytochrome p450 inhibitor (cyp-2c8)
cytochrome p450 inhibitor (cyp-2c9)
cytochrome p450 inhibitor (cyp-2d6)
cytochrome p450 inhibitor (cyp-2d6 or cyp-2c19)
cytochrome p450 inhibitor (cyp-3a4, grapefruit effect)
cytochrome p450 inhibitor (cyp-51)
cytochrome p450 inhibitor (cyp1b1)(pah activator)
cytochrome p450 inhibitor (cyp2w1)
cytochrome p450 inhibitor (drug interaction?)
cytochrome p680 photosynthesis inhibitor (hill reaction)
anti-inflammatory (cytokine suppressing, csaid)
cpp inhibitor (cytolytic protein performin)
anti-viral (cmv, herpes-2 cytomegalo)
cytoprotectant
cytotoxic (hypoxia-activated)
d-amino acid oxidase inhibitor(daao)
dopamine d1 agonist
prostaglandin d1 antagonist
dopamine d1 antagonist
dopamine d1 binder
dopamine d1-d5 antagonist
prostaglandin d2 agonist
dopamine d2 agonist
prostaglandin d2 antagonist
dopamine d2 antagonist
dopamine d2 binder
dopamine d2 partial agonist
prostaglandin d2 synthase inhibitor
dopamine d3 agonist
dopamine d3 antagonist
dopamine d3 binder
dopamine d4 agonist
leukotriene d4 antagonist
dopamine d4 antagonist
dopamine d4 binder
dopamine d1-d5 antagonist
sterol d8d7 isomerase binder
d-amino acid oxidase inhibitor(daao)
dagl-a inhibitor (diacylglycerol lipase-a)
dagr agonist (dissociated glucocorticoid receptor)
gene repair of nonsense mutation damage
dopamine transport inhibitor (dat)
sam-dc inhibitor (s-adenosylmethionine decarboxylase)
dck inhibitor (deoxycytidine kinase)
dcx-1 opioid agonist
dcx-2 opioid agonist
ddl inhibitor (d-alanine-d-alanine ligase)
activated by ddn (deazaflavin-dependent nitroreductase)
ddp-9 inhibitor (dipeptidyl peptidase-9)
ddr inhibitor (discoidin domain)
dead-box atpase ddx3
anti-dyskinetic (giles de la tourette's syndrome)
histone deacetylase-1 inhibitor (hdac-1)
histone deacetylase-10 inhibitor (hdac-10)
histone deacetylase-11 inhibitor (hdac-11)
histone deacetylase-2 inhibitor (hdac-2)
histone deacetylase-3 inhibitor (hdac-3)
histone deacetylase-4 inhibitor (hdac-4)
histone deacetylase-5 inhibitor (hdac-5)
histone deacetylase-6 inhibitor (hdac-6)
histone deacetylase-7 inhibitor (hdac-7)
histone deacetylase-8 inhibitor (hdac-8)
histone deacetylase-9 inhibitor (hdac-9)
controlled (soft) deactivation
dead-box atpase ddx3
cytidine deaminase
pad inhibitor (protein arginine deaminase)
adenosine monophosphate deaminase (ampda, ec 3.5.4.6)
adenosine deaminase inhibitor (ec 3.5.4.4)
methuosis inducer (cell death)
dr5 activator (death receptor)
activated by ddn (deazaflavin-dependent nitroreductase)
dpre1 inhibitor (decaprenylphosphoryl-b-d-ribose-2'-epimerase)
sam-dc inhibitor (s-adenosylmethionine decarboxylase)
odcase inhibitor (orotidine 5'-monophosphate decarboxylase, ec 4.1.1.23)
mcd inhibitor (malonyl-coa decarboxylase, ec 4.1.1.9)
dopa decarboxylase inhibitor
decarboxylase inhibitor
histidine decarboxylase inhibitor
ornithine decarboxylase inhibitor (ec 4.1.1.17)
nasal decongestant
circadian period decrease
negative chronotropic (decrease heart rate)
herg channel optimized (qt interval decreased)
cytochrome p450 inducer (ethoxyresorufin o-deethylase)
erod inducer (7-ethoxyresorufin-o-deethylase)
nutrition aid: vitamin b deficiency
folate deficiency (anti-anemic)
pten-deficient cancer treatment
anti-adhd (attention deficit hyperactivity disorder)
defoliant
peptide deformylase inhibitor
anti-amd (age related macular degeneration)
mnk/ar degrader (mitogen-activated kinase & androgen receptor)
ide inhibitor (insulin-degrading enzyme)
sulfur mustard degredation product
fab-z inhibitor (b-hydroxacyl-acp-dehydrase)
7dhcr inhibitor (7-dehydrocholesterol reductase, ec 1.3.1.21)
dpd inhibitor (dihydropyrimidine dehydrogenase)
pfldh inhibitor (p.falciparum lactate dehydrogenase)
aldh-2 inhibitor (aldehyde dehydrogenase)
6-pgdh inhibitor (6-phosphogluconate dehydrogenase)
15-pgdh inhibitor (15-hydroxyprostaglandin dehydrogenase)
g6pd inhibitor (glucose-6-phosphate dehydrogenase)
ldh-a inhibitor (lactate dehydrogenase)
idh-1 inhibitor (isocitrate dehydrogenase)
aldh-1a1 inhibitor (aldehyde dehydrogenase)
11b-hsd-1 inhibitor (11b-hydroxysteroid dehydrogenase-1)
17b-hsd1 inhibitor (17b-hydroxysteroid dehydrogenase-1, ec 1.1.1.62)
17b-hsd2 inhibitor (17b-hydroxysteroid dehydrogenase-2)
succinate dehydrogenase (complex ii) inhibitor (ec 1.3.5.1)
dhodh-pf inhibitor (dihydroorotate dehydrogenase-falciparum)
dhodh-hs inhibitor (dihydroorate dehydrogenase-human)
malate dehydrogenase inhibitor (ec 1.1.1.37)
inosine-5'-monophosphate dehydrogenase inhibitor (impdh)
pyruvate dehydrogenase kinase inhibitor (pdhk)
dehydroquinase ii inhibitor (ec 4.2.1.10)
dehydrosqualene synthase inhibitor (crtm, staphylococcus aureus)
thyroxine deiodinase inhibitor
oxytocin antagonist (tocolytic, delays labor)
delete
pi-3kd inhibitor (phosphoinositide kinase delta)
pde-delta inhibitor (phosphodiesterase)
delta opioid agonist
delta opioid antagonist
jmjd2 inhibitor (jumonji domain histone demethylase)
lsd-1 inhibitor (lysine specific demethylase)
kdm2/7 inhibitor (histone lysine demethylase)
steroid 14-a-demethylase inhibitor
lanosterol-14-a-demethylase inhibitor
alcohol denaturant
dengue 2 ns2b protease inhibitor
anti-viral (flavivirus, dengue, west nile)
denki inhibitor (dual enkephalinase)
ldlr agonist (low-density lipoprotein)
hdl-c high density lipoprotein elevator
analgesic (dental)
bone loss inhibitor (dental)
dental caries (prophylactic)
anti-bacterial (dental plaque)
dck inhibitor (deoxycytidine kinase)
ido inhibitor (indolamine-2,3-deoxygenase, ec 1.13.11.52)
deoxyhypusine hydroxylase inhibitor (ec 1.14.99.29)
dutp inhibitor (deoxyuridine triphosphatase)
dxr inhibitor (deoxyxylulose-phosphate reductoisomerase, ispc)
anti-neoplastic (breast, hormone-dependent)
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
camk-2 inhibitor (calcium/calmodulin dependent)
lpx-c inhibitor (zinc-dependent acetylase)
asbt inhibitor (apical sodium-dependent bile acid transporter)
sodium-dependent glucose transporter-2 inhibitor (sglt2)
cdk-5 inhibitor (cyclin-dependent kinase)
cyclin-dependent kinase-1 inhibitor (cdk1)
cyclin-dependent kinase-2 inhibitor (cdk2)
cyclin-dependent kinase-4 inhibitor (cdk4)
cdk5 inhibitor (cyclin-dependent kinase-5)
cyclin-dependent kinase-7 inhibitor (cdk-7)
cyclin-dependent kinase-9 inhibitor (cdk9)
cap-dependent m-rna translation inhibitor
activated by ddn (deazaflavin-dependent nitroreductase)
cysk1 inhibitor (pyridoxal phosphate-dependent-o-acetyl sulfhydrylase)
dna-pk inhibitor (dna-dependent protein kinase)
cdpk-1 inhibitor (calcium-dependent protein kinase)
recombinant-dependent replication inhibition (rdr)
rdrp inhibitor (rna-dependent,rna-poylmerase, ec 2.7.7.48)
thy-x inhibitor (fdts, flavin-dependent thymidylate synthase)
depigmentor (melanine synthesis inhibitor)
depilatory (epilatory)
cns depressant
cardiac depressant
anti-depressant
bipolar treatment (manic depression)
ledgf-p75 integrase blocker (lens epithelial-cell derived)
platelet-derived growth factor inhibitor (pdgf)
dermatitis suppressant (herpetiformis or atopic)
dermatologic
scd-1 inhibitor (stearoyl-coa-desaturase)
phytoene desaturase inhibitor
designer drug
microtubule destabilizer
detergent
explosive detonator
antidote (detoxicant)
dub inhibitors (deubiquitinating enzymes, pan)
dgat-1 inhibitor (diacylglyceride acyltransferase)
dihydrofolate reductase inhibitor (dhfr, bacillus anthracis)
dihydrofolate reductase inhibitor (dhfr, candida)
dihydrofolate reductase inhibitor (dhfr, ec 1.5.1.3)
r67 dhfr inhibitor (dihydrofolate reductase)
dihydrofolate reductase inhibitor (dhfr, rat liver)
dhodh-hs inhibitor (dihydroorate dehydrogenase-human)
dhodh-pf inhibitor (dihydroorotate dehydrogenase-falciparum)
dhps inhibitor (dihydropteroate synthase)
dihydrofolate reductase inhibitor (dhrf, chicken liver)
anti-diabetic
hyperglycemic (pro-diabetic)
dk treatment (diabetic ketoacidosis)
anti-diabetic neuropathy
anti-diabetic (type-2, t2dm)
dgat-1 inhibitor (diacylglyceride acyltransferase)
diacylglycerol kinase inhibitor (ec 2.7.1.107)
dagl-a inhibitor (diacylglycerol lipase-a)
diagnostic aid
diagnostic aid: amyloidosis
diagnostic aid: carrier
diagnostic aid: cholecystographic
diagnostic aid: circulation time
diagnostic aid: corneal indicator
diagnostic aid: cystoscopy
diagnostic aid: gastric secretion
diagnostic aid: hepatic
diagnostic aid: hepatobiliary function
diagnostic aid: lymphangiography
diagnostic aid: myasthenia gravis
diagnostic aid: obstetrics
diagnostic aid: pancreas
diagnostic aid: pituitary function
diagnostic aid: renal function
diaphoretic (perspiration)
anti-diarrheal
esc differentiation blocker (embryonic stem cell)
stem cell differentiation director
myd-88 inhibitor (myeloid differentiation protein)
idp inhibitor (inhibitor differentiation protein)
anti-bacterial (clostridium difficle gram+)
dpb treatment (diffuse panbronchiolitis)
r67 dhfr inhibitor (dihydrofolate reductase)
dihydrofolate reductase inhibitor (dhfr, bacillus anthracis)
dihydrofolate reductase inhibitor (dhfr, candida)
dihydrofolate reductase inhibitor (dhfr, ec 1.5.1.3)
dihydrofolate reductase inhibitor (dhfr, rat liver)
dihydrofolate reductase inhibitor (dhrf, chicken liver)
dihydroneopterin aldolase inhibitor
dhodh-hs inhibitor (dihydroorate dehydrogenase-human)
dhodh-pf inhibitor (dihydroorotate dehydrogenase-falciparum)
renal dihydropeptidase inhibitor
hppk inhibitor (6-hydroxymethyl-7,8-dihydropetrin kinase)
dhps inhibitor (dihydropteroate synthase)
dpd inhibitor (dihydropyrimidine dehydrogenase)
mydriatic (dilates pupils)
hydrocholeretic (bile dilution)
hiv protease dimerization inhibitor
nad synthetase inhibitor (nicotinamide adenine dinucleotide)
4-hppd inhibitor (hydroxyphenyl pyruvate dioxygenase)
tdo inhibitor (tryptophan-2,3-dioxygenase, ec 1.13.11.11)
dpp2 inhibitor (dipeptidyl peptidase-2)
dipeptidyl peptidase 3 inhibitor
dpp4 inhibitor (dipeptidyl peptidase 4, ec 3.4.14.5)
dpp-8 inhibitor (dipeptidyl peptidase-8)
ddp-9 inhibitor (dipeptidyl peptidase-9)
upps inhibitor (undecaprenyl diphosphate synthase)
farnesyl diphosphate synthetase inhibitor (fpps, ec 2.5.1.10)
stem cell differentiation director
ddr inhibitor (discoidin domain)
discontinued (withdrawn)
treatment of gaucher's disease
anti-paget's disease
anti-cerebral vascular disease
anti-wilson's disease
leprosy treatment (hansen's disease)
anti-gerd (gastroesophageal reflux disease)
nafld treatment (non-alcoholic fatty liver disease)
lsd treatment (lysosomal storage disease)
fd treatment (fabry disease)
anti-copd (chronic obstructive pulmonary disease)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
ibd treatment (irritable bowel disease) crohn's
anti-cerebral disease/injury/palsy
crohn's disease treatment
huntington disease treatment
chronic kidney disease treatment
polycystic kidney disease treatment
meniere's disease treatment
pompe disease treatment
cushings disease treatment
tsd/sd treatment (tay-sachs, sandhoff diseases)
vaginal disinfectant
disinfectant (topical)
dislipidemia treatment
mutant sod-1 anti-aggregant (superoxide dismutase)
sod inhibitor (superoxide dismutase, ec 1.15.1.1)
anti-adhd (attention deficit hyperactivity disorder)
treatment of sex-hormone disorders
anti-venous disorders
anti-vascular disorders
anti-upper intestinal disorders
anti-hepatic disorders (liver)
golgi disruption
vda vascular disruptive agent
protein-protein disruptor
endocrine disruptor
c-myc-max heterodimer disruptor
mdm2-p53 disruptors
dagr agonist (dissociated glucocorticoid receptor)
diuretic
anti-diuretic (polyuria)
diuretic (potassium-sparing)
anti-mitotic (suppresses cell division)
cdc-25b cell division cycle phosphatase inhibitor
dk treatment (diabetic ketoacidosis)
dlk,map3k12 inhibitor (dual leucine zippper kinase)
dna alkylator
poly d(a-t) dna binder
poly d(c-g) dna binder
dna binder (non-intercalating)
anti-androgen (dna binding site)
dna-pk inhibitor (dna-dependent protein kinase)
dna directed rna polymerase inhibitor
dna gyrase inhibitor
dna helicase inhibitor
dna intercaltor
dna interstrand cross linker
hlig-i inhibitor (human dna ligase-i)
dnmt inhibitor (dna methyltransferase)
mgmt inhibitor (methylguanine-dna methyltransferase)
dna minor groove binder
tdp1 inhibitor (tyrosyl-dna phosphodiesterase)
tdp2 inhibitor (tyrosyl-dna-phosphodiesterase-2)
dna photocleaver
dna-pk inhibitor (dna-dependent protein kinase)
dna polymerase inhibitor
dna primase inhibitor
dna synthesis inhibitor
anti-dna viral
dnmt inhibitor (dna methyltransferase)
ddr inhibitor (discoidin domain)
jmjd2 inhibitor (jumonji domain histone demethylase)
nitroxyl donor
nitric oxide donor
h2s donor (hydrogen sulfide releasing)
dopa decarboxylase inhibitor
triple reuptake inhibitor (serotonin, norepinephrine, dopamine)
dopamine-2 agonist, b-arrestin biased
dopamine agonist
dopamine agonist (cns presynaptic)
dopamine antagonist
dopamine auto-receptor agonist
dopamine b-hydroxylase inhibitor
cns dopamine blocker
dopamine d1 agonist
dopamine d1 antagonist
dopamine d1 binder
dopamine d1-d5 antagonist
dopamine d2 agonist
dopamine d2 antagonist
dopamine d2 binder
dopamine d2 partial agonist
dopamine d3 agonist
dopamine d3 antagonist
dopamine d3 binder
dopamine d4 agonist
dopamine d4 antagonist
dopamine d4 binder
ndri inhibitor (norepinephrine dopamine reuptake)
dopamine reuptake inhibitor
dopamine transport inhibitor (dat)
dopamine transporter binder
dopaminergic
dopaminergic (peripheral)
dopaminergic stabilizer
dormant hiv inhibitor
anti-bacterial (tuberculosis,dormant,non-replicating)
hmt-dot1l inhibitor (histone methyl transferase)
serd (estrogen receptor down-regulator)
down's syndrome therapy
prostaglandin dp antagonist (pgd2)
dpb treatment (diffuse panbronchiolitis)
dpd inhibitor (dihydropyrimidine dehydrogenase)
dpp-8 inhibitor (dipeptidyl peptidase-8)
dpp2 inhibitor (dipeptidyl peptidase-2)
dpp4 inhibitor (dipeptidyl peptidase 4, ec 3.4.14.5)
dpre1 inhibitor (decaprenylphosphoryl-b-d-ribose-2'-epimerase)
dr5 activator (death receptor)
poison (hemlock water dropwort)
drought tolerance promoter
prohibited (regulated) drug
designer drug
cytochrome p450 inhibitor (drug interaction?)
cytochrome p450 inducer (drug interaction?)
drug metabolism inhibitor
drug precursor
multi-drug resistance inhibitor/extruder (mdr1, mrp1)
dry eye treatment
anti-xerostomia (dry mouth)
denki inhibitor (dual enkephalinase)
dlk,map3k12 inhibitor (dual leucine zippper kinase)
dyrk-1a inhibitor (dual-specificity tyrosine kinase)
dyrk-1b (dual-specificity tyrosine kinase, mirk)
dub inhibitors (deubiquitinating enzymes, pan)
muscle relaxant (short duration)
analgesic (short duration)
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
dutp inhibitor (deoxyuridine triphosphatase)
dxr inhibitor (deoxyxylulose-phosphate reductoisomerase, ispc)
mitochondrial dye
dyrk-1a inhibitor (dual-specificity tyrosine kinase)
dyrk-1b (dual-specificity tyrosine kinase, mirk)
ed therapy (erectile dysfunction)
fsd therapy (female sexual dysfunction)
cognition dysfunction monitor
anti-dyskinetic
anti-dyskinetic (giles de la tourette's syndrome)
anti-hyperlipidemic (hypolipidemic dyslipidemic)
dysmenorrhea treatment
dyspareunia
antacid, anti-dyspepsia
treatment for muscular dystrophy
urinary incontinence (dysuria, overactive bladder, oab)
metap inhibitor (e. coli metalloproteinase)
prostaglandin e1 agonist
prostaglandin e1 antagonist
ubiquitin conjugation inhibitor (e1/e2)
mu opioid agonist (mor-1 6tm/e11)
ubiquitin conjugation inhibitor (e1/e2)
prostaglandin e2 agonist
prostaglandin e2 antagonist
ovarian e2 secretion inhibitor
mpges-1 inhibitor (microsomal prostaglandin e2 synthase)
ubiquitin conjugation inhibitor (e3)
prostaglandin e3 agonist
prostaglandin e3 antagonist
prostaglandin e4 agonist
prostaglandin e4 antagonist
exitory amino acid receptor agonist (eaa)
eaat-1 inhibitor (excitory amino acid transport-1)
eaat-2 inhibitor (excitory amino acid transport-2)
ebi-2 antagonist (epstein-barr virus-induced)
anti-filovirus ebola/marburg
endothelin converting enzyme inhibitor (ec-1)
aldh-1 inhibitor (aldose reductase, ec 1.1.1.21)
hmg-coa reductase inhibitor (hmgr, ec 1.1.1.34)
malate dehydrogenase inhibitor (ec 1.1.1.37)
17b-hsd1 inhibitor (17b-hydroxysteroid dehydrogenase-1, ec 1.1.1.62)
nqo2 inhibitor (nad quinone oxidoreductase, ec 1.10.99.2)
mpo inhibitor (myeloperoxidase, ec 1.11.2.2)
tdo inhibitor (tryptophan-2,3-dioxygenase, ec 1.13.11.11)
5-lipoxygenase inhibitor (flap, ec 1.13.11.12)
ido inhibitor (indolamine-2,3-deoxygenase, ec 1.13.11.52)
nitric oxide synthase inhibitor (nos, ec 1.14.13.39)
tyrosinase inhibitor (rtk, ec 1.14.18.1)
deoxyhypusine hydroxylase inhibitor (ec 1.14.99.29)
sod inhibitor (superoxide dismutase, ec 1.15.1.1)
7dhcr inhibitor (7-dehydrocholesterol reductase, ec 1.3.1.21)
succinate dehydrogenase (complex ii) inhibitor (ec 1.3.5.1)
mao-b inhibitor (monamine oxidase, ec 1.4.3.4)
mao inhibitor (ec 1.4.3.4)
ssao inhibitor (semicarbazide-sensitive amino oxidase, ec 1.4.3.6)
dihydrofolate reductase inhibitor (dhfr, ec 1.5.1.3)
nqo1 inhibitor (nad quinone oxidoreductase, ec 1.6.99.2)
thioredoxin reductase inhibitor (trxr, ec 1.8.1.9)
phenylethanolamine methyl-transferase inhibitor (pnmt, ec 2.1.1.28)
thymidylate synthetase inhibitor (ec 2.1.1.45)
comt inhibitor (catechol-o-methyl-transferase, ec 2.1.1.6)
acat inhibitor (acetyl-coa-acyltransferase, ec 2.3.1.16)
glutaminyl cyclase inhibitor (ec 2.3.2.5)
glycogen phosphorylase inhibitor (ec 2.4.1.1)
purine nucleoside phosphorylase inhibitor (pnp, ec 2.4.2.1)
poly adp-ribose polymerase-1 inhibitor (parp-1, ec 2.4.2.30)
farnesyl diphosphate synthetase inhibitor (fpps, ec 2.5.1.10)
glutathione-s-transferase inhibitor (gst, ec 2.5.1.18)
kat-2 inhibitor (kynurenine aminotransferase, ec 2.6.1.7)
diacylglycerol kinase inhibitor (ec 2.7.1.107)
adenosine kinase inhibitor (ec 2.7.1.20)
thymidine kinase inhibitor (ec 2.7.1.21)
pgk phosphoglycerate kinase inhibitor (ec 2.7.2.3)
tmk inhibitor (thymidylate kinase, ec 2.7.4.9)
rdrp inhibitor (rna-dependent,rna-poylmerase, ec 2.7.7.48)
phospholipase a2 inhibitor (ec 3.1.1.4)
acetylcholinesterase inhibitor (ache, ec 3.1.1.7)
cholinesterase inhibitor (ec 3.1.1.8)
alkaline phosphatase inhibitor (ec 3.1.3.1)
fructose-1,6-bisphosphatase inhibitor (fbpase, ec 3.1.3.11)
pde inhibitor (phosphodiesterase, ec 3.1.4)
amcase inhibitor (acidic mammalian chitinase, ec 3.2.1.14)
alpha-glucosidase inhibitor (ec 3.2.1.20)
beta galactosidase inhibitor (ec 3.2.1.23)
gcase (glucocerebrosidase reactivator, ec 3.2.1.45)
glucocerebroside inhibitor (ec 3.2.1.45)
dpp4 inhibitor (dipeptidyl peptidase 4, ec 3.4.14.5)
prcp inhibitor (prolylcarboxypeptidase, ec 3.4.16.2)
prep inhibitor (prolyl oligopeptidase, ec 3.4.21.26)
neutrophil elastase inhibitor (ec 3.4.21.37)
cathepsin b & l inhibitor (ec 3.4.22.1)
beta lactamase inhibitor (ec 3.5.2.6)
adenosine deaminase inhibitor (ec 3.5.4.4)
adenosine monophosphate deaminase (ampda, ec 3.5.4.6)
kynurenine hydroxylase inhibitor (ec 3.7.1.3)
ornithine decarboxylase inhibitor (ec 4.1.1.17)
odcase inhibitor (orotidine 5'-monophosphate decarboxylase, ec 4.1.1.23)
mcd inhibitor (malonyl-coa decarboxylase, ec 4.1.1.9)
carbonic anhydrase-9 inhibitor (membrane-assoc., ec 4.2.1.1)
carbonic anhydrase-beta inhibitor (b-ca, ec 4.2.1.1)
dehydroquinase ii inhibitor (ec 4.2.1.10)
adenyl cyclase activator (ec 4.6.1.1)
adenylate cyclase inhibitor (ec 4.6.1.1)
guanyl cyclase activator (ec 4.6.1.2)
guanyl cyclase inhibitor (ec 4.6.1.2)
chlorismate synthase inhibitor (ec 4.6.1.4)
udp-galactose-4'-epimerase (ec 5.1.3.2)
thromboxane synthetase inhibitor (ec 5.3.99.5)
2,3-oxidosqualene cyclase inhibitor (ec 5.4.99.7)
gs inhibitor (glutamine synthase ec 6.3.1.2)
biotin carboxylase inhibitor (ec 6.3.4.14)
adss inhibitor (adenylosuccinate synthetase, ec 6.3.4.4)
cruzain inhibitor (ec.3.4.22.51)
kmo inhibitor (kynurenine-3- monooxygenase)(ec1.14.13.9)
acc inhibitor (acetyl-coa carboxylase)(ec6.4.1.2)
ecb (endogenous cannabinoid)
human enterovirus inhibitor (hev-71/echo)
ectoparasiticide
ectoparasiticide (veterinary)
anti-eczema
ed therapy (erectile dysfunction)
anti-cerebral edema
anti-edemic
anti-bacterial (edwardsiella tarda gram+)
eef2-kinase inhibitor (eukaryotic elongation factor)
eps high (extrapyramidal effect)
eps relatively low (extrapyramidal effect)
cytochrome p450 inhibitor (cyp-3a4, grapefruit effect)
allosteric hemoglobin effector
p-gp efflux high (p-glycoprotein)
p-gp efflux optimized (p-glycoprotein)
efflux pump inhibitor
treatment pleural effusion
eg5 inhibitor (mitotic kinesin)
egfr inhibitor (epidermal growth factor)
eif4e/eif4g protein interaction inhibitor
eif4e inhibitor (eukaryotic initiation factor, hri)
eif4e/eif4g protein interaction inhibitor
pe treatment (premature ejaculation)
anti-neoplastic (lymphoma el-4)
human neutrophil elastase inhibitor
human leukocyte elastase inhibitor
human pancreatic elastase inhibitor
elastase inhibitor
neutrophil elastase inhibitor (ec 3.4.21.37)
electrolyte for flow battery
electrolyte replenisher adjuvant
mitochondrial electron transport complex i inhibitor
mitochondrial electron transport complex ii inhibitor
mitochondrial electron transport complex iii (qi) inhibitor
mitochondrial electron transport complex iv inhibitor
srebp inhibitor (sterol regulatory element binding protein)
hdl-c high density lipoprotein elevator
elimination rate (metabolism excretion)
elovl-6 inhibitor (fatty acid elongase-6, lce, face)
eef2-kinase inhibitor (eukaryotic elongation factor)
elovl-6 inhibitor (fatty acid elongase-6, lce, face)
esc differentiation blocker (embryonic stem cell)
herbicide (pre-emergence)
herbicide (post-emergence)
emetic
anti-emetic (anti-nauseant)
emge (epigenetic modulator gene expression)
spect imaging (single photon emission computed tomography)
pet imaging (positron emission tomography)
cardiac pet imaging (positron emission tomography)
emollient
emphysema treatment
rage inhibitor (receptor advanced glycation end products)
age inhibitor (advanced glycation end products)
endocrine disruptor
endocytosis inhibitor
ecb (endogenous cannabinoid)
anti-neoplastic (hela cervical uterine endometrial)
endometriosis treatment
ape-1 inhibitor (apurinic/apyrimidinic endonuclease-1)
flap endonuclease-1 inhibitor (fen1)
endopeptidase inhibitor
erap-1 inhibitor (endoplasmic reticulum aminopeptidase)
erap-2 inhibitor (endoplasmic reticulum aminopeptidase)
perk inhibitor (endoplasmic reticulum kinase)
endosomal/lysosomal labile iron probe
vegf-3 inhibitor (vascular endothelial)
vegf-2 inhibitor (vascular endothelial g.f., kdr, fr)
endothelial lipase inhibitor
endothelin-a antagonist (et-a)
endothelin-b antagonist (et-b)
endothelin converting enzyme inhibitor (ec-1)
enkephalin analog
denki inhibitor (dual enkephalinase)
enkephalinase inhibitor
enolpyruvateshikamate-3-phosphate synthase inhibitor (epsps)
fab-i inhibitor (enoyl-acp-reductase)
enoyl-acp reductase inhibitor
anti-amebic (entamoeba histolytica)
anti-bacterial (enterococcus casselflavus gram-, vancomycin resistant)
anti-bacterial (enterococcus faecalis gram+)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
human enterovirus inhibitor (hev-71/echo)
anti-enuresis (bed-wetting)
aph3'-iiia inhibitor (aminoglycoside modifying enzyme)
ide inhibitor (insulin-degrading enzyme)
ire-1 inhibitor (inositol-requiring enzyme)
ace inhibitor (angiotensin-converting enzyme)
enzyme co-factor
hepatic enzyme inducer
endothelin converting enzyme inhibitor (ec-1)
interleukin-1b converting enzyme inhibitor (il-1b)
dub inhibitors (deubiquitinating enzymes, pan)
eosinophil inhibitor
vla4 antagonist (very late antigen, eosinophil integrin)
mur-b inhibitor (udp-ep-glu-nac reductase)
high volume industrial chem. epa (450,000 kg/yr)
epac-2 antagonist (exchange protein camp activated)
eph-b3 inhibitor (erythropoietin-producing hepatocarcinoma receptor)
eph-b4 inhibitor
anti-neoplastic (epidermal)
her-2 inhibitor (human epidermal growth)
egfr inhibitor (epidermal growth factor)
anti-fungal (epidermophyton floccosum)
emge (epigenetic modulator gene expression)
depilatory (epilatory)
anti-convulsant (anti-epileptic)
dpre1 inhibitor (decaprenylphosphoryl-b-d-ribose-2'-epimerase)
udp-galactose-4'-epimerase (ec 5.1.3.2)
ledgf-p75 integrase blocker (lens epithelial-cell derived)
epithelial sodium channel blocker
squalene epoxidase inhibitor
aldrin epoxidation inhibitor
epoxide hydrolase inhibitor
eps high (extrapyramidal effect)
eps inducer (extrapyramidal symptoms)
eps relatively low (extrapyramidal effect)
ikke inhibitor (i-kappa-kinase epsilon)
pkc-e inhibitor (protein kinase-c-epsilon)
enolpyruvateshikamate-3-phosphate synthase inhibitor (epsps)
ebi-2 antagonist (epstein-barr virus-induced)
erap-1 inhibitor (endoplasmic reticulum aminopeptidase)
erap-2 inhibitor (endoplasmic reticulum aminopeptidase)
erb-tyrosine kinase inhibitor
ed therapy (erectile dysfunction)
insecticide (spodoptura eridania, southern army worm)
erk-1/erk-2 inhibitor (extracellular signal-regulated kinase)
erk-1/erk-2 inhibitor (extracellular signal-regulated kinase)
erk-5 inhibitor (extracellular signal-regulated kinase, mapk-7)
erod inducer (7-ethoxyresorufin-o-deethylase)
err-a antagonist (estrogen related receptor)
err-a inverse agonist (estrogen-related receptor-a)
sle treatment (systemic lupus erythematous)
nrf-2 activator (nuclear factor erythroid)
anti-neoplastic (erythroleukemia)
eph-b3 inhibitor (erythropoietin-producing hepatocarcinoma receptor)
es treatment (ewing's sarcoma)
esc differentiation blocker (embryonic stem cell)
anti-bacterial (escherichia coli gram-)
treatment of eskape pathogens
anti-neoplastic (esophagus)
fruit essences
essential fatty acid
cholesterol ester reformation inhibitor
aryl esterase-a
aryl esterase-b
cholesterol esterase inhibitor
juvenile hormone esterase inhibitor
neuropathy target esterase inhibitor (nte)
ce inhibitor (carboxyl esterase, low ache & bche)
estrogen
cbi-e (coactivator binding inhibitor estrogen)
estrogen a agonist
estrogen a antagonist
estrogen a receptor binder
estrogen b receptor binder/agonist
serd (estrogen receptor down-regulator)
anti-estrogen (serm, selective estrogen receptor modulator)
err-a antagonist (estrogen related receptor)
err-a inverse agonist (estrogen-related receptor-a)
anti-estrogen (serm, selective estrogen receptor modulator)
estrogenic hrt (hormone replacement therapy)
estrone sulfatase inhibitor
estrus synchronizer
endothelin-a antagonist (et-a)
endothelin-b antagonist (et-b)
anti-addictive (cocaine, opiates, methamphetamine, etc.)
ethr inhibitor (incr. ethionamide action)
cytochrome p450 inducer (ethoxyresorufin o-deethylase)
erod inducer (7-ethoxyresorufin-o-deethylase)
ethr inhibitor (incr. ethionamide action)
ethylene synthesis inhibitor (ripening delayer)
anti-narcoleptic (eugeroic)
eef2-kinase inhibitor (eukaryotic elongation factor)
eif4e inhibitor (eukaryotic initiation factor, hri)
euphoretic
es treatment (ewing's sarcoma)
sodium-hydrogen exchange inhibitor (nhe-1)
epac-2 antagonist (exchange protein camp activated)
eaat-1 inhibitor (excitory amino acid transport-1)
eaat-2 inhibitor (excitory amino acid transport-2)
natriuretic (sodium excretion)
saluretic (na+, cl- excretion)
elimination rate (metabolism excretion)
inhibits excretion of penicillin
uricosuric (uric acid excretor, gout treatment)
exhibits atropisomerism
exitory amino acid receptor agonist (eaa)
expectorant
explosive detonator
emge (epigenetic modulator gene expression)
erk-1/erk-2 inhibitor (extracellular signal-regulated kinase)
erk-5 inhibitor (extracellular signal-regulated kinase, mapk-7)
plant extract
cyanobacterium extractant
eps high (extrapyramidal effect)
eps relatively low (extrapyramidal effect)
eps inducer (extrapyramidal symptoms)
multi-drug resistance inhibitor/extruder (mdr1, mrp1)
dry eye treatment
ezh-2 inhibitor (enhancer zeste homolog)
pgf2a allosteric modulator (prostaglandin-f2a)
prostaglandin f2a agonist
prostaglandin f2a antagonist
faah inhibitor (fatty acid amide hydrolase)
fab-b/f inhibitor (b-ketoacetyl-acp synthase 1/2)
fab-d inhibitor (malonyl co-a acyl carrier)
fab-g inhibitor (b-ketoacyl-acp-reductase)
fab-h inhibitor (b-ketoacetyl acp synthase-3)
fab-i inhibitor (enoyl-acp-reductase)
fab-k inhibitor
fab-z inhibitor (b-hydroxacyl-acp-dehydrase)
fd treatment (fabry disease)
elovl-6 inhibitor (fatty acid elongase-6, lce, face)
treatment facial hirsutism
nutritional factor
enzyme co-factor
crf receptor antagonist (corticotropin releasing factor)
somatostatin antagonist (srif release-inhibiting factor)
hif-1 inhibitor (hypoxia inducible factor)
mif (macrophage migration inhibitory factor)
igf-1 inhibitor (insulin-like growth factor)
eef2-kinase inhibitor (eukaryotic elongation factor)
tgf-b2 inhibitor (transforming growth factor)
arf-1 inhibitor (adp-ribosylation factor)
ngf agonist (nerve growth factor)
hgf inhibitor (hepatocyte growth factor)
egfr inhibitor (epidermal growth factor)
1hur inhibitor (ribosylation factor-1)
factor 2a antagonist
factor 7a antagonist
nerve growth factor activator
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
tumor necrosis factor blocker (tnf-a, tace, adam-17)
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
nrf-2 activator (nuclear factor erythroid)
eif4e inhibitor (eukaryotic initiation factor, hri)
nerve growth factor inhibitor
anti-bacterial (anthrax lethal factor inhibitor)
fibroblast growth factor inhibitor (fgf)
platelet-derived growth factor inhibitor (pdgf)
factor ix-a inhibitor
nuclear factor kappa b inhibitor (nf-k-b)
tissue factor vii-a inhibitor
cfviia inhibitor (coagulation factor viia)
factor x-a antagonist (fxa)
factor xia antagonist (fxia)
anti-bacterial (enterococcus faecalis gram+)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
fak inhibitor (focal adhesion kinase)
falcipain-2 inhibitor
falcipain-3 inhibitor
falcipain inhibitor
anti-plasmodial (falciparum)
dhodh-pf inhibitor (dihydroorotate dehydrogenase-falciparum)
anti-plasmodial (falciparum chloroquine resistant)
familial chylomicronemia treatment
fap inhibitor (fibroblast activator protein)
farnesoid x agonist (fxr)
farnesoid-x antagonist (fxr)
farnesyl diphosphate synthetase inhibitor (fpps, ec 2.5.1.10)
ftase (farnesyl transferase inhibitor)
fas-ii inhibitor (fatty acid synthase)
flukicide (fasciolicide)
fasn-te inhibitor (fatty acid synthase-thioesterase)
essential fatty acid
vlcfa synthesis inhibitor (very long chain fatty acid)
ffa-2 antagonist (free fatty acid-2)(gpr3)
faah inhibitor (fatty acid amide hydrolase)
elovl-6 inhibitor (fatty acid elongase-6, lce, face)
pfkasiii inhibitor (fatty acid synthase)
fas-ii inhibitor (fatty acid synthase)
fasn-te inhibitor (fatty acid synthase-thioesterase)
fatty acid transport inhibitor
nafld treatment (non-alcoholic fatty liver disease)
fto inhibitor (fatty mass & obesity assoc. protein)
fructose-1,6-bisphosphatase inhibitor (fbpase, ec 3.1.3.11)
fd treatment (fabry disease)
thy-x inhibitor (fdts, flavin-dependent thymidylate synthase)
anti-pyretic hypothermic (anti-febric)
anti-oxidant (animal feed)
reproductive toxicity (ca prop. 65, female)
contraceptive (female)
fsd therapy (female sexual dysfunction)
flap endonuclease-1 inhibitor (fen1)
fertility controller
plant fertility regulator
npff ligand (neuropeptide ff)
gpcr-40 agonist (g-protein coupled receptor, ffa-1)
gpcr-40 antagonist (g-protein coupled receptor, ffa-1)
ffa-2 antagonist (free fatty acid-2)(gpr3)
fibroblast growth factor inhibitor (fgf)
tau fibrilization inhibitor (polymerization, aggregation)
anti-arrhythmic (anti-fibrillatory, anti-afib)
fibrinogen antagonist
thrombin-activatable fibrinolysis inhibitor (tafia)
fibrinolytic
anti-fibrinolytic
fap inhibitor (fibroblast activator protein)
low toxicity to mice or fibroblast cells
fibroblast growth factor inhibitor (fgf)
fop (fibrodysplasia ossificans progressiva)
anti-neoplastic (fibrosarcoma)
ipf treatment (ideopathic pulmonary fibrosis)
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
cftr blocker (cystic fibrosis transmembrane conductuctance regulator)
cystic fibrosis treatment
filaricide (worms)
ftsz inhibition (filimentation temp.-sensitive protein z)
anti-filovirus ebola/marburg
gfr tracer (glomerular filtration rate)
fimh antagonist (fimbrae-mediated bacterial adhesion)
fimh antagonist (fimbrae-mediated bacterial adhesion)
marine toxin/metabolite (algal/sponge/fish)
piscicide (fish)
anti-fungal (anti-parasitic, fish)
anesthetic (transport of fish)
perfume fixative
peptidyl prolyl isomerase inhibitor (fkbp)
fkbp51 ligand
5-lipoxygenase inhibitor (flap, ec 1.13.11.12)
flap endonuclease-1 inhibitor (fen1)
carminative (relieves flatulence)
thy-x inhibitor (fdts, flavin-dependent thymidylate synthase)
anti-viral (flavivirus, dengue, west nile)
flavodoxin inhibitor
citrus flavor
bitter flavor
bitter flavor masker
flavoring
imitation grape flavoring
brandy flavoring
artificial rum flavoring
ancient flavoring
insecticide (fleas)
anti-fungal (epidermophyton floccosum)
electrolyte for flow battery
flt-3 inhibitor (tyrosine kinase)
anti-schistosomal (flukicide)
flukicide (fasciolicide)
flukicide (veterinary)
fluorescent label
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
fak inhibitor (focal adhesion kinase)
anti-folate
folate deficiency (anti-anemic)
fr-a inhibitor (folate receptor-alpha)
fr-b inhibitor (folate receptor-beta)
pcft inhibitor (proton-coupled folate transporter)
chaperone of protein folding
fsh agonist (follicle stimulating hormone)
fsh antagonist (follicle stimulating hormone)
anti-fungal (fonsecaea pedrosoi)
anti-oxidant (food)
food additive (veterinary)
blue food coloring
fop (fibrodysplasia ossificans progressiva)
increased bone formation (anabolic)
anti-bacterial (biofilm forming)
garft inhibitor (glycinamide ribonucleotide formyl transferase)
anti-fouling paint
farnesyl diphosphate synthetase inhibitor (fpps, ec 2.5.1.10)
vegf-2 inhibitor (vascular endothelial g.f., kdr, fr)
fr-a inhibitor (folate receptor-alpha)
fr-b inhibitor (folate receptor-beta)
fractalkine antagonist (cx3cr1)
fragile-x syndrome treatment
perfume or fragrance ingredient/intermediate
anti-bacterial (francisella tularensis, bio-warfare agt.)
fraxin/ubiquitin interaction inhibition
ffa-2 antagonist (free fatty acid-2)(gpr3)
free radical generator
free radical scavenger
friedreich's ataxia treatment
sfrp-1 inhibitor (secreted frizzled-related protein)
poison (toad/frog)
frog neurotoxin
fructose-1,6-bisphosphatase inhibitor (fbpase, ec 3.1.3.11)
fruit essences
fruit ripener
fruit & vegetable setting agent
fsd therapy (female sexual dysfunction)
fsh agonist (follicle stimulating hormone)
fsh antagonist (follicle stimulating hormone)
ftase (farnesyl transferase inhibitor)
fto inhibitor (fatty mass & obesity assoc. protein)
ftsz inhibition (filimentation temp.-sensitive protein z)
qfr inhibitor (quinol/fumarate reductase)
fumigant
soil fumigant
anti-fungal (aspergillus fumigatus)
alkaloid-like (plant/fungal)
anti-fungal (anti-mycotic)
anti-fungal (anti-parasitic, fish)
anti-fungal (aspergillus fumigatus)
anti-fungal (aspergillus niger)
anti-fungal (barley mildew)
anti-fungal (botrydiplodia theobrome)
anti-fungal (candida albicans)
anti-fungal (candida glabrata, torulopsis)
anti-fungal (candida krusei)
anti-fungal (candida parapsilosis)
anti-fungal (candida stellaloidea)
anti-fungal (candida tropicalis)
anti-fungal (cryptoformans neoformans)
anti-fungal (epidermophyton floccosum)
anti-fungal (fonsecaea pedrosoi)
anti-fungal (fusarium oxysporum)
anti-fungal (microsporum canis)
anti-fungal (powdery mildew)
anti-fungal (pyricularia oryzae)
anti-fungal (rhizoctonia bataticola)
anti-fungal (saccharomyces cerevisiae)
anti-fungal (sporothrix schenckii)
anti-fungal (trichophyton mentagrophytes)
anti-fungal (trichophyton rubrum)
anti-fungal (trichophyton spp., ringworm, jock-itch)
anti-fungal (wheat rust)
fungicide
fungicide (agricultural)
fungicide (systemic)
fungicide (topical)
fungistat
anti-fungal (fusarium oxysporum)
rsv anti-viral (respiratory syncytial fusion)
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
factor x-a antagonist (fxa)
factor xia antagonist (fxia)
farnesoid x agonist (fxr)
farnesoid-x antagonist (fxr)
g-protein activator
g-secretase inhibitor
g-secretase modulator
vegf-2 inhibitor (vascular endothelial g.f., kdr, fr)
cell arrest at g2/m phase
trmd inhibitor (t-rna-n1-g37 methyltransferase)
gadph binder (glyceraldehyde-3-phosphate, g3dph)
g6pd inhibitor (glucose-6-phosphate dehydrogenase)
lysine methyl-transferase g9a inhibitor
gaba-4 antagonist (gamma amino butyric acid)
gaba-a agonist (gamma amino butyric acid)
gaba-a antagonist (gamma amino butyric acid)
gaba-a modulator (gamma amino butyric acid)
gaba-a3 agonist (gamma amino butyric acid)
gaba agonist (gamma amino butyric acid)
gaba-b agonist
gaba-b antagonist (gamma amino butyric acid)
gaba-c agonist (gamma amino butyric acid)
gaba-c antagonist (gamma amino butyric acid)
gaba inverse agonist (gamma amino butyric acid)
gaba mimetic (gamma amino butyric acid)
gaba reuptake inhibitor (gamma amino butyric acid)
gaba-t inhibitor (gaba transaminase)
gaba-t inhibitor (gaba transaminase)
gadph binder (glyceraldehyde-3-phosphate, g3dph)
gak inhibitor (cyclin-g associated kinase)
gal-3 antagonist (galanin-3)
udp-galactose-4'-epimerase (ec 5.1.3.2)
beta galactosidase inhibitor (ec 3.2.1.23)
galactosyltransferase inhibitor
gal-3 antagonist (galanin-3)
galectin-3 inhibitor
anti-spasmodic (gall bladder)
cholelitholytic agent (gall stones)
pi-3kg inhibitor (phosphoinositide kinase gamma)
rorgt antagonist (nuclear hormone receptor gamma)
gaba-4 antagonist (gamma amino butyric acid)
gaba mimetic (gamma amino butyric acid)
gaba-a modulator (gamma amino butyric acid)
gaba-c agonist (gamma amino butyric acid)
gaba-a3 agonist (gamma amino butyric acid)
gaba-c antagonist (gamma amino butyric acid)
gaba agonist (gamma amino butyric acid)
gaba-a agonist (gamma amino butyric acid)
gaba reuptake inhibitor (gamma amino butyric acid)
gaba inverse agonist (gamma amino butyric acid)
gaba-b antagonist (gamma amino butyric acid)
gaba-a antagonist (gamma amino butyric acid)
ganglionic blocker (ganglioplegic)
ganglionic blocker (ganglioplegic)
gap junction modifier
gardos channel blocker
garft inhibitor (glycinamide ribonucleotide formyl transferase)
nerve gas prophylactic
organophosphate nerve gas reactivator (ache, bche)
lennox-gastaut syndrome treatment
anti-cholinergic (gastric)
anti-spasmodic (gastric)
gastric acidifier
gastroprotective (gastric anti-inflammatory)
gastric anti-secretory
diagnostic aid: gastric secretion
gastrin antagonist (bombesin bb)
anti-neoplastic (gastro-intestinal, gist)
gastroprokinetic (gastro-intestinal stimulant)
acute gastroenteritis treatment
anti-gerd (gastroesophagael reflux)
anti-gerd (gastroesophageal reflux disease)
gastrointestinal toxicant
gastroprokinetic (gastro-intestinal stimulant)
gastroprotective (gastric anti-inflammatory)
treatment of gaucher's disease
gcase (glucocerebrosidase reactivator, ec 3.2.1.45)
glutamate carboxypeptidase ii inhibitor (gcp-ii)
gcs inhibitor (glucosylceramide synthase)
gdept (gene directed prodrug therapy)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
mmp-2 inhibitor (matrix metalloproteinase-2, gelatinase-a)
mmp-9 inhibitor (matrix metalloproteinase-9, gelatinase-b)
gelling agent
smn2 gene activator/modulator
gene delivery vector
gdept (gene directed prodrug therapy)
emge (epigenetic modulator gene expression)
agr inhibitor (accessory gene regulator)
cgrp antagonist (calcitonin gene-related peptide)
gene repair of nonsense mutation damage
inhibitor of gene transcription
anesthetic (general)
free radical generator
intracellular superoxide generator
mrg-x1 antagonist (mas-related genes)
anti-viral (herpes genitalis)
geranylgeranyl transferase inhibitor
anti-gerd (gastroesophagael reflux)
anti-gerd (gastroesophageal reflux disease)
seed germinator
abortifacient (anti-gestagen)
gfr tracer (glomerular filtration rate)
ghrelin agonist (grln, partial)
ghsr-1a antagonist/inverse agonist (ghrelin receptor)
ghsr-1a antagonist/inverse agonist (ghrelin receptor)
anti-protozoal (giardia)
anti-dyskinetic (giles de la tourette's syndrome)
anti-neoplastic (gastro-intestinal, gist)
gkrp modulator (glucokinase regulatory protein)
molluscicide (biomphalaria glabrata)
anti-fungal (candida glabrata, torulopsis)
anti-glaucoma
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
anti-neoplastic (glioma)
gfr tracer (glomerular filtration rate)
anti-glomerulonephritis
glp-1 agonist (glucagon-like peptide)
gls inhibitor (glutaminase)
glu-n1/2a nmda receptor inhibitor
nmda ligand (glu-n1/2b selective)
mur-b inhibitor (udp-ep-glu-nac reductase)
glucagon antagonist
glp-1 agonist (glucagon-like peptide)
glucagon stimulant
1,3-b-d-glucan synthase inhibitor
gcase (glucocerebrosidase reactivator, ec 3.2.1.45)
glucocerebroside inhibitor (ec 3.2.1.45)
anti-glucocorticoid
glucocorticoid (agonist-modulator)
dagr agonist (dissociated glucocorticoid receptor)
sgk-1 inhibitor (serum glucocorticoid-regulated kinase)
glucocorticoid (topical)
glucokinase agonist
gkrp modulator (glucokinase regulatory protein)
glucolipid synthase inhibitor
glucosamine-6-phosphate synthase inhibitor
hepatic glucose-6-phosphatase inhibitor
g6pd inhibitor (glucose-6-phosphate dehydrogenase)
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
hsp-78d inhibitor (grp-78 glucose regulated protein)
glut-1 inhibitor (glucose transport)
sodium-dependent glucose transporter-2 inhibitor (sglt2)
a-glucosidase chaperone
beta-glucosidase inhibitor
alpha-glucosidase inhibitor (ec 3.2.1.20)
gcs inhibitor (glucosylceramide synthase)
b-glucuronidase inhibitor
gluk-1 agonist (glutamate kainate)
gluk-1 antagonist (glutamate kainate)
glun2c/d antagonist (glutamate)
glun2c modulator (glutamate binding)
glur-2 partial agonist (glutamate kainate)
glur5 kainate antagonist
glut-1 inhibitor (glucose transport)
mglur1 imager (metabotropic glutamate)
mglur5 agonist (metabotropic glutamate)
mglur2 agonist (metabotropic glutamate)
mglur3 agonist (metabotropic glutamate)
mglur5 antagonist (metabotropic glutamate)
mglur1 antagonist competitive (metabotropic glutamate)
mglur7 antagonist (meabotropic glutamate)
mglur4 agonist (meabotropic glutamate)
mglur3 antagonist (metabotropic glutamate)
mglur2 modulator (metabotropic glutamate)
glun2c/d antagonist (glutamate)
iglu-a2 modulator (ionotropic glutamate)
iglur-5 binder (ionotropic glutamate-5)
glutamate antagonist
glutamate antagonist (competitive)
glun2c modulator (glutamate binding)
glutamate carboxypeptidase ii inhibitor (gcp-ii)
gluk-1 agonist (glutamate kainate)
gluk-1 antagonist (glutamate kainate)
glur-2 partial agonist (glutamate kainate)
n-acetyl-aspartyl-glutamate peptidase inhibitor (naag)
glutamate racemase (muri)
mglur agonist (metabotropic glutamate receptor)
mglur antagonist (metabotropic glutamate receptor)
glutamatergic
mur-d ligase inhibitor (glutamic acid)
gls inhibitor (glutaminase)
gs inhibitor (glutamine synthase ec 6.3.1.2)
glutaminyl cyclase inhibitor (ec 2.3.2.5)
gsh synthase inducer (glutathione)
glutathione-s-transferase inducer (gst)
glutathione-s-transferase inhibitor (gst, ec 2.5.1.18)
celiac treatment (gluten reaction)
rage inhibitor (receptor advanced glycation end products)
age inhibitor (advanced glycation end products)
gadph binder (glyceraldehyde-3-phosphate, g3dph)
hlda inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlde inhibitor (glycero-manno-heptose-7-phosphate kinase)
garft inhibitor (glycinamide ribonucleotide formyl transferase)
glycine receptor antagonist
glyt-1 inhibitor (glycine transport)
glycogen phosphorylase inhibitor (ec 2.4.1.1)
glycogen synthase kinase-3-beta inhibitor (gsk-3beta)
glycogen synthase kinase-a inhibitor (gsk-3a)
nad glycohydrase inhibitor
parg inhibitor (poly-adp-ribose glycohydrolase)
nad glycohydrolase inhibitor
antidote glycol methanol poisoning
hiv-gp41 inhibitor (glycoprotein)
pgp overexpression inhibitor (plasma membrane glycoprotein)
p-gp efflux high (p-glycoprotein)
p-gp efflux optimized (p-glycoprotein)
p-glycoprotein inhibitor (p-gp)
glycoprotein receptor antagonist
glycosidase inhibitor
cardiac glycoside
glycosuric (veterinary)
glyt-1 inhibitor (glycine transport)
gmp guanosine monophosphate synthase inhibitor
lhrh/gnrh antagonist (luteinizing/gonadotropin-releasing hormone)
golgi disruption
gonad stimulator
lhrh/gnrh antagonist (luteinizing/gonadotropin-releasing hormone)
anti-protozoal (toxoplasma gondii)
anti-bacterial (gonococcus)
uricosuric (uric acid excretor, gout treatment)
p-glycoprotein inhibitor (p-gp)
p-gp efflux high (p-glycoprotein)
p-gp efflux optimized (p-glycoprotein)
gp iib/iiia inhibitor (gycoprotein)
hiv-gp41 inhibitor (glycoprotein)
gpba-1 agonist (g-protein-coupled bile acid)
gpcr-109a agonist (g-protein coupled, niacin-109a)
gpcr-109a modulator (g-protein-coupled)
gpcr-120 agonist (g-protein coupled receptor)
gpcr-139 agonist (g-protein coupled receptor)
gpcr-30 agonist (g-protein coupled receptor)
gpcr-30 antagonist
gpcr-35 agonist (g-protein-coupled)
gpcr-40 agonist (g-protein coupled receptor, ffa-1)
gpcr-40 antagonist (g-protein coupled receptor, ffa-1)
gpcr-52 (g-protein coupled receptor)
gpcr119 agonist (g-protein coupled receptor)
gpcr119 antagonist (g-protein coupled receptor)
gpr-103 antagonist (g-protein receptor)
gpr-119 agonist (g-protein coupled receptor)
ffa-2 antagonist (free fatty acid-2)(gpr3)
imitation grape flavoring
cytochrome p450 inhibitor (cyp-3a4, grapefruit effect)
turf growth regulator (grass)
grass growth inhibitor
diagnostic aid: myasthenia gravis
ghrelin agonist (grln, partial)
dna minor groove binder
her-2 inhibitor (human epidermal growth)
igf-1 inhibitor (insulin-like growth factor)
tgf-b2 inhibitor (transforming growth factor)
ngf agonist (nerve growth factor)
hgf inhibitor (hepatocyte growth factor)
egfr inhibitor (epidermal growth factor)
nerve growth factor activator
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
nerve growth factor inhibitor
fibroblast growth factor inhibitor (fgf)
platelet-derived growth factor inhibitor (pdgf)
growth hormone inhibitor (secretagogue)
growth hormone stimulant
plant growth inhibitor
prostate growth inhibitor
grass growth inhibitor
animal growth promoter
growth regulator
plant growth regulator
insect growth regulator
turf growth regulator (grass)
plant growth stimulant
hsp-78d inhibitor (grp-78 glucose regulated protein)
gs inhibitor (glutamine synthase ec 6.3.1.2)
gsh synthase inducer (glutathione)
glycogen synthase kinase-a inhibitor (gsk-3a)
glycogen synthase kinase-3-beta inhibitor (gsk-3beta)
glutathione-s-transferase inducer (gst)
glutathione-s-transferase inhibitor (gst, ec 2.5.1.18)
guanosine triphosphatase inhibitor (gtp-ase)
rac-1 inhibitor (rho-gtp-ase)
tgt inhibitor (t-rna guanine transglycolase)
gmp guanosine monophosphate synthase inhibitor
guanosine triphosphatase inhibitor (gtp-ase)
guanyl cyclase activator (ec 4.6.1.2)
guanyl cyclase inhibitor (ec 4.6.1.2)
gp iib/iiia inhibitor (gycoprotein)
bacterial gyrase inhibitor
dna gyrase inhibitor
h1 histamine agonist
h1 histamine antagonist
h1 histamine binder
prostaglandin h2 antagonist
h2 histamine agonist
h2 histamine antagonist
h2s donor (hydrogen sulfide releasing)
h3 histamine agonist
h3 histamine antagonist/inverse agonist
h3 histamine binder
h4 histamine agonist
h4 histamine antagonist
h4 histamine ligand
na-h5n1 inhibitor (neuramidase h5n1)
na-h5n1 inhibitor (neuramidase h5n1)
anti-bacterial (streptococcus haemolyticus gram+)
anti-bacterial (haemophilus influenzae gram-)
anti-alopecia (hair restorer)
half-life in animal/plasma
anti-hallucinogen
psychodysleptic (hallucinogenic)
activation by halogen bonding
chcr-1 inhibitor (chinese hamster carbonyl reductase)
leprosy treatment (hansen's disease)
sclerosing agent (hardening)
histone acetyltransferase inhibitor (hat)
hbsag inhibitor (hepatitis-b surface antigen)
hbvp inhibitor (hepatitis-b viral polymerase)
hcn-1 blocker (hyperpolarization-activated cyclic nucleoside-gated)
hcn-2 blocker (hyperpolarization-activated cyclic nucleoside-gated)
anti-viral (bvdv, hcp)
anti-neoplastic (hct colon)
anti-viral (hepatitis c, hcv)
hepatitis c protease inhibitor (hcv)
hepatitis c polymerase inhibitor (hcv)
hcv entry inhibitor (hepatitis-c)
hcv entry inhibitor (hepatitis c)
hcv ires inhibitor (internal ribosome entry site, hepatitis c)
hcv-ns3 protease inhibitor (hepatitis c)
hcv-ns4a inhibitor (hepatitis c)
hcv-ns4b inhibitor (hepatitis c)
hcv-ns5a inhibitor (hepatitis c)
hcv-ns5b rna polymerase inhibitor (hepatitis c)
hcv-p7 inhibitor (hepatitis c)
histone deacetylase-1 inhibitor (hdac-1)
histone deacetylase-10 inhibitor (hdac-10)
histone deacetylase-11 inhibitor (hdac-11)
histone deacetylase-2 inhibitor (hdac-2)
histone deacetylase-3 inhibitor (hdac-3)
histone deacetylase-4 inhibitor (hdac-4)
histone deacetylase-5 inhibitor (hdac-5)
histone deacetylase-6 inhibitor (hdac-6)
histone deacetylase-7 inhibitor (hdac-7)
histone deacetylase-8 inhibitor (hdac-8)
histone deacetylase-9 inhibitor (hdac-9)
hdl-c high density lipoprotein elevator
vulnerary (cicatrizant, wound healer)
chf (congestive heart failure) therapy
positive chronotropic (increase heart rate)
negative chronotropic (decrease heart rate)
hsp-90 inhibitor (heat shock protein)
hsp-70 inhibitor (heat shock protein)
hsp-27 inhibitor (heat shock protein)
nek2/hec1 inhibitor
hedgehog signaling antagonist (hh, smo)
anti-neoplastic (hela cervical uterine endometrial)
viral helicase inhibitor
rna helicase inhibitor
dna helicase inhibitor
anti-bacterial (helicobacter pylori gram-)
anthelmintic (anti-helmintic)
th17 inhibitor (t-cell helper)
crth-2 antagonist (t-helper-2 cells)
hematinic (hemaglobin promoter)
hematinic (hemaglobin promoter)
hematopoietic vitamin
heme oxygenase-1 inhibitor
poison (hemlock)
poison (hemlock water dropwort)
allosteric hemoglobin effector
anti-hemolytic
hemophilia therapy
hemorrhagenic
capillary protectant (anti-hemorrhagic)
hemostatic
hemozoin ligand
anti-heparin
diagnostic aid: hepatic
anti-hepatic disorders (liver)
hepatic enzyme inducer
hepatic glucose-6-phosphatase inhibitor
anti-neoplastic (hepatic, liver)
hepatic steatosis treatment
anti-viral (hepatitis)
svps inhibitor (subviral particle secretion, hepatitis-b)
hbsag inhibitor (hepatitis-b surface antigen)
bv-ca inhibitor (hepatitis b viral capsid assembly)
hbvp inhibitor (hepatitis-b viral polymerase)
hcv entry inhibitor (hepatitis-c)
hcv-ns3 protease inhibitor (hepatitis c)
hcv-ns5b rna polymerase inhibitor (hepatitis c)
hcv ires inhibitor (internal ribosome entry site, hepatitis c)
hcv-ns4b inhibitor (hepatitis c)
hcv-ns5a inhibitor (hepatitis c)
hcv entry inhibitor (hepatitis c)
hcv-p7 inhibitor (hepatitis c)
hcv-ns4a inhibitor (hepatitis c)
anti-viral (hepatitis c, hcv)
hepatitis c polymerase inhibitor (hcv)
hepatitis c protease inhibitor (hcv)
hepato-biliary regulator
diagnostic aid: hepatobiliary function
eph-b3 inhibitor (erythropoietin-producing hepatocarcinoma receptor)
hgf inhibitor (hepatocyte growth factor)
mediates uptake blood to liver (hepatocytes)
hepatoprotectant
hepatotherapeutic
hepatotoxicity
anti-hepatoxic
hlda inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlde inhibitor (glycero-manno-heptose-7-phosphate kinase)
her-2 inhibitor (human epidermal growth)
herbicide
herbicide (post-emergence)
herbicide (pre-emergence)
herg channel blocker (increase qt interval, cardiac risk)
herg channel optimized (qt interval decreased)
anti-viral (cmv, herpes-2 cytomegalo)
anti-viral (herpes genitalis)
hsv-1 imaging (herpes simplex)
anti-viral (hsv-1 herpes simplex)
dermatitis suppressant (herpetiformis or atopic)
20-hete synthase inhibitor (hydroxyeicosatetraenoic acid)
c-myc-max heterodimer disruptor
human enterovirus inhibitor (hev-71/echo)
hgf inhibitor (hepatocyte growth factor)
map4k4 inhibitor (mitogen-activated kinase, hgk)
hedgehog signaling antagonist (hh, smo)
anti-perspirant (anti-hidrotic)
hif-1 inhibitor (hypoxia inducible factor)
hdl-c high density lipoprotein elevator
eps high (extrapyramidal effect)
p-gp efflux high (p-glycoprotein)
high volume industrial chem. epa (450,000 kg/yr)
cytochrome p680 photosynthesis inhibitor (hill reaction)
treatment facial hirsutism
h1 histamine agonist
h3 histamine agonist
h4 histamine agonist
h2 histamine agonist
h2 histamine antagonist
h4 histamine antagonist
h1 histamine antagonist
h3 histamine antagonist/inverse agonist
h3 histamine binder
h1 histamine binder
h4 histamine ligand
histamine n-methyl-transferase inhibitor
anti-histamine (non-sedating)
anti-histaminic
histidine decarboxylase inhibitor
prrb-prra two-component histidine kinase
cd4-mhc binding inhibitor (major histocompatability complex)
anti-amebic (entamoeba histolytica)
anti-protozoal (histomonas)
kat3 inhibitor (histone acetyltransferase)
histone acetyltransferase inhibitor (hat)
histone deacetylase-1 inhibitor (hdac-1)
histone deacetylase-10 inhibitor (hdac-10)
histone deacetylase-11 inhibitor (hdac-11)
histone deacetylase-2 inhibitor (hdac-2)
histone deacetylase-3 inhibitor (hdac-3)
histone deacetylase-4 inhibitor (hdac-4)
histone deacetylase-5 inhibitor (hdac-5)
histone deacetylase-6 inhibitor (hdac-6)
histone deacetylase-7 inhibitor (hdac-7)
histone deacetylase-8 inhibitor (hdac-8)
histone deacetylase-9 inhibitor (hdac-9)
jmjd2 inhibitor (jumonji domain histone demethylase)
kdm2/7 inhibitor (histone lysine demethylase)
hmt-dot1l inhibitor (histone methyl transferase)
anti-viral (hiv)
hiv-1 chemokine antagonist
hiv-1 maturation inhibitor
hiv-1ca inhibitor (capsid assembly)
anti-viral (hiv, attachment/ entry inhibitor)
hiv-gp41 inhibitor (glycoprotein)
dormant hiv inhibitor
hiv integrase inhibitor
anti-neoplastic (hiv lymphoid)
hiv-nucleocapsid binder (nc)
hiv protease dimerization inhibitor
hiv protease inhibitor
sl3-rna hiv replication inhibitor
anti-viral (hiv, reverse transcriptase)
anti-viral (hiv, tat)
anti-neoplastic (hl-60 leukemia)
hlda inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlde inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlig-i inhibitor (human dna ligase-i)
hmg-coa reductase inhibitor (hmgr, ec 1.1.1.34)
hmg-coa reductase inhibitor (hmgr, ec 1.1.1.34)
hmt-dot1l inhibitor (histone methyl transferase)
anti-neoplastic (non-hodgkin lymphoma)
anti-protozoal (cryptosporidium parvum/ hominis)
ezh-2 inhibitor (enhancer zeste homolog)
mechanistic hop
thyroid hormone
pineal hormone
lh agonist (luteinizing hormone)
pth-1 antagonist (parathyroid hormone)
fsh agonist (follicle stimulating hormone)
fsh antagonist (follicle stimulating hormone)
acth inhibitor (adrenocorticotropic hormone)
lhrh/gnrh antagonist (luteinizing/gonadotropin-releasing hormone)
thyrotropin-releasing hormone agonist (trh)
corticotropin-releasing hormone antagonist
anti-neoplastic (breast, hormone-dependent)
treatment of sex-hormone disorders
juvenile hormone esterase inhibitor
melanin concentrating hormone inhibitor (mch-1)
growth hormone inhibitor (secretagogue)
rorgt antagonist (nuclear hormone receptor gamma)
estrogenic hrt (hormone replacement therapy)
hormone sensitive lipase inhibitor (hsl)
growth hormone stimulant
insecticide (housefly)
4-hppd inhibitor (hydroxyphenyl pyruvate dioxygenase)
hppk inhibitor (6-hydroxymethyl-7,8-dihydropetrin kinase)
anti-hpv (human papilloma virus)
eif4e inhibitor (eukaryotic initiation factor, hri)
estrogenic hrt (hormone replacement therapy)
dhodh-hs inhibitor (dihydroorate dehydrogenase-human)
hsc transplant enhancer (human stem cell)
11b-hsd-1 inhibitor (11b-hydroxysteroid dehydrogenase-1)
17b-hsd1 inhibitor (17b-hydroxysteroid dehydrogenase-1, ec 1.1.1.62)
17b-hsd2 inhibitor (17b-hydroxysteroid dehydrogenase-2)
hormone sensitive lipase inhibitor (hsl)
hsp-27 inhibitor (heat shock protein)
hsp-70 inhibitor (heat shock protein)
hsp-78d inhibitor (grp-78 glucose regulated protein)
hsp-90 c-terminal inhibitor
hsp-90 inhibitor (heat shock protein)
anti-viral (hsv-1 herpes simplex)
anti-viral (hsv-1 & hsv-2)
hsv-1 imaging (herpes simplex)
anti-viral (hsv-1 & hsv-2)
5-ht serotonin antagonist
5-ht serotonin reuptake inhibitor (ssri)
5-ht serotonin transport inhibitor (sert)
5-ht serotonin uptake inhibitor
5-ht1-a,b,d autoreceptor antagonist
5-ht1a serotonin agonist
5-ht1a serotonin antagonist
5-ht1a serotonin binder
5-ht1b serotonin agonist
5-ht1b serotonin antagonist
5-ht1b serotonin inverse agonist
5-ht1bd serotonin agonist
5-ht1d serotonin agonist
5-ht1d serotonin antagonist
5-ht1f serotonin agonist
5-ht2 serotonin agonist
5-ht2 serotonin antagonist
5-ht2a serotonin agonist
5-ht2a serotonin antagonist
5-ht2b serotonin agonist
5-ht2b serotonin antagonist
5-ht2c serotonin agonist
5-ht2c serotonin antagonist
5-ht3 serotonin agonist
5-ht3 serotonin antagonist
5-ht3 serotonin ligand
5-ht4 serotonin agonist
5-ht4 serotonin antagonist
5-ht5a serotonin antagonist
5-ht6 serotonin agonist
5-ht6 serotonin antagonist
5-ht7 serotonin agonist
5-ht7 serotonin antagonist
5-htp serotonin uptake inhibitor
cox-1 inhibitor (cyclooxygenase, human)
dhodh-hs inhibitor (dihydroorate dehydrogenase-human)
human carcinogen (iarc)
human chymase inhibitor
hlig-i inhibitor (human dna ligase-i)
human enterovirus inhibitor (hev-71/echo)
her-2 inhibitor (human epidermal growth)
human immunoproteasome inhibitor (b1i selective)
human leukocyte elastase inhibitor
human neutrophil elastase inhibitor
human pancreatic elastase inhibitor
human pancreatic trypsin inhibitor
anti-hpv (human papilloma virus)
chimp-human pharmacokinetics compared
anti-viral (human rhinovirus)
hsc transplant enhancer (human stem cell)
telomerase inhibitor human (trap assay)
huratat-1 inhibitor (human uric acid transporter)
huntington disease treatment
poly-q anti-aggregant (anti-huntington's)
huratat-1 inhibitor (human uric acid transporter)
huvec cell inhibition
hyaluronidase inhibitor
aryl hydrocarbon hydrolase inducer
aryl hydrocarbon hydroxylase inhibitor (ahh)
ahr antagonist (aryl hydrocarbon receptor)
ahr agonist (aryl hydrocarbon receptor)
sahr modulator (selective aromatic hydrocarbon receptor)
hydrocholeretic (bile dilution)
sodium-hydrogen exchange inhibitor (nhe-1)
hydrogen peroxide probe
h2s donor (hydrogen sulfide releasing)
faah inhibitor (fatty acid amide hydrolase)
aryl hydrocarbon hydrolase inducer
leukotriene a4 hydrolase inhibitor
epoxide hydrolase inhibitor
fab-z inhibitor (b-hydroxacyl-acp-dehydrase)
20-hete synthase inhibitor (hydroxyeicosatetraenoic acid)
tph-1 inhibitor (tryptophan hydroxylase)
phd2 inhibitor (prolyl hydroxylase-2)
dopamine b-hydroxylase inhibitor
tyrosine hydroxylase inhibitor
aryl hydrocarbon hydroxylase inhibitor (ahh)
deoxyhypusine hydroxylase inhibitor (ec 1.14.99.29)
kynurenine hydroxylase inhibitor (ec 3.7.1.3)
hppk inhibitor (6-hydroxymethyl-7,8-dihydropetrin kinase)
shmt inhibitor (serine hydroxymethyltransferase
4-hppd inhibitor (hydroxyphenyl pyruvate dioxygenase)
15-pgdh inhibitor (15-hydroxyprostaglandin dehydrogenase)
11b-hsd-1 inhibitor (11b-hydroxysteroid dehydrogenase-1)
17b-hsd1 inhibitor (17b-hydroxysteroid dehydrogenase-1, ec 1.1.1.62)
17b-hsd2 inhibitor (17b-hydroxysteroid dehydrogenase-2)
larvicide (hylemya platura, seed corn borer)
anti-adhd (attention deficit hyperactivity disorder)
apo-induced hyperactivity inhibitor
anti-hypercholesterolemic
hyperglycemic (pro-diabetic)
anti-hyperlipidemic (hypolipidemic dyslipidemic)
anti-hyperlipoproteinemic
anti-hyperpigmentation
bph treatment (benign prostatic hyperplasia)
hcn-1 blocker (hyperpolarization-activated cyclic nucleoside-gated)
hcn-2 blocker (hyperpolarization-activated cyclic nucleoside-gated)
keratolytic (suppreses keratinocyte hyperproliferation)
anti-hypertensive
hypertensive (pulmonary)
anti-hypertensive (pulmonary, pah)
anti-hyperthyroid
anti-prostatic hypertrophy
cardiac hypertrophy treatment
hypnotic
hypoammoniuric (anti-ammoniuric)
hypocalciuric
hypocholesterolemic
hypoglycemic
hypoglycemic (oral)
anti-hyperlipidemic (hypolipidemic dyslipidemic)
hyponatremia treatment (low sodium)
pituitary inhibitor (hypophysis)
ophthalmic hypotensive
vasoconstrictor (vasopressor, anti-hypotensive)
anti-pyretic hypothermic (anti-febric)
cytotoxic (hypoxia-activated)
hypoxia activated prodrug
hypoxia imaging
hif-1 inhibitor (hypoxia inducible factor)
anti-hypoxic (anti-anoxic)
imidazoline-2 ligand (i2)
prostaglandin i2 agonist
prostaglandin i2 antagonist
bir2 selective (second baculovirus iap repeat)
human carcinogen (iarc)
ibat inhibitor (ileal bile acid transporter)
ibd treatment (irritable bowel disease) crohn's
icmt inhibitor (isoprenylcysteine carboxyl transferase)
ics (inhaled corticosteroid)
ide inhibitor (insulin-degrading enzyme)
ipf treatment (ideopathic pulmonary fibrosis)
idh-1 inhibitor (isocitrate dehydrogenase)
ido inhibitor (indolamine-2,3-deoxygenase, ec 1.13.11.52)
idp inhibitor (inhibitor differentiation protein)
igf-1 inhibitor (insulin-like growth factor)
iglu-a2 modulator (ionotropic glutamate)
iglur-5 binder (ionotropic glutamate-5)
glutamate carboxypeptidase ii inhibitor (gcp-ii)
angiotensin ii agonist
urotensin ii antagonist
angiotensin ii antagonist
angiotensin ii binder
arginase ii inhibitor
mitochondrial electron transport complex ii inhibitor
topoisomerase ii inhibitor
succinate dehydrogenase (complex ii) inhibitor (ec 1.3.5.1)
dehydroquinase ii inhibitor (ec 4.2.1.10)
fas-ii inhibitor (fatty acid synthase)
glutamate carboxypeptidase ii inhibitor (gcp-ii)
plasmepsin ii inhibitor (malarial)
gp iib/iiia inhibitor (gycoprotein)
mitochondrial electron transport complex iii (qi) inhibitor
aph3'-iiia inhibitor (aminoglycoside modifying enzyme)
gp iib/iiia inhibitor (gycoprotein)
ik/sk potassium channel modulators
ikca calcium activated potassium channel blocker
ikkb-1 inhibitor (i-kappa-kinase-beta)
ikkb-2 inhibitor (i-kappa kinase beta)
ikke inhibitor (i-kappa-kinase epsilon)
ikur inhibitor (potassium ion current, atrium)
interleukin-13 blocker (il-13)
interleukin-1b converting enzyme inhibitor (il-1b)
interleukin-2 blocker (il-2)
interleukin-5 blocker (il-5)
interleukin-6 blocker (il-6)
ibat inhibitor (ileal bile acid transporter)
mglur1 imager (metabotropic glutamate)
myocardial imaging
beta-amyloid imaging
spin label imaging
melanoma imaging
hypoxia imaging
brain imaging
hsv-1 imaging (herpes simplex)
pet imaging (positron emission tomography)
cardiac pet imaging (positron emission tomography)
spect imaging (single photon emission computed tomography)
imidazoline-2 ligand (i2)
ir-1 ligand (imidazoline receptor-1)
imitation grape flavoring
ccr5 antagonist (chemokine-5, immune cell receptor)
immunomodulator (autoimmune therapy)
human immunoproteasome inhibitor (b1i selective)
immunostimulant
immunosuppressant (prevents implant rejection)
inosine-5'-monophosphate dehydrogenase inhibitor (impdh)
immunosuppressant (prevents implant rejection)
atp-ase inhibitor (incl. vacuolar, v-atp-ase)
urinary incontinence (dysuria, overactive bladder, oab)
ethr inhibitor (incr. ethionamide action)
circadian period increase
positive chronotropic (increase heart rate)
herg channel blocker (increase qt interval, cardiac risk)
increased bone formation (anabolic)
ido inhibitor (indolamine-2,3-deoxygenase, ec 1.13.11.52)
ebi-2 antagonist (epstein-barr virus-induced)
soicr suppressor (store-overloaded-induced calcium release)
apo-induced hyperactivity inhibitor
anti-neoplastic (chemo-induced tumors)
hif-1 inhibitor (hypoxia inducible factor)
inducible nitric oxide synthase inhibitor (inos)
itk inhibitor (interleukin-2 inducible t-cell kinase)
seizure inducing
high volume industrial chem. epa (450,000 kg/yr)
treatment for myocardial infarction or perfusion injury
mock-infected mt4 cell toxicity
anti-septic (anti-infective)
anti-inflammatory
gastroprotective (gastric anti-inflammatory)
anti-inflammatory (cytokine suppressing, csaid)
anti-inflammatory non-steroidal (nsaid)
anti-inflammatory (ophthalmic-topical)
anti-inflammatory (respiratory)
anti-inflammatory (topical)
anti-inflammatory (veterinary)
anti-viral (influenza)
anti-bacterial (haemophilus influenzae gram-)
perfume or fragrance ingredient/intermediate
analgesic (inhalation)
anesthetic (inhalation)
ics (inhaled corticosteroid)
somatostatin antagonist (srif release-inhibiting factor)
tnks-1 inhibitior (tankyrase-1)
meallo-beta-lactamase inhibitors
dub inhibitors (deubiquitinating enzymes, pan)
mif (macrophage migration inhibitory factor)
inhibits excretion of penicillin
eif4e inhibitor (eukaryotic initiation factor, hri)
translation initiation inhibitor
anti-cns injury
treatment for myocardial infarction or perfusion injury
anti-cerebral disease/injury/palsy
inducible nitric oxide synthase inhibitor (inos)
inosine-5'-monophosphate dehydrogenase inhibitor (impdh)
inositol monophosphatase inhibitor
ire-1 inhibitor (inositol-requiring enzyme)
ip3 inositol triphosphate agonist
positive inotrope (strengthen muscle contraction)
negative inotrope (weakens muscle contraction)
insect growth regulator
insect neurotoxin
insect pheromone
insect repellant
insecticide
insecticide (aphid)
insecticide (bedbugs)
insecticide (cockroach)
insecticide (fleas)
insecticide (housefly)
insecticide (mosquito adult)
insecticide (mosquito larvae)
insecticide (potential)
insecticide (red mites)
insecticide (spodoptura eridania, southern army worm)
insecticide synergist
insecticide (systemic)
insecticide (thrip)
insecticide (turf)
insecticide (veterinary)
sleep promoter (anti-insomnia)
anti-cerebral insufficiency
ide inhibitor (insulin-degrading enzyme)
igf-1 inhibitor (insulin-like growth factor)
insulin mimic (modulator)
irtk activator (insulin receptor tyrosine kinase)
irap inhibitor (insulin-regulated aminopeptidase)
pancreatic insulin secretion inhibitor
insulin sensitizer
insulinotropic
ledgf-p75 integrase blocker (lens epithelial-cell derived)
hiv integrase inhibitor
vla4 antagonist (very late antigen, eosinophil integrin)
integrin antagonist
integrin antagonist (a4b1~a4b7)
integrin antagonist (a5b1)
integrin antagonist (a5b3)
integrin antagonist (aiibb3)
integrin antagonist (avb3)
integrin antagonist (avb5)
integrin antagonist (avb6)
mml1-menin interaction blocker
fraxin/ubiquitin interaction inhibition
thyroid coactivator interaction inhibitor
eif4e/eif4g protein interaction inhibitor
cytochrome p450 inhibitor (drug interaction?)
cytochrome p450 inducer (drug interaction?)
dna binder (non-intercalating)
dna intercaltor
interferon inducer
interleukin-13 blocker (il-13)
interleukin-1b converting enzyme inhibitor (il-1b)
interleukin-2 blocker (il-2)
itk inhibitor (interleukin-2 inducible t-cell kinase)
interleukin-5 blocker (il-5)
interleukin-6 blocker (il-6)
interleukin-8 blocker
irak-4 inhibitor (interleukin receptor associated kinase)
perfume or fragrance ingredient/intermediate
hcv ires inhibitor (internal ribosome entry site, hepatitis c)
dna interstrand cross linker
anti-bacterial (intestinal)
anti-septic (intestinal)
amebicide (intestinal)
anti-upper intestinal disorders
anti-neoplastic (gastro-intestinal, gist)
gastroprokinetic (gastro-intestinal stimulant)
intracellular superoxide generator
anesthetic (intravenous)
ph indicator, non-invasive
kir potassium channel modulator (inwardly rectifying)
iodine source
asic blocker (acid sensitive ion channel)
ion channel blocker
ikur inhibitor (potassium ion current, atrium)
selective ionophore
iglu-a2 modulator (ionotropic glutamate)
iglur-5 binder (ionotropic glutamate-5)
ip3 inositol triphosphate agonist
ipf treatment (ideopathic pulmonary fibrosis)
ir-1 ligand (imidazoline receptor-1)
irak-4 inhibitor (interleukin receptor associated kinase)
irap inhibitor (insulin-regulated aminopeptidase)
ire-1 inhibitor (inositol-requiring enzyme)
hcv ires inhibitor (internal ribosome entry site, hepatitis c)
iron chelator (siderophore)
endosomal/lysosomal labile iron probe
covalent protein modifier (irreversible)
ibd treatment (irritable bowel disease) crohn's
counter-irritant
terpine (often toxic/irritant)
counter-irritant (topical)
irtk activator (insulin receptor tyrosine kinase)
ischemic stroke treatment (cardiac/cerebral)
ishemia/reperfusion treatment
idh-1 inhibitor (isocitrate dehydrogenase)
ksi inhibitor (ketosteroid isomerase)
sterol d8d7 isomerase binder
peptidyl prolyl isomerase inhibitor (fkbp)
retinoid isomerohydrolase inhibitor
icmt inhibitor (isoprenylcysteine carboxyl transferase)
dxr inhibitor (deoxyxylulose-phosphate reductoisomerase, ispc)
carcinogen cal.prop.65 or isscan
anti-fungal (trichophyton spp., ringworm, jock-itch)
itk inhibitor (interleukin-2 inducible t-cell kinase)
topoisomerase iv inhibitor
mitochondrial electron transport complex iv inhibitor
factor ix-a inhibitor
jak-1 inhibitor (janus kinase-1)
jak-2 inhibitor (janus kinase-2)
jak-3 inhibitor (janus kinase 3)
jak-1 inhibitor (janus kinase-1)
jak-2 inhibitor (janus kinase-2)
jak-3 inhibitor (janus kinase 3)
jcl inhibitor (jurkat cell lysis)
jmjd2 inhibitor (jumonji domain histone demethylase)
jnk-3 inhibitor (c-jun-n-terminal kinase)
jnk inhibitor (c-jun n-terminal kinase)
anti-fungal (trichophyton spp., ringworm, jock-itch)
jmjd2 inhibitor (jumonji domain histone demethylase)
jnk inhibitor (c-jun n-terminal kinase)
jnk-3 inhibitor (c-jun-n-terminal kinase)
gap junction modifier
jcl inhibitor (jurkat cell lysis)
anti-neoplastic (jurkat leukemia)
juvenile hormone esterase inhibitor
k-secretase inhibitor
k2-b opioid agonist
k2p potassium channel modulator (twin pore)
gluk-1 agonist (glutamate kainate)
gluk-1 antagonist (glutamate kainate)
glur-2 partial agonist (glutamate kainate)
kainate agonist
kainate antagonist
glur5 kainate antagonist
plasma kallikrein inhibitor
anti-bacterial (mycobacterium kansasii gram+)
nuclear factor kappa b inhibitor (nf-k-b)
ikkb-1 inhibitor (i-kappa-kinase-beta)
ikkb-2 inhibitor (i-kappa kinase beta)
ikke inhibitor (i-kappa-kinase epsilon)
kappa opioid agonist (sedating)
kappa opioid antagonist
analgesic (kappa selective)
kat-2 inhibitor (kynurenine aminotransferase, ec 2.6.1.7)
kat3 inhibitor (histone acetyltransferase)
kca1.1 potassium channel opener (ca and voltage gated)
potassium channel k-7 modulator/inhibitor (kcnq-2)
kdm2/7 inhibitor (histone lysine demethylase)
vegf-2 inhibitor (vascular endothelial g.f., kdr, fr)
nrf2 activator (keap-1 modifier)
keratolytic (suppreses keratinocyte hyperproliferation)
anti-psoriatic (keratolytic)
anti-pruritic (keratolytic)
keratolytic (suppreses keratinocyte hyperproliferation)
anti-actinic keratosis
akr1c3 inhibitor (aldo-keto reductase)
fab-b/f inhibitor (b-ketoacetyl-acp synthase 1/2)
fab-h inhibitor (b-ketoacetyl acp synthase-3)
dk treatment (diabetic ketoacidosis)
fab-g inhibitor (b-ketoacyl-acp-reductase)
ketohexokinase inhibitor
ksi inhibitor (ketosteroid isomerase)
high volume industrial chem. epa (450,000 kg/yr)
anti-neoplastic (renal / kidney)
chronic kidney disease treatment
polycystic kidney disease treatment
kidney failure protectant
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
cxcr-3 chemokine (killer) antagonist
prrb-prra two-component histidine kinase
lck sh2 inhibitor (lymphocyte-specific protein tyrosine kinase)
erk-1/erk-2 inhibitor (extracellular signal-regulated kinase)
dna-pk inhibitor (dna-dependent protein kinase)
alk inhibition (anaplastic lymphoma kinase)
flt-3 inhibitor (tyrosine kinase)
tyk-2 inhibitor (tyrosine kinase)
jnk inhibitor (c-jun n-terminal kinase)
tmpk inhibitor (thymidine monophosphate kinase)
syk inhibitor (spleen tyrosine kinase)
pk inhibitor (pyruvate kinase)
pk activator (pyruvate kinase)
ck1-inhibitor (casein kinase)
irtk activator (insulin receptor tyrosine kinase)
ampk activator (adenosine monophosphate activated kinase)
sphk-1 inhibitor (sphingosine kinase)
vzv-tk inhibitor (varicella-zoster thymidine kinase)
c-kit inhibitor (cd 117, tyrosine kinase)
cdk-5 inhibitor (cyclin-dependent kinase)
plk-1 inhibitor (polo-like kinase)
fak inhibitor (focal adhesion kinase)
mnk-1 inhibitor (mitogen-activated kinase)
itk inhibitor (interleukin-2 inducible t-cell kinase)
ask-1 inhibitor (apoptosis-regulating kinase)
dyrk-1a inhibitor (dual-specificity tyrosine kinase)
sgk-1 inhibitor (serum glucocorticoid-regulated kinase)
irak-4 inhibitor (interleukin receptor associated kinase)
clk inhibitor (cd2-like kinase)
cdpk-1 inhibitor (calcium-dependent protein kinase)
ack1 inhibitor (activated cdc42 associated kinase)
pak-4 inhibitor (p21-activated kinase)
trk-a inhibitor (tropomyosin-related kinase)
lrrk2 inhibitor (leucine-rich repeat kinase)
1heh inhibitor (nicotinamide ribose kinase)
pyk2 inhibitor (proline-rich tyrosine kinase)
perk inhibitor (endoplasmic reticulum kinase)
trk-b inhibitor (tropomyocin-related kinase)
hlda inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlde inhibitor (glycero-manno-heptose-7-phosphate kinase)
ck-1a enhancer (casein kinase)
pkk-4 inhibitor (polo-like kinase)
mer-rtk inhibitor (receptor tyrosine kinase)
ark-5 inhibitor (ampk-related kinase)
pi4kiiia inhibitor (phosphatidylinositol kinase)
ck-1d inhibitor (casein kinase)
trk-b agonist (tyrosine kinase)
apkc modulator (atypical protein kinase)
sphk-2 inhibitor (sphingosine kinase)
dck inhibitor (deoxycytidine kinase)
hppk inhibitor (6-hydroxymethyl-7,8-dihydropetrin kinase)
jnk-3 inhibitor (c-jun-n-terminal kinase)
map4k2 inhibitor (mitogen-activated protein kinase)
ck2 inhibitor (casein kinase)
dlk,map3k12 inhibitor (dual leucine zippper kinase)
pank-3 inhibitor (pantothenate kinase)
pank-3 activator (pantothenate kinase)
pank-1b inhibitor (pantothenate kinase)
limk-1 inhibitor (lim kinase)
gak inhibitor (cyclin-g associated kinase)
pfbkfb3 inhibitor (metabolic kinase)
rock-1 inhibitor (rho kinase-1)
chk-1 inhibitor (checkpoint kinase-1)
mlk-1 inhibitor (mixed-lineage kinase-1)
jak-1 inhibitor (janus kinase-1)
cyclin-dependent kinase-1 inhibitor (cdk1)
mlk-2 inhibitor (mixed-lineage kinase-2)
rock-2 inhibitor (rho kinase-2)
jak-2 inhibitor (janus kinase-2)
chk-2 inhibitor (checkpoint kinase-2)
cyclin-dependent kinase-2 inhibitor (cdk2)
jak-3 inhibitor (janus kinase 3)
mlk-3 inhibitor (mixed-lineage kinase-3)
glycogen synthase kinase-3-beta inhibitor (gsk-3beta)
cyclin-dependent kinase-4 inhibitor (cdk4)
cdk5 inhibitor (cyclin-dependent kinase-5)
cenp-e inhibitor (centromere-assoc. protein-e)(kinase-7)
cyclin-dependent kinase-7 inhibitor (cdk-7)
cyclin-dependent kinase-9 inhibitor (cdk9)
tyrosine kinase-a inhibitor
glycogen synthase kinase-a inhibitor (gsk-3a)
protein kinase a inhibitor (pka)
pi-3ka inhibitor (phosphoinositide kinase alpha)
mnk/ar degrader (mitogen-activated kinase & androgen receptor)
protein kinase b inhibitor (akt)
protein kinase b inhibitor (akt-1)
protein kinase b inhibitor (akt-2)
protein kinase b inhibitor (akt-3)
ikkb-1 inhibitor (i-kappa-kinase-beta)
ikkb-2 inhibitor (i-kappa kinase beta)
pi-3kb inhibitor (phosphoinositide kinase beta)
btk inhibitor (bruton's tyrosine kinase, beta cells)
pkc-theta inhibitor (protein kinase-c)
protein kinase c activator
pkc-e inhibitor (protein kinase-c-epsilon)
protein kinase c inhibitor
pkcz inhibitor (protein kinase-c zeta)
protein kinase-c1 modulator
protein kinase ck2 inhibitor
protein kinase d inhibitor
pi-3kd inhibitor (phosphoinositide kinase delta)
tmk inhibitor (thymidylate kinase, ec 2.7.4.9)
ikke inhibitor (i-kappa-kinase epsilon)
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
protein kinase g inhibitor
pi-3kg inhibitor (phosphoinositide kinase gamma)
map4k4 inhibitor (mitogen-activated kinase, hgk)
c-src kinase inhibitor
erb-tyrosine kinase inhibitor
c-src tyrosine kinase inhibitor
aurora-b kinase inhibitor
cmet tyrosine kinase inhibitor
cdc7 kinase inhibitor
aurora-a kinase inhibitor
cfms kinase inhibitor
c-raf kinase inhibitor
pim-2 kinase inhibitor
ul-97 kinase inhibitor
bcr-abl and t315i-mutant kinase inhibitor
aurora-c kinase inhibitor
ret kinase inhibitor
pim-3 kinase inhibitor
abl protein kinase inhibitor (bcr-abl)
b-raf kinase inhibitor (braf)
diacylglycerol kinase inhibitor (ec 2.7.1.107)
adenosine kinase inhibitor (ec 2.7.1.20)
thymidine kinase inhibitor (ec 2.7.1.21)
pgk phosphoglycerate kinase inhibitor (ec 2.7.2.3)
eef2-kinase inhibitor (eukaryotic elongation factor)
lymphocyte-specific kinase inhibitor (lck)
mst-1 kinase inhibitor (mammalian sterile-20)
mitogen stress response kinase inhibitor(msk-1)
mitogen-activated protein kinase inhibitor (p38-map)
pyruvate dehydrogenase kinase inhibitor (pdhk)
pim-1 kinase inhibitor (proto-oncogene)
protein tyrosine kinase inhibitor (ptk)
protein kinase inhibitor (rsk2)
mitochondrial thymidine kinase inhibitor (tk-2)
erk-5 inhibitor (extracellular signal-regulated kinase, mapk-7)
dyrk-1b (dual-specificity tyrosine kinase, mirk)
mkp-1 inhibitor (mitogen activated protein kinase phosphatase)
pi-3kc inhibitor (phosphoinositide kinase) (vps-34)
prolificate for agc kinases
eg5 inhibitor (mitotic kinesin)
kinesin spindle protein inhibitor (ksp)
kir potassium channel modulator (inwardly rectifying)
c-kit inhibitor (cd 117, tyrosine kinase)
anti-bacterial (klebsiella pneumoniae gram-)
kmo inhibitor (kynurenine-3- monooxygenase)(ec1.14.13.9)
kmo inhibitor (kynurenine-3 oxygenase)
knockdown agent
anti-fungal (candida krusei)
ksi inhibitor (ketosteroid isomerase)
kinesin spindle protein inhibitor (ksp)
kv 1.3 inhibitor
kmo inhibitor (kynurenine-3- monooxygenase)(ec1.14.13.9)
kmo inhibitor (kynurenine-3 oxygenase)
kat-2 inhibitor (kynurenine aminotransferase, ec 2.6.1.7)
kynurenine hydroxylase inhibitor (ec 3.7.1.3)
l-type calcium channel blocker
uch-l1 inhibitor (ubiquitin-specific protease)
anti-dyskinetic (giles de la tourette's syndrome)
endosomal/lysosomal labile iron probe
oxytocin antagonist (tocolytic, delays labor)
anti-neutropenia (lack of neutrophils)
lacrimator
beta-lactamase ctxm-a inhibitor
beta lactamase inhibitor (ec 3.5.2.6)
meallo-beta-lactamase inhibitors
beta-lactamase resistant
pfldh inhibitor (p.falciparum lactate dehydrogenase)
ldh-a inhibitor (lactate dehydrogenase)
lamprey pheromone
lampricide
lanosterol-14-a-demethylase inhibitor
mmpl-3 inhibitor (mycobacterial membrane large)
insecticide (mosquito larvae)
larvicide
larvicide (colorado potato beetle)
larvicide (hylemya platura, seed corn borer)
larvicide (rice borer)
vla4 antagonist (very late antigen, eosinophil integrin)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
laxative (cathartic, prokinetic)
elovl-6 inhibitor (fatty acid elongase-6, lce, face)
lymphocyte-specific kinase inhibitor (lck)
lck sh2 inhibitor (lymphocyte-specific protein tyrosine kinase)
ldh-a inhibitor (lactate dehydrogenase)
ldlr agonist (low-density lipoprotein)
ledgf-p75 integrase blocker (lens epithelial-cell derived)
restless leg treatment
anti-protozoal (leishmaniasis)
slos treatment (smith-lemli-opitz syndrome)
lennox-gastaut syndrome treatment
ledgf-p75 integrase blocker (lens epithelial-cell derived)
leprosy treatment (hansen's disease)
lesch-nyhan treatment
anti-bacterial (anthrax lethal factor inhibitor)
aminopeptidase inhibitor (alanyl and/or leucine)
lrrk2 inhibitor (leucine-rich repeat kinase)
dlk,map3k12 inhibitor (dual leucine zippper kinase)
leucyl t-rna synthesis inhibitor
anti-neoplastic (p388 leukemia)
anti-neoplastic (hl-60 leukemia)
anti-neoplastic (acute monocytic leukemia)
anti-neoplastic (jurkat leukemia)
anti-neoplastic (cll chronic lymphocytic leukemia)
apl treatment (acute promyelocytic leukemia)
mcl-1 inhibitor (myeloid cell leukemia)
anti-neoplastic (acute lymphoblastic leukemia, all)
anti-neoplastic (acute myelogenous leukemia, aml)
chronic myeloid leukemia (cml) treatment
anti-neoplastic (leukemia l-1210)
mll inhibition (mixed lineage leukemias)
anti-leukemic
carcinogen (leukemic)
anti-leukemic (lymphoblasts)
human leukocyte elastase inhibitor
lymphocyte/leukocyte function assoc. antigen antagonist (lfa-1)
leukopoietic stimulant
leukotriene a4 hydrolase inhibitor
cysteinyl leukotriene antagonist
leukotriene antagonist
ltd4-lte4 leukotriene antagonist
ltd-4 leukotriene antagonist
cysteinyl leukotriene antagonist (cys-lt1)
leukotriene b4 agonist
leukotriene b4 antagonist
leukotriene b4 synthesis inhibitor (ltb4)
leukotriene c4 antagonist
leukotriene d4 antagonist
leukotriene inhibitor
lymphocyte/leukocyte function assoc. antigen antagonist (lfa-1)
lh agonist (luteinizing hormone)
lhrh/gnrh antagonist (luteinizing/gonadotropin-releasing hormone)
pediculicide (lice)
half-life in animal/plasma
radiodiagnostic/ligand
sigma 2 ligand
sigma-1 ligand
5-ht3 serotonin ligand
h4 histamine ligand
fkbp51 ligand
hemozoin ligand
brd ligand (bromodomain acetyl-lysine)
cxcr7 ligand (chemokine)
nmda ligand (glu-n1/2b selective)
imidazoline-2 ligand (i2)
ir-1 ligand (imidazoline receptor-1)
npff ligand (neuropeptide ff)
rar-b2 ligand (retinoic acid receptor b2)
vacht ligand (vesicular acetylcholine transporter)
ddl inhibitor (d-alanine-d-alanine ligase)
hlig-i inhibitor (human dna ligase-i)
mur-d ligase inhibitor (glutamic acid)
non-mutagenic (likely)
limk-1 inhibitor (lim kinase)
limk-1 inhibitor (lim kinase)
mlk-1 inhibitor (mixed-lineage kinase-1)
mlk-2 inhibitor (mixed-lineage kinase-2)
mlk-3 inhibitor (mixed-lineage kinase-3)
mll inhibition (mixed lineage leukemias)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
xiap antagonist (x-linked inhibitor apoptosis protein)
dna interstrand cross linker
magl inhibitor (monoacylglycerol lipase)
dagl-a inhibitor (diacylglycerol lipase-a)
endothelial lipase inhibitor
microbial lipase inhibitor
pancreatic lipase inhibitor
hormone sensitive lipase inhibitor (hsl)
monoacylglycerol lipase inhibitor (mgl)
anti-oxidant (lipid)
lipid peroxidation inhibitor
acc1 inhibitor (acetyl-coa-carboxylase-1, lipid synthesis)
lipid synthesis inhibitor
annexin binder (lipocortin)
ldlr agonist (low-density lipoprotein)
lipoprotein assembly inhibitor
hdl-c high density lipoprotein elevator
liposome potentiator
12-lipoxygenase inhibitor
15-lipoxygenase inhibitor
5-lipoxygenase inhibitor (flap, ec 1.13.11.12)
toxin, liver
anti-neoplastic (hepatic, liver)
carcinogen (mouse liver)
anti-hepatic disorders (liver)
dihydrofolate reductase inhibitor (dhrf, chicken liver)
dihydrofolate reductase inhibitor (dhfr, rat liver)
nafld treatment (non-alcoholic fatty liver disease)
mediates uptake blood to liver (hepatocytes)
anti-malarial (liver stage)
lxr-a agonist (liver-x receptor)
lxr-b agonist (liver-x receptor-b)
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
anesthetic (local)
anti-asthmatic (local)
mineralocorticoid (na retention, k loss)
bone loss inhibitor (dental)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
ce inhibitor (carboxyl esterase, low ache & bche)
ldlr agonist (low-density lipoprotein)
eps relatively low (extrapyramidal effect)
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
hyponatremia treatment (low sodium)
low toxicity to mice or fibroblast cells
lpa-1 antagonist (lysophosphatidic acid)
lpx-c inhibitor (zinc-dependent acetylase)
lrrk2 inhibitor
lrrk2 inhibitor (leucine-rich repeat kinase)
lsd-1 inhibitor (lysine specific demethylase)
lsd treatment (lysosomal storage disease)
cysteinyl leukotriene antagonist (cys-lt1)
leukotriene b4 synthesis inhibitor (ltb4)
ltd-4 leukotriene antagonist
ltd4-lte4 leukotriene antagonist
ltd4-lte4 leukotriene antagonist
luciferase inhibitor
anti-neoplastic (lung non-small cell, nsclc)
anti-neoplastic (lung small cell)
sle treatment (systemic lupus erythematous)
lhrh/gnrh antagonist (luteinizing/gonadotropin-releasing hormone)
lh agonist (luteinizing hormone)
luteolytic (corpus luteum)
luteolytic (corpus luteum)
lux-s inhibitor (s-ribosylhomocysteinase)
lxr-a agonist (liver-x receptor)
lxr-b agonist (liver-x receptor-b)
acly inhibitor (atp-citrate lyase)
cbl inhibitor (cystathionine-b-lyase)
diagnostic aid: lymphangiography
anti-neoplastic (acute lymphoblastic leukemia, all)
anti-leukemic (lymphoblasts)
lymphocyte/leukocyte function assoc. antigen antagonist (lfa-1)
lymphocyte-specific kinase inhibitor (lck)
lck sh2 inhibitor (lymphocyte-specific protein tyrosine kinase)
anti-neoplastic (cll chronic lymphocytic leukemia)
anti-neoplastic (hiv lymphoid)
ptpn-22 inhibitor (lymphoid tyrosine phosphatase, lyp)
anti-neoplastic (burkitt's b-cell lymphoma)
anti-neoplastic (non-hodgkin lymphoma)
anti-neoplastic (ptcl, peripheral t-cell lymphoma)
anti-neoplastic (mantle cell lymphoma)
anti-neoplastic (lymphoma el-4)
alk inhibition (anaplastic lymphoma kinase)
ptpn-22 inhibitor (lymphoid tyrosine phosphatase, lyp)
mlr inhibitor (mixed lyphocyte reaction)
lysergic acid antagonist
brd ligand (bromodomain acetyl-lysine)
mbt antagonist (methyl-lysine binding protein)
kdm2/7 inhibitor (histone lysine demethylase)
lysine methyl-transferase g9a inhibitor
lsd-1 inhibitor (lysine specific demethylase)
jcl inhibitor (jurkat cell lysis)
lpa-1 antagonist (lysophosphatidic acid)
endosomal/lysosomal labile iron probe
lsd treatment (lysosomal storage disease)
pfa-m1 inhibitor (malarial metalloaminopeptidase)
m1 muscarinic agonist
m1 muscarinic antagonist
muscarinic m2 binder
m2 muscarinic agonist
m2 muscarinic antagonist
m2 muscarinic antagonist (cardioselective)
m3 muscarinic agonist
m3 muscarinic antagonist
m4 muscarinic agonist
m4 muscarinic antagonist
m5 muscarinic antagonist
mach4 agonist (muscarinic-4 acetylcholine)
muscarinic-3 acetylcholine antagonist (machr-3)
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
mif (macrophage migration inhibitory factor)
anti-amd (age related macular degeneration)
magl inhibitor (monoacylglycerol lipase)
anti-viral (polio t1 maheney)
tranquilizer (major)
cd4-mhc binding inhibitor (major histocompatability complex)
malaria prophylactic
anti-malarial
plasmepsin-1 inhibitor (malarial)
plasmepsin ii inhibitor (malarial)
anti-malarial (liver stage)
pfa-m1 inhibitor (malarial metalloaminopeptidase)
malate dehydrogenase inhibitor (ec 1.1.1.37)
reproductive toxicity (ca prop. 65, male)
contraceptive (male)
fab-d inhibitor (malonyl co-a acyl carrier)
mcd inhibitor (malonyl-coa decarboxylase, ec 4.1.1.9)
mtor c1/c2 inhibitor (mamalian target of rapamycin)
amcase inhibitor (acidic mammalian chitinase, ec 3.2.1.14)
mst-1 kinase inhibitor (mammalian sterile-20)
mtor inhibitor (mammalian target of rapamycin)
maspin inducer (mammary serine protease)
bipolar treatment (manic depression)
pancreatic cell manipulator
hlda inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlde inhibitor (glycero-manno-heptose-7-phosphate kinase)
anti-neoplastic (mantle cell lymphoma)
mao-a inhibitor (monamine oxidase)
mao-b inhibitor (monamine oxidase, ec 1.4.3.4)
mao inhibitor (ec 1.4.3.4)
mitogen-activated protein kinase inhibitor (p38-map)
dlk,map3k12 inhibitor (dual leucine zippper kinase)
map4k2 inhibitor (mitogen-activated protein kinase)
map4k4 inhibitor (mitogen-activated kinase, hgk)
erk-5 inhibitor (extracellular signal-regulated kinase, mapk-7)
anti-filovirus ebola/marburg
alkaloid-like (marine/animal)
marine toxin/metabolite (algal/sponge/fish)
mrg-x1 antagonist (mas-related genes)
bitter flavor masker
maspin inducer (mammary serine protease)
fto inhibitor (fatty mass & obesity assoc. protein)
mast cell activation inhibitor
cyclical mastalgia treatment
matriptase-2 inhibitor
matriptase inhibitor
mmp-1 inhibitor (matrix metalloproteinase-1)
mmp-10 inhibitor (matrix metalloproteinase-10)
mmp-11 inhibitor (matrix metalloproteinase-11)
mmp-12 inhibitor (matrix metalloproteinase-12)
mmp-13 inhibitor (matrix metalloproteinase-13)
mmp-14 inhibitor (matrix metalloproteinase-14)
mmp-15 inhibitor (matrix metalloproteinase-15)
mmp-16 inhibitor (matrix metalloproteinase-16)
mmp-17 inhibitor (matrix metalloproteinase-17)
mmp-2 inhibitor (matrix metalloproteinase-2, gelatinase-a)
mmp-20 inhibitor (matrix metalloproteinase-20)
mmp-26 inhibitor (matrix metalloproteinase-26)
mmp-3 inhibitor (matrix metalloproteinase-3)
mmp-7 inhibitor (matrix metalloproteinase-7)
mmp-8 inhibitor (matrix metalloproteinase-8)
mmp-9 inhibitor (matrix metalloproteinase-9, gelatinase-b)
hiv-1 maturation inhibitor
c-myc-max heterodimer disruptor
anti-neoplastic mb (medulloblastoma)
mbt antagonist (methyl-lysine binding protein)
melanocortin-4 agonist (mc-4)
melanocortin-4 antagonist (mc-4)
mcd inhibitor (malonyl-coa decarboxylase, ec 4.1.1.9)
melanin concentrating hormone inhibitor (mch-1)
mcl-1 inhibitor (myeloid cell leukemia)
mesangial cell proliferaton inhibitor (mcp)
mct-1 blocker (monocarboxylate transporter-1)
adam-10 inhibitor (adamalysin, mdc)
mdm2-p53 disruptors
anti-bacterial (mycobacterium tuberculosis, mdr)
anti-bacterial synergist (mdr)
anti-neoplastic (placlitaxel/mdr resistant)
multi-drug resistance inhibitor/extruder (mdr1, mrp1)
mds treatment (myelodisplastic syndrome)
mglur7 antagonist (meabotropic glutamate)
mglur4 agonist (meabotropic glutamate)
meallo-beta-lactamase inhibitors
anti-viral measles (paramyxovirus)
mechanistic hop
fimh antagonist (fimbrae-mediated bacterial adhesion)
mediates uptake blood to liver (hepatocytes)
anti-neoplastic mb (medulloblastoma)
mek1/2 inhibitor
melanin concentrating hormone inhibitor (mch-1)
depigmentor (melanine synthesis inhibitor)
melanocortin-1 antagonist
melanocortin-4 agonist (mc-4)
melanocortin-4 antagonist (mc-4)
anti-neoplastic (melanoma)
melanoma imaging
trpm8 antagonist (transient receptor potential melastatin)
melatonin-1 agonist (mt-1)
melatonin-1 antagonist (mt-1)
melatonin-2 agonist (mt-2)
melatonin-2 antagonist (mt-2)
melatonin-4 agonist
melatonin binder
prostate specific membrane antigen inhibitor (psma)
carbonic anhydrase-9 inhibitor (membrane-assoc., ec 4.2.1.1)
pgp overexpression inhibitor (plasma membrane glycoprotein)
mmpl-3 inhibitor (mycobacterial membrane large)
memory enhancer
meniere's disease treatment
mml1-menin interaction blocker
anti-bacterial (neisseria meningitidis gram-)
anti-menopause
anti-fungal (trichophyton mentagrophytes)
psychotropic (mental modifier)
mer-rtk inhibitor (receptor tyrosine kinase)
mesangial cell proliferaton inhibitor (mcp)
anti-neoplastic (pleural mesothelioma)
pfbkfb3 inhibitor (metabolic kinase)
metabolic syndrome treatment
elimination rate (metabolism excretion)
drug metabolism inhibitor
active metabolite
anti-metabolite
significant metabolite
marine toxin/metabolite (algal/sponge/fish)
mglur1 imager (metabotropic glutamate)
mglur5 agonist (metabotropic glutamate)
mglur2 agonist (metabotropic glutamate)
mglur3 agonist (metabotropic glutamate)
mglur5 antagonist (metabotropic glutamate)
mglur1 antagonist competitive (metabotropic glutamate)
mglur3 antagonist (metabotropic glutamate)
mglur2 modulator (metabotropic glutamate)
mglur agonist (metabotropic glutamate receptor)
mglur antagonist (metabotropic glutamate receptor)
p2y-11 receptor agonist (purine metabromic)
metacestocide (tape worm)
metal chelator
pfa-m1 inhibitor (malarial metalloaminopeptidase)
metalloelastase inhibitor
metap inhibitor (e. coli metalloproteinase)
mmp-1 inhibitor (matrix metalloproteinase-1)
mmp-10 inhibitor (matrix metalloproteinase-10)
mmp-11 inhibitor (matrix metalloproteinase-11)
mmp-12 inhibitor (matrix metalloproteinase-12)
mmp-13 inhibitor (matrix metalloproteinase-13)
mmp-14 inhibitor (matrix metalloproteinase-14)
mmp-15 inhibitor (matrix metalloproteinase-15)
mmp-16 inhibitor (matrix metalloproteinase-16)
mmp-17 inhibitor (matrix metalloproteinase-17)
mmp-2 inhibitor (matrix metalloproteinase-2, gelatinase-a)
mmp-20 inhibitor (matrix metalloproteinase-20)
mmp-26 inhibitor (matrix metalloproteinase-26)
mmp-3 inhibitor (matrix metalloproteinase-3)
mmp-7 inhibitor (matrix metalloproteinase-7)
mmp-8 inhibitor (matrix metalloproteinase-8)
mmp-9 inhibitor (matrix metalloproteinase-9, gelatinase-b)
metallothionein synthesis inhibitor
metap-1 inhibitor (methionine aminopeptidase)
metap-2 inhibitor (methionine aminopeptidase)
metap inhibitor (e. coli metalloproteinase)
metastasis inhibitor
anti-addictive (cocaine, opiates, methamphetamine, etc.)
antidote glycol methanol poisoning
anti-methemoglobinemic
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
metap-2 inhibitor (methionine aminopeptidase)
metap-1 inhibitor (methionine aminopeptidase)
methionine antagonist
methionyl t-rna synthetase inhibitor
methuosis inducer (cell death)
nmda agonist (n-methyl-d-aspartate)
nmda blocker (n-methyl-d-aspartate)
nmda antagonist (n-methyl-d-aspartate)
nmda antagonist (n-methyl-d-aspartate, competitive)
mbt antagonist (methyl-lysine binding protein)
prmt-1 inhibitor (protein arginine methyl-transferase)
hmt-dot1l inhibitor (histone methyl transferase)
comt inhibitor (catechol-o-methyl-transferase, ec 2.1.1.6)
lysine methyl-transferase g9a inhibitor
histamine n-methyl-transferase inhibitor
phenylethanolamine methyl-transferase inhibitor (pnmt, ec 2.1.1.28)
pme-1 inhibitor (protein phosphatase methylesterase)
mgmt inhibitor (methylguanine-dna methyltransferase)
dnmt inhibitor (dna methyltransferase)
prmt-3 inhibitor (protein methyltransferase)
trmd inhibitor (t-rna-n1-g37 methyltransferase)
mgmt inhibitor (methylguanine-dna methyltransferase)
monoacylglycerol lipase inhibitor (mgl)
mglur agonist (metabotropic glutamate receptor)
mglur antagonist (metabotropic glutamate receptor)
mglur1 antagonist competitive (metabotropic glutamate)
mglur1 imager (metabotropic glutamate)
mglur2 agonist (metabotropic glutamate)
mglur2 modulator (metabotropic glutamate)
mglur3 agonist (metabotropic glutamate)
mglur3 antagonist (metabotropic glutamate)
mglur4 agonist (meabotropic glutamate)
mglur5 agonist (metabotropic glutamate)
mglur5 antagonist (metabotropic glutamate)
mglur7 antagonist (meabotropic glutamate)
mgmt inhibitor (methylguanine-dna methyltransferase)
cd4-mhc binding inhibitor (major histocompatability complex)
low toxicity to mice or fibroblast cells
mptp-b inhibitor (microbacterium tyrosine phosphatase)
anti-microbial
microbial lipase inhibitor
anti-microbial topical
anti-microbial (veterinary)
anti-bacterial (micrococcus aureus gram+)
mpges-1 inhibitor (microsomal prostaglandin e2 synthase)
microsomal triglyceride transfer protein (mtp) inhibitor
anti-fungal (microsporum canis)
microtox super-active
microtox tested (toxicity)
microtubule destabilizer
microtubule stabilizer (binder, tubulin inhibitor)
mif (macrophage migration inhibitory factor)
anti-migrane
neutrophil migration blocker
mif (macrophage migration inhibitory factor)
anti-fungal (barley mildew)
anti-fungal (powdery mildew)
oxygen mimetic
beta turn mimetic
gaba mimetic (gamma amino butyric acid)
smac activator mimetic (second mitochondria activator caspases)
insulin mimic (modulator)
no attenuated mimic (nitric oxide)
mineralocorticoid (aldosterone) antagonist
mineralocorticoid (na retention, k loss)
tranquilizer (minor)
dna minor groove binder
miotic (pupil contraction)
dyrk-1b (dual-specificity tyrosine kinase, mirk)
anti-prion (tse, cjd, scrapie, misfolded protein)
acaricide (ticks mites)
insecticide (red mites)
smac activator mimetic (second mitochondria activator caspases)
mitochondria stabilizer
acc2 inhibitor (acetyl coa carboxylase-2, mitochondrial)
mitochondrial dye
mitochondrial electron transport complex i inhibitor
mitochondrial electron transport complex ii inhibitor
mitochondrial electron transport complex iii (qi) inhibitor
mitochondrial electron transport complex iv inhibitor
mptp inhibitor (mitochondrial permeability transition pore)
mitochondrial thymidine kinase inhibitor (tk-2)
mitochondrial toxicant
mnk-1 inhibitor (mitogen-activated kinase)
mnk/ar degrader (mitogen-activated kinase & androgen receptor)
map4k4 inhibitor (mitogen-activated kinase, hgk)
map4k2 inhibitor (mitogen-activated protein kinase)
mitogen-activated protein kinase inhibitor (p38-map)
mkp-1 inhibitor (mitogen activated protein kinase phosphatase)
mitogen stress response kinase inhibitor(msk-1)
mitogenic (mitosis)
mitogenic (mitosis)
mitotic catastrophant
eg5 inhibitor (mitotic kinesin)
anti-mitotic (suppresses cell division)
mlk-1 inhibitor (mixed-lineage kinase-1)
mlk-2 inhibitor (mixed-lineage kinase-2)
mlk-3 inhibitor (mixed-lineage kinase-3)
mll inhibition (mixed lineage leukemias)
mlr inhibitor (mixed lyphocyte reaction)
mkp-1 inhibitor (mitogen activated protein kinase phosphatase)
mlk-1 inhibitor (mixed-lineage kinase-1)
mlk-2 inhibitor (mixed-lineage kinase-2)
mlk-3 inhibitor (mixed-lineage kinase-3)
mll inhibition (mixed lineage leukemias)
mlr inhibitor (mixed lyphocyte reaction)
mml1-menin interaction blocker
mmp-1 inhibitor (matrix metalloproteinase-1)
mmp-10 inhibitor (matrix metalloproteinase-10)
mmp-11 inhibitor (matrix metalloproteinase-11)
mmp-12 inhibitor (matrix metalloproteinase-12)
mmp-13 inhibitor (matrix metalloproteinase-13)
mmp-14 inhibitor (matrix metalloproteinase-14)
mmp-15 inhibitor (matrix metalloproteinase-15)
mmp-16 inhibitor (matrix metalloproteinase-16)
mmp-17 inhibitor (matrix metalloproteinase-17)
mmp-2 inhibitor (matrix metalloproteinase-2, gelatinase-a)
mmp-20 inhibitor (matrix metalloproteinase-20)
mmp-26 inhibitor (matrix metalloproteinase-26)
mmp-3 inhibitor (matrix metalloproteinase-3)
mmp-7 inhibitor (matrix metalloproteinase-7)
mmp-8 inhibitor (matrix metalloproteinase-8)
mmp-9 inhibitor (matrix metalloproteinase-9, gelatinase-b)
mmpl-3 inhibitor (mycobacterial membrane large)
mnk-1 inhibitor (mitogen-activated kinase)
mnk/ar degrader (mitogen-activated kinase & androgen receptor)
blood stem cell mobilization agent
mock-infected mt4 cell toxicity
aph3'-iiia inhibitor (aminoglycoside modifying enzyme)
ik/sk potassium channel modulators
vcam-1 inhibitor (vascular cell adhesion molecule)
moleuclar tong
molluscicide
molluscicide (biomphalaria glabrata)
mao-a inhibitor (monamine oxidase)
mao-b inhibitor (monamine oxidase, ec 1.4.3.4)
cognition dysfunction monitor
magl inhibitor (monoacylglycerol lipase)
monoacylglycerol lipase inhibitor (mgl)
vmat-2 inhibitor (vesicular monoamine transporter)
mct-1 blocker (monocarboxylate transporter-1)
anti-neoplastic (acute monocytic leukemia)
kmo inhibitor (kynurenine-3- monooxygenase)(ec1.14.13.9)
inositol monophosphatase inhibitor
ampk activator (adenosine monophosphate activated kinase)
adenosine monophosphate deaminase (ampda, ec 3.5.4.6)
odcase inhibitor (orotidine 5'-monophosphate decarboxylase, ec 4.1.1.23)
inosine-5'-monophosphate dehydrogenase inhibitor (impdh)
tmpk inhibitor (thymidine monophosphate kinase)
gmp guanosine monophosphate synthase inhibitor
mps-1 inhibitor (monopolar spindle, ttk)
mood regulator
mu opioid agonist (mor-1 6tm/e11)
anti-bacterial (moraxella catarrhalis gram-)
morphine antagonist
bmp-2 stimulator (bone morphogenic protein)
bmp-6 inhibitor (bone morphogenic protein)
insecticide (mosquito adult)
insecticide (mosquito larvae)
motilin agonist
motilin antagonist
carcinogen (rat, mouse)
carcinogen (mouse liver)
anti-xerostomia (dry mouth)
mpges-1 inhibitor (microsomal prostaglandin e2 synthase)
mpo inhibitor (myeloperoxidase, ec 1.11.2.2)
parkinsonism inducer (as mpp+)
mps-1 inhibitor (monopolar spindle, ttk)
mptp-b inhibitor (microbacterium tyrosine phosphatase)
mptp inhibitor (mitochondrial permeability transition pore)
mrg-x1 antagonist (mas-related genes)
mri probe
multi-drug resistance inhibitor/extruder (mdr1, mrp1)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
ms (multiple sclerosis) treatment
mitogen stress response kinase inhibitor(msk-1)
mst-1 kinase inhibitor (mammalian sterile-20)
melatonin-1 agonist (mt-1)
melatonin-1 antagonist (mt-1)
melatonin-2 antagonist (mt-2)
melatonin-2 agonist (mt-2)
mock-infected mt4 cell toxicity
sah-mta nucleosidase inhibitor
mtor activator
mtor c1/c2 inhibitor (mamalian target of rapamycin)
mtor inhibitor (mammalian target of rapamycin)
microsomal triglyceride transfer protein (mtp) inhibitor
calpain mu (i) inhibitor
mu opioid agonist
mu opioid agonist (mor-1 6tm/e11)
mu opioid antagonist
mu opioid binder
mucolytic
mucosal protectant
multi-drug resistance inhibitor/extruder (mdr1, mrp1)
anti-neoplastic (multiple myeloma)
ms (multiple sclerosis) treatment
mur-a inhibitor (bacterial transferase)
mur-b inhibitor (udp-ep-glu-nac reductase)
mur-d ligase inhibitor (glutamic acid)
glutamate racemase (muri)
muscarinic
muscarinic-3 acetylcholine antagonist (machr-3)
mach4 agonist (muscarinic-4 acetylcholine)
muscarinic acetylcholine-5 agonist (achr-5)
m3 muscarinic agonist
m4 muscarinic agonist
m1 muscarinic agonist
m2 muscarinic agonist
muscarinic agonist
m4 muscarinic antagonist
m5 muscarinic antagonist
m1 muscarinic antagonist
muscarinic antagonist
m2 muscarinic antagonist
m3 muscarinic antagonist
m2 muscarinic antagonist (cardioselective)
muscarinic m2 binder
muscle atrophy treatment
smooth muscle contractant
negative inotrope (weakens muscle contraction)
positive inotrope (strengthen muscle contraction)
skeletal muscle relaxant
muscle relaxant
smooth muscle relaxant
muscle relaxant (short duration)
muscle relaxant (veterinary)
uterotonic (uterus muscle tone)
treatment for muscular dystrophy
musk odorant
sulfur mustard degredation product
mutagen (ames test carcinogen suspect)
ames test negative (non-mutagenic)
non-mutagenic (likely)
anti-bacterial (streptococcus mutans gram+)
bcr-abl and t315i-mutant kinase inhibitor
mutant sod-1 anti-aggregant (superoxide dismutase)
gene repair of nonsense mutation damage
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
diagnostic aid: myasthenia gravis
anti-myasthenic
c-myc-max heterodimer disruptor
anti-bacterial (mycobacteria)
mmpl-3 inhibitor (mycobacterial membrane large)
anti-bacterial (mycobacterium avium gram+)
anti-bacterial (mycobacterium kansasii gram+)
anti-bacterial (mycobacterium tuberculosis)
anti-bacterial (mycobacterium tuberculosis, mdr)
anti-fungal (anti-mycotic)
mycotoxin
myd-88 inhibitor (myeloid differentiation protein)
mydriatic (dilates pupils)
mds treatment (myelodisplastic syndrome)
myelofibrosis treatment
anti-neoplastic (myeloma myelogenous)
anti-neoplastic (acute myelogenous leukemia, aml)
mcl-1 inhibitor (myeloid cell leukemia)
myd-88 inhibitor (myeloid differentiation protein)
chronic myeloid leukemia (cml) treatment
anti-neoplastic (multiple myeloma)
anti-neoplastic (myeloma myelogenous)
mpo inhibitor (myeloperoxidase, ec 1.11.2.2)
myocardial imaging
treatment for myocardial infarction or perfusion injury
anabolic (myotrophic)
n-myristoyl transferase inhibitor (nmt)
n-acetyl-aspartyl-glutamate peptidase inhibitor (naag)
n-myristoyl transferase inhibitor (nmt)
n-type voltage gated calcium channel blocker (vgcc, vdcc)
glu-n1/2a nmda receptor inhibitor
nmda ligand (glu-n1/2b selective)
trmd inhibitor (t-rna-n1-g37 methyltransferase)
na-h5n1 inhibitor (neuramidase h5n1)
neuraminidase na inhibitor
mineralocorticoid (na retention, k loss)
saluretic (na+, cl- excretion)
naaa inhibitor (n-acylethanolamine acid amidase)
n-acetyl-aspartyl-glutamate peptidase inhibitor (naag)
neuropeptidase naaladase inhibitor
mur-b inhibitor (udp-ep-glu-nac reductase)
nicotinic acetylcholine agonist (nachr)
nicotinic acetylcholine antagonist (nachr)
nicotinic-acetylcholine binder, partial agonist (nachr)
nicotinic acetylcholine inhibitor (nachr-7)
nicotinic acetylcholine-7 agonist (nachr-7)
nicotinic acetylcholine antagonist (nachr-a2b2)
nicotinic acetylcholine agonist (nachr a3/b2)
nicotinic acetylcholine a3b4 antagonist (nachr a3b4)
nicotinic acetylcholine partial agonist (nachr-a4/b2)
nad glycohydrase inhibitor
nad glycohydrolase inhibitor
nqo2 inhibitor (nad quinone oxidoreductase, ec 1.10.99.2)
nqo1 inhibitor (nad quinone oxidoreductase, ec 1.6.99.2)
nad synthetase inhibitor (nicotinamide adenine dinucleotide)
nox-1 inhibitor (nadph oxidase-1)
nox-4 inhibitor (nadph oxidase-4)
nafld treatment (non-alcoholic fatty liver disease)
allosteric inhibitor (nam)
nampt inhibitor (nicotinamide phosphororibosyltransferase)
anti-narcoleptic (eugeroic)
narcotic
anti-addictive (narcotic antagonist)
anti-addictive (alcohol/narcotic antagonist)
anti-addictive (alcohol/narcotic aversion therapy)
narcotic (short acting)
vasodilator (nasal)
nasal decongestant
anti-neoplastic (nasopharynx)
natriuretic (sodium excretion)
triterpene natural product
anti-emetic (anti-nauseant)
sodium channel nav1.3 modulator
sodium channel nav1.4 blocker
sodium channel nav1.7 modulator
sodium channel nav1.8 modulator
hiv-nucleocapsid binder (nc)
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
anti-neoplastic (active over nci cell panel)
ncx reverse inhibitor (sodium/calcium)
ndri inhibitor (norepinephrine dopamine reuptake)
necroptosis inducer
necroptosis inhibitor
tumor necrosis factor blocker (tnf-a, tace, adam-17)
tnbc treatment (triple-negative breast cancer)
negative chronotropic (decrease heart rate)
negative inotrope (weakens muscle contraction)
ames test negative (non-mutagenic)
anti-bacterial (neisseria meningitidis gram-)
nek2/hec1 inhibitor
nematocide
anthelmintic (nematode)
anti-fungal (cryptoformans neoformans)
anti-neoplastic
anti-neoplastic (active over nci cell panel)
anti-neoplastic (acute lymphoblastic leukemia, all)
anti-neoplastic (acute monocytic leukemia)
anti-neoplastic (acute myelogenous leukemia, aml)
anti-neoplastic (adenocarcinoma)
anti-neoplastic (adjuvant)
anti-neoplastic (anti-cd-3)
anti-neoplastic (ascites abdominal)
anti-neoplastic (bladder)
anti-neoplastic (brain cerebral)
anti-neoplastic (breast)
anti-neoplastic (breast, hormone-dependent)
anti-neoplastic (burkitt's b-cell lymphoma)
anti-neoplastic (chemo-induced tumors)
anti-neoplastic (cll chronic lymphocytic leukemia)
anti-neoplastic (cns, neuroblastoma)
anti-neoplastic (colorectal)
anti-neoplastic (epidermal)
anti-neoplastic (erythroleukemia)
anti-neoplastic (esophagus)
anti-neoplastic (fibrosarcoma)
anti-neoplastic (gastro-intestinal, gist)
anti-neoplastic (glioma)
anti-neoplastic (hct colon)
anti-neoplastic (hela cervical uterine endometrial)
anti-neoplastic (hepatic, liver)
anti-neoplastic (hiv lymphoid)
anti-neoplastic (hl-60 leukemia)
anti-neoplastic (jurkat leukemia)
anti-neoplastic (l-5178)
anti-neoplastic (leukemia l-1210)
anti-neoplastic (lung non-small cell, nsclc)
anti-neoplastic (lung small cell)
anti-neoplastic (lymphoma el-4)
anti-neoplastic (mantle cell lymphoma)
anti-neoplastic mb (medulloblastoma)
anti-neoplastic (melanoma)
anti-neoplastic (multiple myeloma)
anti-neoplastic (myeloma myelogenous)
anti-neoplastic (nasopharynx)
anti-neoplastic (non-hodgkin lymphoma)
anti-neoplastic (osteosarcoma, bone)
anti-neoplastic (ovarian)
anti-neoplastic (ovarian a2780r)
anti-neoplastic (p388 leukemia)
anti-neoplastic (pancreatic)
anti-neoplastic, peritoneal
anti-neoplastic (placlitaxel/mdr resistant)
anti-neoplastic (plasmocytoma)
anti-neoplastic (pleural mesothelioma)
anti-neoplastic (potentiator)
anti-neoplastic (prostate)
anti-neoplastic (ptcl, peripheral t-cell lymphoma)
anti-neoplastic (renal / kidney)
anti-neoplastic (sarcoma 180)
anti-neoplastic (skin basal cell bcc)
anti-neoplastic (solid tumors)
anti-neoplastic (squamous)
anti-neoplastic (taxane refractory)
anti-neoplastic (teratocarcinoma)
anti-neoplastic (testicular)
anti-neoplastic (thyroid)
anti-neoplastic (topical)
anti-neoplastic (walker 256)
anti-nephritic
nerve gas prophylactic
organophosphate nerve gas reactivator (ache, bche)
ngf agonist (nerve growth factor)
nerve growth factor activator
nerve growth factor inhibitor
noradrenaline/norepinephrine transport inhibitor (net)
anesthetic (neuralgia)
anti-neuralgic
na-h5n1 inhibitor (neuramidase h5n1)
neuraminidase na inhibitor
anti-neuritic
neuritogenic
anti-neoplastic (cns, neuroblastoma)
nft binder (neurofibriallary tangle)
neurogenic
neuroinflammation treatment
nk2 neurokinin agonist
nk1 neurokinin antagonist
nk4 neurokinin antagonist
nk2 neurokinin antagonist
nk3 neurokinin antagonist
anti-psychotic (neuroleptic)
nmur-2 agonist (neuromedin)
nmur-1 agonist (neuromedin)
neuromedin b antagonist
neuromodulator
neuromuscular blocker
neuromuscular toxicant
neuronal nitric oxide synthase inhibitor (nnos)
anti-diabetic neuropathy
neuropathy target esterase inhibitor (nte)
peripheral neuropathy treatment
neuropeptidase naaladase inhibitor
nff1-agonist (neuropeptide)
nff1-antagonist (neuropeptide)
nff2-antagonist (neuropeptide)
npff ligand (neuropeptide ff)
npsr antagonist (neuropeptide-s receptor)
npy-1 antagonist (neuropeptide-y1)
npy-5 antagonist (neuropeptide-y5)
neuroprotectant
nts-2 agonist (neurotensin)
neurotensin antagonist
cardiotoxic and/or neurotoxic
neurotoxin
insect neurotoxin
frog neurotoxin
bonta inhibitor (botulinum neurotoxin-a)
neurotransmitter
tnk-1 antagonist (tachykinin neurotransmitter-1)
tnk2 antagonist (tachykinin neurotransmitter-2)
tnk-3 antagonist (tachykinin neurotransmitter-3)
tnk-3 agonist (tachykinin neurotransmitter-3)
neurotrophic
anti-viral (neurotropic, alpha)
nvp-3cl inhibitor (neurovirus peptidase)
boron neutron capture therapy (bnct)
anti-neutropenia (lack of neutrophils)
neutrophil activator
human neutrophil elastase inhibitor
neutrophil elastase inhibitor (ec 3.4.21.37)
neutrophil migration blocker
anti-neutropenia (lack of neutrophils)
nuclear factor kappa b inhibitor (nf-k-b)
nff1-agonist (neuropeptide)
nff1-antagonist (neuropeptide)
nff2-antagonist (neuropeptide)
nft binder (neurofibriallary tangle)
ngf agonist (nerve growth factor)
sodium-hydrogen exchange inhibitor (nhe-1)
gpcr-109a agonist (g-protein coupled, niacin-109a)
niacin-109a receptor agonist
nad synthetase inhibitor (nicotinamide adenine dinucleotide)
nampt inhibitor (nicotinamide phosphororibosyltransferase)
1heh inhibitor (nicotinamide ribose kinase)
anti-addictive (nicotine, smoking cessation)
nicotinic a4b2 agonist
nicotinic acetylcholine-7 agonist (nachr-7)
nicotinic acetylcholine a3b4 antagonist (nachr a3b4)
nicotinic acetylcholine agonist (nachr)
nicotinic acetylcholine agonist (nachr a3/b2)
nicotinic acetylcholine antagonist (nachr)
nicotinic acetylcholine antagonist (nachr-a2b2)
nicotinic-acetylcholine binder, partial agonist (nachr)
nicotinic acetylcholine inhibitor (nachr-7)
nicotinic acetylcholine partial agonist (nachr-a4/b2)
nicotinic antagonist
anti-fungal (aspergillus niger)
anti-viral (west nile)
anti-viral (flavivirus, dengue, west nile)
no attenuated mimic (nitric oxide)
nitric oxide donor
nitric oxide scavenger
inducible nitric oxide synthase inhibitor (inos)
neuronal nitric oxide synthase inhibitor (nnos)
nitric oxide synthase inhibitor (nos, ec 1.14.13.39)
nitrification inhibitor
nitrification inhibitor (soil)
activated by ddn (deazaflavin-dependent nitroreductase)
nitroxyl donor
nk1 neurokinin antagonist
nk2 neurokinin agonist
nk2 neurokinin antagonist
nk3 neurokinin antagonist
nk4 neurokinin antagonist
nmda agonist (n-methyl-d-aspartate)
nmda antagonist (n-methyl-d-aspartate)
nmda antagonist (n-methyl-d-aspartate, competitive)
nmda antagonist (nr2a/b selective)
nmda antagonist (nr2c/d selective)
nmda blocker (n-methyl-d-aspartate)
psd-95/nmda inhibitor
nmda ligand (glu-n1/2b selective)
glu-n1/2a nmda receptor inhibitor
n-myristoyl transferase inhibitor (nmt)
nmur-1 agonist (neuromedin)
nmur-2 agonist (neuromedin)
neuronal nitric oxide synthase inhibitor (nnos)
nociceptin nop agonist
nociceptin nop antagonist
analgesic (anti-nociceptive)
nafld treatment (non-alcoholic fatty liver disease)
autophagy inducer (non-apoptosis)
anti-neoplastic (non-hodgkin lymphoma)
dna binder (non-intercalating)
ph indicator, non-invasive
ames test negative (non-mutagenic)
non-mutagenic (likely)
non-nutritive sweetener
blood-brain non-penetrant (relatively bbb-)
renin inhibitor (non-peptide)
anti-bacterial (tuberculosis,dormant,non-replicating)
anxiolytic (non-sedating)
anti-histamine (non-sedating)
anti-neoplastic (lung non-small cell, nsclc)
synergist (non-specific)
anti-inflammatory non-steroidal (nsaid)
gene repair of nonsense mutation damage
nootropic (cerebral stimulant)
nociceptin nop agonist
nociceptin nop antagonist
nop binder (opiate-like)
noradrenaline/norepinephrine transport inhibitor (net)
noradrenergic-a2
triple reuptake inhibitor (serotonin, norepinephrine, dopamine)
ndri inhibitor (norepinephrine dopamine reuptake)
norepinephrine reuptake inhibitor (nri)
serotonin-norepinephrine reuptake inhibitor (snri)
noradrenaline/norepinephrine transport inhibitor (net)
nitric oxide synthase inhibitor (nos, ec 1.14.13.39)
nps inhibitor (notch protein signaling)
notch sparing
nox-1 inhibitor (nadph oxidase-1)
nox-4 inhibitor (nadph oxidase-4)
npff ligand (neuropeptide ff)
npp-1 inhibitor (nucleotide pyrophosphate/phosphodiesterase-1)
nps inhibitor (notch protein signaling)
npsr antagonist (neuropeptide-s receptor)
npy-1 antagonist (neuropeptide-y1)
npy-5 antagonist (neuropeptide-y5)
nqo1 inhibitor (nad quinone oxidoreductase, ec 1.6.99.2)
nqo2 inhibitor (nad quinone oxidoreductase, ec 1.10.99.2)
nmda antagonist (nr2a/b selective)
nmda antagonist (nr2c/d selective)
nrf-2 activator (nuclear factor erythroid)
nrf2 activator (keap-1 modifier)
norepinephrine reuptake inhibitor (nri)
dengue 2 ns2b protease inhibitor
hcv-ns3 protease inhibitor (hepatitis c)
hcv-ns4a inhibitor (hepatitis c)
hcv-ns4b inhibitor (hepatitis c)
hcv-ns5a inhibitor (hepatitis c)
hcv-ns5b rna polymerase inhibitor (hepatitis c)
anti-inflammatory non-steroidal (nsaid)
anti-neoplastic (lung non-small cell, nsclc)
neuropathy target esterase inhibitor (nte)
nts-2 agonist (neurotensin)
nrf-2 activator (nuclear factor erythroid)
nuclear factor kappa b inhibitor (nf-k-b)
rorgt antagonist (nuclear hormone receptor gamma)
hiv-nucleocapsid binder (nc)
sah-mta nucleosidase inhibitor
p2x4 antagonist (purine nucleoside)
hcn-1 blocker (hyperpolarization-activated cyclic nucleoside-gated)
hcn-2 blocker (hyperpolarization-activated cyclic nucleoside-gated)
purine nucleoside phosphorylase inhibitor (pnp, ec 2.4.2.1)
nucleoside transport inhibitor
p2y12 antagonist (purine, nucleotide)
p2y-2 agonist (purine, nucleotide)
p2y-4 agonist (purine, nucleotide)
p2y-6 agonist (purine, nucleotide)
p2y1 agonist (purine, nucleotide)
cng antagonist (cyclic nucleotide-gated channel)
npp-1 inhibitor (nucleotide pyrophosphate/phosphodiesterase-1)
nutrient
nutrition aid: vitamin b deficiency
nutritional factor
non-nutritive sweetener
nvp-3cl inhibitor (neurovirus peptidase)
lesch-nyhan treatment
nystagmus inhibitor
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
o-glc-ncase inhibitor (o-linked glucose-n-acetyl)
urinary incontinence (dysuria, overactive bladder, oab)
oatp1-b1 inhibitor (organic anion transporting polypeptide)
oatp1-b3 inhibitor (organic anion transporting polypeptide)
oatp2-b1 inhibitor (organic anion transporting polypeptide)
anti-obesity
fto inhibitor (fatty mass & obesity assoc. protein)
ocpd treatment (obsessive compulsive personality)
diagnostic aid: obstetrics
anti-copd (chronic obstructive pulmonary disease)
anti-occlusion peripheral arteries
ocpd treatment (obsessive compulsive personality)
octopamine agonist
odcase inhibitor (orotidine 5'-monophosphate decarboxylase, ec 4.1.1.23)
musk odorant
terpine (often toxic/irritant)
pep/pop inhibitor (prolylendopeptidase/prolyl oligopeptidase)
prep inhibitor (prolyl oligopeptidase, ec 3.4.21.26)
pim-1 kinase inhibitor (proto-oncogene)
anti-cholinergic (ophthalmic)
anesthetic (ophthalmic)
anti-viral (ophthalmic)
anti-bacterial (ophthalmic)
ophthalmic adrenergic
ophthalmic (anti-oxidant)
ophthalmic cholinergic
ophthalmic hypotensive
anti-inflammatory (ophthalmic-topical)
opiate
nop binder (opiate-like)
anti-addictive (cocaine, opiates, methamphetamine, etc.)
dcx-1 opioid agonist
dcx-2 opioid agonist
k2-b opioid agonist
delta opioid agonist
mu opioid agonist
mu opioid agonist (mor-1 6tm/e11)
kappa opioid agonist (sedating)
mu opioid antagonist
delta opioid antagonist
kappa opioid antagonist
opioid antagonist
mu opioid binder
opioid-like antagonist (orli-1)
slos treatment (smith-lemli-opitz syndrome)
p-gp efflux optimized (p-glycoprotein)
herg channel optimized (qt interval decreased)
appetite stimulant (orexigenic)
ox-1 antagonist (orexin-1)
ox-2 antagonist (orexin-2)
oatp1-b1 inhibitor (organic anion transporting polypeptide)
oatp1-b3 inhibitor (organic anion transporting polypeptide)
oatp2-b1 inhibitor (organic anion transporting polypeptide)
organophosphate nerve gas reactivator (ache, bche)
opioid-like antagonist (orli-1)
ornithine decarboxylase inhibitor (ec 4.1.1.17)
odcase inhibitor (orotidine 5'-monophosphate decarboxylase, ec 4.1.1.23)
anti-viral orthopox (vaccinia/cow, smallpox)
anti-fungal (pyricularia oryzae)
fop (fibrodysplasia ossificans progressiva)
osteoarthritis treatment
bone resorption (osteoclast) inhibitor
anti-osteomylitic
anti-osteoporitic
anti-neoplastic (osteosarcoma, bone)
yoph inhibitor (yersinia outer protein phosphatase)
anti-neoplastic (ovarian)
anti-neoplastic (ovarian a2780r)
ovarian e2 secretion inhibitor
ovarian inhibitor (worker bees)
anti-neoplastic (active over nci cell panel)
urinary incontinence (dysuria, overactive bladder, oab)
pgp overexpression inhibitor (plasma membrane glycoprotein)
soicr suppressor (store-overloaded-induced calcium release)
ovulation inhibitor
ovulation stimulant
ox-1 antagonist (orexin-1)
ox-2 antagonist (orexin-2)
anti-oxidant
ophthalmic (anti-oxidant)
anti-oxidant (animal feed)
anti-oxidant (food)
anti-oxidant (lipid)
mao-a inhibitor (monamine oxidase)
nox-1 inhibitor (nadph oxidase-1)
nox-4 inhibitor (nadph oxidase-4)
mao-b inhibitor (monamine oxidase, ec 1.4.3.4)
ssao inhibitor (semicarbazide-sensitive amino oxidase, ec 1.4.3.6)
xanthine oxidase inhibitor
protoporphyrinogen oxidase inhibitor
d-amino acid oxidase inhibitor(daao)
oxidative phosphorylation uncoupler
no attenuated mimic (nitric oxide)
nitric oxide donor
nitric oxide scavenger
allene oxide synthase inhibitor (cyp-74)
inducible nitric oxide synthase inhibitor (inos)
neuronal nitric oxide synthase inhibitor (nnos)
nitric oxide synthase inhibitor (nos, ec 1.14.13.39)
nqo2 inhibitor (nad quinone oxidoreductase, ec 1.10.99.2)
nqo1 inhibitor (nad quinone oxidoreductase, ec 1.6.99.2)
2,3-oxidosqualene cyclase inhibitor (ec 5.4.99.7)
oxygen mimetic
kmo inhibitor (kynurenine-3 oxygenase)
heme oxygenase-1 inhibitor
anti-fungal (fusarium oxysporum)
abortifacient oxytocic
oxytocin agonist
oxytocin antagonist (tocolytic, delays labor)
p-cab (potassium-competitive acid blocker)
p-gp efflux high (p-glycoprotein)
p-gp efflux optimized (p-glycoprotein)
p-glycoprotein inhibitor (p-gp)
p-glycoprotein inhibitor (p-gp)
p-gp efflux high (p-glycoprotein)
p-gp efflux optimized (p-glycoprotein)
pfldh inhibitor (p.falciparum lactate dehydrogenase)
purinergic p2 antagonist
pak-4 inhibitor (p21-activated kinase)
p2x2 antagonist (purinergic)
purinergic antagonist (p2x3)
p2x4 antagonist (purine nucleoside)
purinergic p2x7 antagonist
p2y-11 receptor agonist (purine metabromic)
p2y-2 agonist (purine, nucleotide)
p2y-4 agonist (purine, nucleotide)
p2y-6 agonist (purine, nucleotide)
p2y1 agonist (purine, nucleotide)
p2y1 platelet antagonist
p2y12 antagonist (purine, nucleotide)
mitogen-activated protein kinase inhibitor (p38-map)
anti-neoplastic (p388 leukemia)
cytochrome p450 inducer (drug interaction?)
cytochrome p450 inducer (ethoxyresorufin o-deethylase)
cytochrome p450 inhibitor (cyp-11b1, corticosterone synthase)
cytochrome p450 inhibitor (cyp-11b2, aldosterone synthase)
cytochrome p450 inhibitor (cyp-17)
cytochrome p450 inhibitor (cyp-1a1)
cytochrome p450 inhibitor (cyp-26a)
cytochrome p450 inhibitor (cyp-2c8)
cytochrome p450 inhibitor (cyp-2c9)
cytochrome p450 inhibitor (cyp-2d6)
cytochrome p450 inhibitor (cyp-2d6 or cyp-2c19)
cytochrome p450 inhibitor (cyp-3a4, grapefruit effect)
cytochrome p450 inhibitor (cyp-51)
cytochrome p450 inhibitor (cyp1b1)(pah activator)
cytochrome p450 inhibitor (cyp2w1)
cytochrome p450 inhibitor (drug interaction?)
amyloidosis treatment (ttr, sodi, or p53)
mdm2-p53 disruptors
cytochrome p680 photosynthesis inhibitor (hill reaction)
hcv-p7 inhibitor (hepatitis c)
ledgf-p75 integrase blocker (lens epithelial-cell derived)
p97 inhibitor (vcp, valosine containing protein)
pad inhibitor (protein arginine deaminase)
platelet anti-aggregant (paf)
paf receptor binder
anti-paget's disease
anti-hypertensive (pulmonary, pah)
cytochrome p450 inhibitor (cyp1b1)(pah activator)
anti-fouling paint
pak-4 inhibitor (p21-activated kinase)
cpt-1a inhibitor (carnitine palmitoyl transferase)
cpt-1a activator (carnitine palmitoyl transferase)
anti-cerebral disease/injury/palsy
pam (positive allosteric modifier)
dub inhibitors (deubiquitinating enzymes, pan)
pan-selectin antagonist (p-selectin)
dpb treatment (diffuse panbronchiolitis)
diagnostic aid: pancreas
anti-neoplastic (pancreatic)
pancreatic cell manipulator
human pancreatic elastase inhibitor
pancreatic insulin secretion inhibitor
pancreatic lipase inhibitor
human pancreatic trypsin inhibitor
anti-neoplastic (active over nci cell panel)
pank-1b inhibitor (pantothenate kinase)
pank-3 activator (pantothenate kinase)
pank-3 inhibitor (pantothenate kinase)
pank-3 inhibitor (pantothenate kinase)
pank-3 activator (pantothenate kinase)
pank-1b inhibitor (pantothenate kinase)
pantothenate synthase inhibitor
anti-hpv (human papilloma virus)
par-1 antagonist (protease-activated receptor)
par-2 agonist (protease-activated receptor)
par-2 agonist (proteinase activated receptor)
par-2 antagonist (protease-activated receptor)
anti-viral measles (paramyxovirus)
anti-fungal (candida parapsilosis)
anti-parasitic
anti-fungal (anti-parasitic, fish)
anti-parasitic (topical)
parasiticide
parasiticide (veterinary)
parasympathomimetic
pth-1 antagonist (parathyroid hormone)
parg inhibitor (poly-adp-ribose glycohydrolase)
anti-parkinsonian
parkinsonism inducer (as mpp+)
poly adp-ribose polymerase-1 inhibitor (parp-1, ec 2.4.2.30)
poly adp-ribose polymerase-2 inhibitor (parp-2)
poly adp ribose polymerase-3 inhibitor (parp-3)
svps inhibitor (subviral particle secretion, hepatitis-b)
anti-protozoal (cryptosporidium parvum/ hominis)
polyamine transport inhibitor (pat)
treatment of eskape pathogens
pbp2a inhibitor (penicillin-binding protein)
bz3 benzodiazepine agonist peripheral (pbr)
bz2 benzodiazepine antagonist peripheral (pbr)
pc (pharmacological chaperone)
bacterial apoptosis promoter (pcd)
pcft inhibitor (proton-coupled folate transporter)
phencyclidine antagonist (pcp)
phencyclidine binding (pcp)
pde-b1/2 inhibitor (phosphodiesterase)
pde-delta inhibitor (phosphodiesterase)
pde inhibitor (phosphodiesterase, ec 3.1.4)
pde10a inhibitor (phosphodiesterase)
pde11 inhibitor (phosphodiesterase)
pde2 inhibitor (phosphodiesterase)
pde3 inhibitor (phosphodiesterase)
pde4a inhibitor (phosphodiesterase)
pde4b inhibitor (phosphodiesterase)
pde4c inhibitor (phosphodiesterase)
pde4d inhibitor (phosphodiesterase)
pde5 inhibitor (phosphodiesterase)
pde6 inhibitor (phosphodiesterase)
pde7 inhibitor (phosphodiesterase)
pde9 inhibitor (phosphodiesterase)
platelet-derived growth factor inhibitor (pdgf)
pyruvate dehydrogenase kinase inhibitor (pdhk)
pe treatment (premature ejaculation)
pediculicide (lice)
anti-fungal (fonsecaea pedrosoi)
blood-brain penetrant activated
blood-brain non-penetrant (relatively bbb-)
blood-brain penetrant (relatively bbb+)
inhibits excretion of penicillin
penicillin adjuvant
pbp2a inhibitor (penicillin-binding protein)
penicillin & cephalosporin precursor
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
pep/pop inhibitor (prolylendopeptidase/prolyl oligopeptidase)
phosphoenolpyruvate carboxykinase inhibitor (pepck)
nvp-3cl inhibitor (neurovirus peptidase)
dpp2 inhibitor (dipeptidyl peptidase-2)
tripeptidyl peptidase 2 inhibitor
dipeptidyl peptidase 3 inhibitor
dpp4 inhibitor (dipeptidyl peptidase 4, ec 3.4.14.5)
dpp-8 inhibitor (dipeptidyl peptidase-8)
ddp-9 inhibitor (dipeptidyl peptidase-9)
spase-1 inhibitor (signal peptidase bacterial)
peptidase inhibitor
n-acetyl-aspartyl-glutamate peptidase inhibitor (naag)
cgrp antagonist (calcitonin gene-related peptide)
glp-1 agonist (glucagon-like peptide)
renin inhibitor (non-peptide)
peptide deformylase inhibitor
beta-amyloid peptide polymerization/aggregation inhibitor
peptidoleukotriene antagonist
peptidyl prolyl isomerase inhibitor (fkbp)
peptidyl transferase inhibitor
cpp inhibitor (cytolytic protein performin)
perfume fixative
perfume or fragrance ingredient/intermediate
treatment for myocardial infarction or perfusion injury
circadian period decrease
circadian period increase
vasodilator (peripheral)
dopaminergic (peripheral)
anti-occlusion peripheral arteries
peripheral neuropathy treatment
bz3 benzodiazepine agonist peripheral (pbr)
bz2 benzodiazepine antagonist peripheral (pbr)
anti-neoplastic (ptcl, peripheral t-cell lymphoma)
anti-peristaltic
anti-neoplastic, peritoneal
perk inhibitor (endoplasmic reticulum kinase)
mptp inhibitor (mitochondrial permeability transition pore)
lipid peroxidation inhibitor
hydrogen peroxide probe
ppar-g activator (peroxisome proliferator)
ppar-d activator (peroxisome proliferator)
ppar-b activator (peroxisome proliferator)
ppar-g partial agonist (peroxisome proliferator)
ppar-a antagonist (peroxisome proliferator)
ppar-g antagonist (peroxisome proliferator)
ppar b/d inverse agonist (peroxisome proliferator)
ppar b/d partial agonist (peroxisome proliferator)
ppar-a activator (peroxisome proliferator)
ocpd treatment (obsessive compulsive personality)
anti-perspirant (anti-hidrotic)
diaphoretic (perspiration)
anti-bacterial (yersinia pestis)
pet imaging (positron emission tomography)
cardiac pet imaging (positron emission tomography)
dhodh-pf inhibitor (dihydroorotate dehydrogenase-falciparum)
pfa-m1 inhibitor (malarial metalloaminopeptidase)
pfbkfb3 inhibitor (metabolic kinase)
pfkasiii inhibitor (fatty acid synthase)
pfldh inhibitor (p.falciparum lactate dehydrogenase)
prostaglandin dp antagonist (pgd2)
15-pgdh inhibitor (15-hydroxyprostaglandin dehydrogenase)
6-pgdh inhibitor (6-phosphogluconate dehydrogenase)
pgf2a allosteric modulator (prostaglandin-f2a)
pgk phosphoglycerate kinase inhibitor (ec 2.7.2.3)
pgp overexpression inhibitor (plasma membrane glycoprotein)
ph indicator, non-invasive
phagocytosis stimulant
chimp-human pharmacokinetics compared
pc (pharmacological chaperone)
cell arrest at g2/m phase
phd2 inhibitor (prolyl hydroxylase-2)
phencyclidine antagonist (pcp)
phencyclidine binding (pcp)
phenylethanolamine methyl-transferase inhibitor (pnmt, ec 2.1.1.28)
lamprey pheromone
insect pheromone
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
mkp-1 inhibitor (mitogen activated protein kinase phosphatase)
cdc25a inhibitor (phosphatase)
mptp-b inhibitor (microbacterium tyrosine phosphatase)
yoph inhibitor (yersinia outer protein phosphatase)
ptp-1b inhibitor (protein tyrosine phosphatase)
protein phosphatase 1 inhibition (pp1)
protein phosphatase 2a inhibition (pp2a)
alkaline phosphatase inducer
hepatic glucose-6-phosphatase inhibitor
cdc-25b cell division cycle phosphatase inhibitor
alkaline phosphatase inhibitor (ec 3.1.3.1)
ptpn-22 inhibitor (lymphoid tyrosine phosphatase, lyp)
pme-1 inhibitor (protein phosphatase methylesterase)
ptp-shp2 inhibitor (protein tyrosine phosphatase-src)
sphingosine-1-phosphate-5 agonist (s1p-5, aequorin)
sphingosine-1-phosphate agonist-1 (s1p-1, b-arrestin)
sphingosine-1-phosphate antagonist (s1p)
g6pd inhibitor (glucose-6-phosphate dehydrogenase)
cysk1 inhibitor (pyridoxal phosphate-dependent-o-acetyl sulfhydrylase)
gadph binder (glyceraldehyde-3-phosphate, g3dph)
hlda inhibitor (glycero-manno-heptose-7-phosphate kinase)
hlde inhibitor (glycero-manno-heptose-7-phosphate kinase)
sphingosine-1-phosphate modulator
dxr inhibitor (deoxyxylulose-phosphate reductoisomerase, ispc)
glucosamine-6-phosphate synthase inhibitor
enolpyruvateshikamate-3-phosphate synthase inhibitor (epsps)
pts inhibitor (phosphatidylcholine synthase)
pi4kiiia inhibitor (phosphatidylinositol kinase)
phospho-stat3 inhibitor
pde4a inhibitor (phosphodiesterase)
pde6 inhibitor (phosphodiesterase)
pde11 inhibitor (phosphodiesterase)
pde7 inhibitor (phosphodiesterase)
pde10a inhibitor (phosphodiesterase)
pde2 inhibitor (phosphodiesterase)
pde9 inhibitor (phosphodiesterase)
pde4d inhibitor (phosphodiesterase)
tdp1 inhibitor (tyrosyl-dna phosphodiesterase)
pde-b1/2 inhibitor (phosphodiesterase)
pde4b inhibitor (phosphodiesterase)
pde4c inhibitor (phosphodiesterase)
pde-delta inhibitor (phosphodiesterase)
pde5 inhibitor (phosphodiesterase)
pde3 inhibitor (phosphodiesterase)
npp-1 inhibitor (nucleotide pyrophosphate/phosphodiesterase-1)
tdp2 inhibitor (tyrosyl-dna-phosphodiesterase-2)
pde inhibitor (phosphodiesterase, ec 3.1.4)
cgmp phosphodiesterase inhibitor
cyclic amp phosphodiesterase inhibitor (camp)
phosphoenolpyruvate carboxykinase inhibitor (pepck)
6-pgdh inhibitor (6-phosphogluconate dehydrogenase)
pgk phosphoglycerate kinase inhibitor (ec 2.7.2.3)
pi-3ka inhibitor (phosphoinositide kinase alpha)
pi-3kb inhibitor (phosphoinositide kinase beta)
pi-3kd inhibitor (phosphoinositide kinase delta)
pi-3kg inhibitor (phosphoinositide kinase gamma)
pi-3kc inhibitor (phosphoinositide kinase) (vps-34)
pld-1 inhibitor (phospholipase-1)
pld2 inhibitor (phospholipase-2)
phospholipase a2 inhibitor (ec 3.1.1.4)
phospholipase c inhibitor
pld inducer (phospholipidosis)
ppt inhibitor (phosphopantetheinyl transferase)
atp-prt inhibitor (atp phosphoribosyl transferase)
pyrimidine phosphoribosyl transferase inhibitor
nampt inhibitor (nicotinamide phosphororibosyltransferase)
phosphorus source (veterinary)
uridine phosphorylase inhibitor
thymidine phosphorylase inhibitor
glycogen phosphorylase inhibitor (ec 2.4.1.1)
purine nucleoside phosphorylase inhibitor (pnp, ec 2.4.2.1)
tau phosphorylation inhibitor
oxidative phosphorylation uncoupler
photo-unstable
photoactivatable probe
photoaffinity label
photoaffinity probe
dna photocleaver
photoluminescence reduction
spect imaging (single photon emission computed tomography)
photosensitizer
photoswitchable
cytochrome p680 photosynthesis inhibitor (hill reaction)
photosystem-2 inhibitor
phytoalexin
phytoene desaturase inhibitor
pi-3ka inhibitor (phosphoinositide kinase alpha)
pi-3kb inhibitor (phosphoinositide kinase beta)
pi-3kc inhibitor (phosphoinositide kinase) (vps-34)
pi-3kd inhibitor (phosphoinositide kinase delta)
pi-3kg inhibitor (phosphoinositide kinase gamma)
pi4kiiia inhibitor (phosphatidylinositol kinase)
bleaching agent (pigment synthesis inhibitor)
pigmentation agent
xeroderma pigmentosum-g (xpg)
pilus chaperone blocker (pilicide)
pilus chaperone blocker (pilicide)
pim-1 kinase inhibitor (proto-oncogene)
pim-2 kinase inhibitor
pim-3 kinase inhibitor
pineal hormone
piscicide (fish)
anterior pituitary activator
anterior pituitary activator (swine)
diagnostic aid: pituitary function
pituitary inhibitor (hypophysis)
anterior pituitary suppressant
pk activator (pyruvate kinase)
dna-pk inhibitor (dna-dependent protein kinase)
pk inhibitor (pyruvate kinase)
protein kinase a inhibitor (pka)
pkc-e inhibitor (protein kinase-c-epsilon)
pkc-theta inhibitor (protein kinase-c)
pkcz inhibitor (protein kinase-c zeta)
pkk-4 inhibitor (polo-like kinase)
anti-neoplastic (placlitaxel/mdr resistant)
plant extract
plant fertility regulator
alkaloid-like (plant/fungal)
plant growth inhibitor
plant growth regulator
plant growth stimulant
anti-plaque
anti-bacterial (dental plaque)
half-life in animal/plasma
plasma kallikrein inhibitor
pgp overexpression inhibitor (plasma membrane glycoprotein)
plasmepsin-1 inhibitor (malarial)
plasmepsin ii inhibitor (malarial)
plasmin inhibitor
upa inhibitor (urokinase plasminogen activator)
plasminogen activator inhibitor
tissue plasminogen activator (tpa)
urokinase plasminogen activator (upa)
anti-neoplastic (plasmocytoma)
anti-plasmodial (berghei)
anti-plasmodial (chabaudi)
anti-plasmodial (falciparum)
anti-plasmodial (falciparum chloroquine resistant)
anti-plasmodial (plasmodium cynomolgi)
anti-plasmodial (veterinary)
anti-plasmodial (yoelii)
anti-plasmodial (plasmodium cynomolgi)
anti-plasmodium (vivax)
platelet activator
thrombogenic (platelet aggregant)
p2y1 platelet antagonist
platelet anti-aggregant (paf)
platelet-derived growth factor inhibitor (pdgf)
larvicide (hylemya platura, seed corn borer)
pld-1 inhibitor (phospholipase-1)
pld inducer (phospholipidosis)
pld2 inhibitor (phospholipase-2)
treatment pleural effusion
anti-neoplastic (pleural mesothelioma)
plk-1 inhibitor (polo-like kinase)
psc inducer (pluripotent stem cell)
pme-1 inhibitor (protein phosphatase methylesterase)
anti-pneumocystic carinii
anti-bacterial (klebsiella pneumoniae gram-)
anti-bacterial (streptococcus pneumoniae gram+)
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
phenylethanolamine methyl-transferase inhibitor (pnmt, ec 2.1.1.28)
purine nucleoside phosphorylase inhibitor (pnp, ec 2.4.2.1)
poison
castor bean poison
poison (hemlock)
poison (hemlock water dropwort)
poison rhododendron
poison (toad/frog)
antidote glycol methanol poisoning
cyanide poisoning antidote
arsine poisoning antidote
anti-viral (polio t1 maheney)
plk-1 inhibitor (polo-like kinase)
pkk-4 inhibitor (polo-like kinase)
parg inhibitor (poly-adp-ribose glycohydrolase)
poly adp-ribose polymerase-1 inhibitor (parp-1, ec 2.4.2.30)
poly adp-ribose polymerase-2 inhibitor (parp-2)
poly adp ribose polymerase-3 inhibitor (parp-3)
poly d(a-t) dna binder
poly d(c-g) dna binder
poly-q anti-aggregant (anti-huntington's)
polyamine transport inhibitor (pat)
polycystic kidney disease treatment
hbvp inhibitor (hepatitis-b viral polymerase)
rdp2 inhibitor (rna polymerase)
poly adp-ribose polymerase-1 inhibitor (parp-1, ec 2.4.2.30)
poly adp-ribose polymerase-2 inhibitor (parp-2)
poly adp ribose polymerase-3 inhibitor (parp-3)
dna directed rna polymerase inhibitor
dna polymerase inhibitor
hepatitis c polymerase inhibitor (hcv)
hcv-ns5b rna polymerase inhibitor (hepatitis c)
tau fibrilization inhibitor (polymerization, aggregation)
beta-amyloid peptide polymerization/aggregation inhibitor
tubulin polymerization inhibitor
oatp1-b1 inhibitor (organic anion transporting polypeptide)
oatp1-b3 inhibitor (organic anion transporting polypeptide)
oatp2-b1 inhibitor (organic anion transporting polypeptide)
anti-diuretic (polyuria)
pompe disease treatment
pep/pop inhibitor (prolylendopeptidase/prolyl oligopeptidase)
wnt inhibition (porcn)
k2p potassium channel modulator (twin pore)
mptp inhibitor (mitochondrial permeability transition pore)
carcinogenicity tested not positive
pam (positive allosteric modifier)
positive chronotropic (increase heart rate)
positive inotrope (strengthen muscle contraction)
pet imaging (positron emission tomography)
cardiac pet imaging (positron emission tomography)
contraceptive (post-coital)
herbicide (post-emergence)
potassium atp channel opener (sarcolemmal)
potassium channel blocker
ikca calcium activated potassium channel blocker
potassium channel k-7 modulator/inhibitor (kcnq-2)
kir potassium channel modulator (inwardly rectifying)
k2p potassium channel modulator (twin pore)
ik/sk potassium channel modulators
potassium channel opener
kca1.1 potassium channel opener (ca and voltage gated)
p-cab (potassium-competitive acid blocker)
ikur inhibitor (potassium ion current, atrium)
diuretic (potassium-sparing)
larvicide (colorado potato beetle)
insecticide (potential)
trpa1 agonist (transient receptor potential ankyrin)
trpa1 antagonist (transient receptor potential ankyrin)
trpm8 antagonist (transient receptor potential melastatin)
anti-biotic potentiator
liposome potentiator
catacholamine potentiator
anti-neoplastic (potentiator)
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
anti-viral (poultry)
anti-fungal (powdery mildew)
anti-viral (vzv, pox)
rdrp inhibitor (rna-dependent,rna-poylmerase, ec 2.7.7.48)
protein phosphatase 1 inhibition (pp1)
protein phosphatase 2a inhibition (pp2a)
ppar-a activator (peroxisome proliferator)
ppar-a antagonist (peroxisome proliferator)
ppar-b activator (peroxisome proliferator)
ppar b/d inverse agonist (peroxisome proliferator)
ppar b/d partial agonist (peroxisome proliferator)
ppar-d activator (peroxisome proliferator)
ppar-g activator (peroxisome proliferator)
ppar-g antagonist (peroxisome proliferator)
ppar-g partial agonist (peroxisome proliferator)
proton pump inhibitor (ppi)
ppt inhibitor (phosphopantetheinyl transferase)
prcp inhibitor (prolylcarboxypeptidase, ec 3.4.16.2)
sedative (pre-anesthetic)
herbicide (pre-emergence)
treatment precocious puberty
treatment of precocious puberty
drug precursor
prostaglandin precursor
penicillin & cephalosporin precursor
coenzyme precursor
aromatic amino acids (precursor)
pregnane-x agonist (px)
pregnane-x antagonist (px)
pe treatment (premature ejaculation)
prep inhibitor (prolyl oligopeptidase, ec 3.4.21.26)
preservative
wood preservative
dopamine agonist (cns presynaptic)
cancer preventative
immunosuppressant (prevents implant rejection)
dna primase inhibitor
anti-prion (tse, cjd, scrapie, misfolded protein)
prmt-1 inhibitor (protein arginine methyl-transferase)
prmt-3 inhibitor (protein methyltransferase)
apc inhibitor (pro-coagulant)
hyperglycemic (pro-diabetic)
pro-vitamin d
procollagenase-c proteinase inhibitor
prodrug
anti-arthritic prodrug
hypoxia activated prodrug
adept (antibody directed prodrug therapy)
gdept (gene directed prodrug therapy)
eph-b3 inhibitor (erythropoietin-producing hepatocarcinoma receptor)
beta-amyloid production inhibitor
a2e production inhibitor
rage inhibitor (receptor advanced glycation end products)
age inhibitor (advanced glycation end products)
stem/progenitor cell inhibitor
progeria treatment
progesterone antagonist
progesterone modulator (sprm)
progestin (progestogen agonist)
progestin (veterinary)
progestin (progestogen agonist)
progestogen (oral)
fop (fibrodysplasia ossificans progressiva)
prohibited (regulated) drug
laxative (cathartic, prokinetic)
anti-prolactin
prolactin inhibitor
t-cell proliferation inhibitor
anti-proliferative
mesangial cell proliferaton inhibitor (mcp)
ppar-g activator (peroxisome proliferator)
ppar-d activator (peroxisome proliferator)
ppar-b activator (peroxisome proliferator)
ppar-g partial agonist (peroxisome proliferator)
ppar-a antagonist (peroxisome proliferator)
ppar-g antagonist (peroxisome proliferator)
ppar b/d inverse agonist (peroxisome proliferator)
ppar b/d partial agonist (peroxisome proliferator)
ppar-a activator (peroxisome proliferator)
prolificate for agc kinases
pyk2 inhibitor (proline-rich tyrosine kinase)
phd2 inhibitor (prolyl hydroxylase-2)
peptidyl prolyl isomerase inhibitor (fkbp)
pep/pop inhibitor (prolylendopeptidase/prolyl oligopeptidase)
prep inhibitor (prolyl oligopeptidase, ec 3.4.21.26)
prcp inhibitor (prolylcarboxypeptidase, ec 3.4.16.2)
pep/pop inhibitor (prolylendopeptidase/prolyl oligopeptidase)
tumorogenic or tumor promoter
drought tolerance promoter
animal growth promoter
hematinic (hemaglobin promoter)
sleep promoter (anti-insomnia)
bacterial apoptosis promoter (pcd)
stomachic (promotes function)
apl treatment (acute promyelocytic leukemia)
nerve gas prophylactic
malaria prophylactic
dental caries (prophylactic)
prostaglandin
prostaglandin d1 antagonist
prostaglandin d2 agonist
prostaglandin d2 antagonist
prostaglandin d2 synthase inhibitor
prostaglandin dp antagonist (pgd2)
prostaglandin e1 agonist
prostaglandin e1 antagonist
prostaglandin e2 agonist
prostaglandin e2 antagonist
mpges-1 inhibitor (microsomal prostaglandin e2 synthase)
prostaglandin e3 agonist
prostaglandin e3 antagonist
prostaglandin e4 agonist
prostaglandin e4 antagonist
pgf2a allosteric modulator (prostaglandin-f2a)
prostaglandin f2a agonist
prostaglandin f2a antagonist
prostaglandin h2 antagonist
prostaglandin i2 agonist
prostaglandin i2 antagonist
prostaglandin precursor
prostaglandin synthetase inhibitor
anti-neoplastic (prostate)
crpc treatment (castration resistant prostate cancer)
prostate growth inhibitor
prostate specific membrane antigen inhibitor (psma)
bph treatment (benign prostatic hyperplasia)
anti-prostatic hypertrophy
pzu antagonist (protamine zinc uracil)
maspin inducer (mammary serine protease)
usp1/uaf1 inhibitor (ubiquitin-specific protease)
uch-l1 inhibitor (ubiquitin-specific protease)
par-1 antagonist (protease-activated receptor)
par-2 antagonist (protease-activated receptor)
par-2 agonist (protease-activated receptor)
hiv protease dimerization inhibitor
thiol protease inhibitor
chymotrypsin protease inhibitor
cysteine protease inhibitor
dengue 2 ns2b protease inhibitor
protease inhibitor
hiv protease inhibitor
aspartyl protease inhibitor (bace-2)
hepatitis c protease inhibitor (hcv)
hcv-ns3 protease inhibitor (hepatitis c)
proteasome inhibitor
anti-prion (tse, cjd, scrapie, misfolded protein)
hsp-90 inhibitor (heat shock protein)
bcl-2 inhibitor (anti-apoptotic protein)
sfrp-1 inhibitor (secreted frizzled-related protein)
tspo binder (translocator protein)
hsp-70 inhibitor (heat shock protein)
xiap antagonist (x-linked inhibitor apoptosis protein)
fap inhibitor (fibroblast activator protein)
vap-1 inhibitor (vascular adhesion protein)
mbt antagonist (methyl-lysine binding protein)
hsp-78d inhibitor (grp-78 glucose regulated protein)
srebp inhibitor (sterol regulatory element binding protein)
myd-88 inhibitor (myeloid differentiation protein)
bmp-2 stimulator (bone morphogenic protein)
bcl-xl inhibitor (anti-apoptotic protein)
p97 inhibitor (vcp, valosine containing protein)
idp inhibitor (inhibitor differentiation protein)
fto inhibitor (fatty mass & obesity assoc. protein)
hsp-27 inhibitor (heat shock protein)
gkrp modulator (glucokinase regulatory protein)
bmp-6 inhibitor (bone morphogenic protein)
pbp2a inhibitor (penicillin-binding protein)
rpa inhibitor (replication protein-a)
g-protein activator
pad inhibitor (protein arginine deaminase)
prmt-1 inhibitor (protein arginine methyl-transferase)
epac-2 antagonist (exchange protein camp activated)
gpcr-35 agonist (g-protein-coupled)
gpcr-109a modulator (g-protein-coupled)
gpba-1 agonist (g-protein-coupled bile acid)
gpcr-109a agonist (g-protein coupled, niacin-109a)
gpcr119 agonist (g-protein coupled receptor)
tgr-5 agonist (g-protein coupled receptor)
gpcr-30 agonist (g-protein coupled receptor)
gpcr119 antagonist (g-protein coupled receptor)
gpcr-120 agonist (g-protein coupled receptor)
gpcr-139 agonist (g-protein coupled receptor)
gpr-119 agonist (g-protein coupled receptor)
gpcr-52 (g-protein coupled receptor)
gpcr-40 agonist (g-protein coupled receptor, ffa-1)
gpcr-40 antagonist (g-protein coupled receptor, ffa-1)
protein-protein disruptor
cenp-e inhibitor (centromere-assoc. protein-e)(kinase-7)
chaperone of protein folding
anti-apoptosis protein inhibitor (aap)
cholesterolester transfer protein inhibitor (cetp)
kinesin spindle protein inhibitor (ksp)
eif4e/eif4g protein interaction inhibitor
dna-pk inhibitor (dna-dependent protein kinase)
cdpk-1 inhibitor (calcium-dependent protein kinase)
apkc modulator (atypical protein kinase)
map4k2 inhibitor (mitogen-activated protein kinase)
protein kinase a inhibitor (pka)
protein kinase b inhibitor (akt)
protein kinase b inhibitor (akt-1)
protein kinase b inhibitor (akt-2)
protein kinase b inhibitor (akt-3)
pkc-theta inhibitor (protein kinase-c)
protein kinase c activator
pkc-e inhibitor (protein kinase-c-epsilon)
protein kinase c inhibitor
pkcz inhibitor (protein kinase-c zeta)
protein kinase-c1 modulator
protein kinase ck2 inhibitor
protein kinase d inhibitor
protein kinase g inhibitor
abl protein kinase inhibitor (bcr-abl)
mitogen-activated protein kinase inhibitor (p38-map)
protein kinase inhibitor (rsk2)
mkp-1 inhibitor (mitogen activated protein kinase phosphatase)
prmt-3 inhibitor (protein methyltransferase)
covalent protein modifier (irreversible)
microsomal triglyceride transfer protein (mtp) inhibitor
cpp inhibitor (cytolytic protein performin)
yoph inhibitor (yersinia outer protein phosphatase)
protein phosphatase 1 inhibition (pp1)
protein phosphatase 2a inhibition (pp2a)
pme-1 inhibitor (protein phosphatase methylesterase)
protein-protein disruptor
gpr-103 antagonist (g-protein receptor)
rgs4 inhibitor (regulator g-protein signaling)
nps inhibitor (notch protein signaling)
acps inhibitor (acyl carrier protein synthase)
protein synthesis inhibitor
bacterial protein synthesis inhibitor (23s-ribosome)
lck sh2 inhibitor (lymphocyte-specific protein tyrosine kinase)
protein tyrosine kinase inhibitor (ptk)
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
ptp-1b inhibitor (protein tyrosine phosphatase)
ptp-shp2 inhibitor (protein tyrosine phosphatase-src)
ftsz inhibition (filimentation temp.-sensitive protein z)
par-2 agonist (proteinase activated receptor)
procollagenase-c proteinase inhibitor
prothrombinogenic
prothyrotropin
pim-1 kinase inhibitor (proto-oncogene)
pcft inhibitor (proton-coupled folate transporter)
proton pump inhibitor (ppi)
protoporphyrinogen oxidase inhibitor
anti-protozoal
anti-protozoal (babesia)
anti-protozoal (coccidia)
anti-protozoal (cryptosporidium parvum/ hominis)
anti-protozoal (giardia)
anti-protozoal (histomonas)
anti-protozoal (leishmaniasis)
anti-protozoal (toxoplasma gondii)
anti-protozoal (trichomonas)
anti-protozoal (trypanosoma)
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
anti-protozoal (veterinary)
protozoan super toxicant (tetrahymena spp.)
prrb-prra two-component histidine kinase
prrb-prra two-component histidine kinase
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
atp-prt inhibitor (atp phosphoribosyl transferase)
anti-pruritic (keratolytic)
anti-pruritic (topical)
ps inhibitor (pyrimidine synthesis)
psc inducer (pluripotent stem cell)
psd-95/nmda inhibitor
anti-bacterial (pseudomonas)
anti-bacterial (pseudomonas aeruginosa gram-)
prostate specific membrane antigen inhibitor (psma)
anti-psoriatic (keratolytic)
psychodysleptic (hallucinogenic)
psychostimulant
anti-psychotic (neuroleptic)
psychotomimetic
psychotropic (mental modifier)
anti-neoplastic (ptcl, peripheral t-cell lymphoma)
pten-deficient cancer treatment
ptr-1 inhibitor (pteridine reductase)
pteroic acid synthase inhibitor
pth-1 antagonist (parathyroid hormone)
protein tyrosine kinase inhibitor (ptk)
ptp-1b inhibitor (protein tyrosine phosphatase)
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
ptp-shp2 inhibitor (protein tyrosine phosphatase-src)
ptpn-22 inhibitor (lymphoid tyrosine phosphatase, lyp)
ptr-1 inhibitor (pteridine reductase)
pts inhibitor (phosphatidylcholine synthase)
treatment precocious puberty
treatment of precocious puberty
hypertensive (pulmonary)
anti-copd (chronic obstructive pulmonary disease)
ipf treatment (ideopathic pulmonary fibrosis)
anti-hypertensive (pulmonary, pah)
pulmonary surfactant
bradycardic (reduce pulse rate)
efflux pump inhibitor
proton pump inhibitor (ppi)
miotic (pupil contraction)
mydriatic (dilates pupils)
p2y-11 receptor agonist (purine metabromic)
p2x4 antagonist (purine nucleoside)
purine nucleoside phosphorylase inhibitor (pnp, ec 2.4.2.1)
p2y12 antagonist (purine, nucleotide)
p2y-2 agonist (purine, nucleotide)
p2y-4 agonist (purine, nucleotide)
p2y-6 agonist (purine, nucleotide)
p2y1 agonist (purine, nucleotide)
purine synthesis inhibitor
p2x2 antagonist (purinergic)
purinergic a2a antagonist
purinergic antagonist (p2x3)
purinergic p2 antagonist
purinergic p2x7 antagonist
pregnane-x agonist (px)
pregnane-x antagonist (px)
pyk2 inhibitor (proline-rich tyrosine kinase)
anti-bacterial (helicobacter pylori gram-)
anti-bacterial (streptococcus pyogenes gram+)
anti-pyretic hypothermic (anti-febric)
anti-fungal (pyricularia oryzae)
cysk1 inhibitor (pyridoxal phosphate-dependent-o-acetyl sulfhydrylase)
pyrimidine phosphoribosyl transferase inhibitor
ps inhibitor (pyrimidine synthesis)
pyrogen
npp-1 inhibitor (nucleotide pyrophosphate/phosphodiesterase-1)
pyruvate dehydrogenase kinase inhibitor (pdhk)
4-hppd inhibitor (hydroxyphenyl pyruvate dioxygenase)
pk inhibitor (pyruvate kinase)
pk activator (pyruvate kinase)
pzu antagonist (protamine zinc uracil)
qfr inhibitor (quinol/fumarate reductase)
mitochondrial electron transport complex iii (qi) inhibitor
qr-2 inhibitor (quinone reductase)
herg channel blocker (increase qt interval, cardiac risk)
herg channel optimized (qt interval decreased)
qfr inhibitor (quinol/fumarate reductase)
nqo2 inhibitor (nad quinone oxidoreductase, ec 1.10.99.2)
nqo1 inhibitor (nad quinone oxidoreductase, ec 1.6.99.2)
qr-2 inhibitor (quinone reductase)
anti-bacterial (quorum sensing inhibitor)
r67 dhfr inhibitor (dihydrofolate reductase)
raas inhibitor (renin-angiotensin-aldosterone system)
rabggtase inhibitor
rac-1 inhibitor (rho-gtp-ase)
glutamate racemase (muri)
rad-51 inhibitor
atr inhibitor (ataxia rad-related)
atr inhibitor (ataxia telangiectasia rad3 related)
free radical generator
free radical scavenger
radioactive agent
radiodiagnostic/ligand
radiopaque contrast agent
radioprotector
radiosensitizer
c-raf kinase inhibitor
b-raf kinase inhibitor (braf)
rage inhibitor (receptor advanced glycation end products)
mtor inhibitor (mammalian target of rapamycin)
mtor c1/c2 inhibitor (mamalian target of rapamycin)
retinoic acid receptor agonist (rar)
rar-b2 ligand (retinoic acid receptor b2)
ras inhibitor (signaling)
dihydrofolate reductase inhibitor (dhfr, rat liver)
carcinogen (rat, mouse)
cox-2/cox-1 inhibition ratio
rdp2 inhibitor (rna polymerase)
recombinant-dependent replication inhibition (rdr)
rdrp inhibitor (rna-dependent,rna-poylmerase, ec 2.7.7.48)
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
sigma receptors inhibitor
recombinant-dependent replication inhibition (rdr)
b-arrestin signaling recruiter
kir potassium channel modulator (inwardly rectifying)
insecticide (red mites)
rubefacient (skin reddener)
bradycardic (reduce pulse rate)
anoikis (tumor adhesion reducer)
chcr-1 inhibitor (chinese hamster carbonyl reductase)
mur-b inhibitor (udp-ep-glu-nac reductase)
try-r inhibitor (trypanothione reductase)
fab-g inhibitor (b-ketoacyl-acp-reductase)
fab-i inhibitor (enoyl-acp-reductase)
qr-2 inhibitor (quinone reductase)
akr1c3 inhibitor (aldo-keto reductase)
r67 dhfr inhibitor (dihydrofolate reductase)
ptr-1 inhibitor (pteridine reductase)
qfr inhibitor (quinol/fumarate reductase)
aldh-3 inhibitor (aldose reductase)
5-alpha reductase-2 inhibitor
aldh-1 inhibitor (aldose reductase, ec 1.1.1.21)
7dhcr inhibitor (7-dehydrocholesterol reductase, ec 1.3.1.21)
ribonucleotide reductase inhibitor
enoyl-acp reductase inhibitor
dihydrofolate reductase inhibitor (dhfr, bacillus anthracis)
dihydrofolate reductase inhibitor (dhfr, candida)
dihydrofolate reductase inhibitor (dhfr, ec 1.5.1.3)
dihydrofolate reductase inhibitor (dhfr, rat liver)
dihydrofolate reductase inhibitor (dhrf, chicken liver)
hmg-coa reductase inhibitor (hmgr, ec 1.1.1.34)
5-alpha reductase inhibitor (testosterone)
thioredoxin reductase inhibitor (trxr, ec 1.8.1.9)
photoluminescence reduction
dxr inhibitor (deoxyxylulose-phosphate reductoisomerase, ispc)
anti-gerd (gastroesophagael reflux)
anti-gerd (gastroesophageal reflux disease)
cholesterol ester reformation inhibitor
anti-neoplastic (taxane refractory)
refrigerant
irap inhibitor (insulin-regulated aminopeptidase)
prohibited (regulated) drug
erk-1/erk-2 inhibitor (extracellular signal-regulated kinase)
sgk-1 inhibitor (serum glucocorticoid-regulated kinase)
erk-5 inhibitor (extracellular signal-regulated kinase, mapk-7)
hsp-78d inhibitor (grp-78 glucose regulated protein)
growth regulator
bone calcium regulator
plant growth regulator
insect growth regulator
plant fertility regulator
mood regulator
hepato-biliary regulator
cftr blocker (cystic fibrosis transmembrane conductuctance regulator)
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
agr inhibitor (accessory gene regulator)
serd (estrogen receptor down-regulator)
rgs4 inhibitor (regulator g-protein signaling)
turf growth regulator (grass)
srebp inhibitor (sterol regulatory element binding protein)
gkrp modulator (glucokinase regulatory protein)
treatment renal transplant rejection
immunosuppressant (prevents implant rejection)
uterine relaxant
skeletal muscle relaxant
muscle relaxant
smooth muscle relaxant
cervical relaxant
muscle relaxant (short duration)
muscle relaxant (veterinary)
rxfp-1 agonist (relaxin)
vasodilator (renal)
renal dihydropeptidase inhibitor
renal failure treatment
diagnostic aid: renal function
anti-neoplastic (renal / kidney)
treatment renal transplant rejection
raas inhibitor (renin-angiotensin-aldosterone system)
renin inhibitor
renin inhibitor (non-peptide)
renin inhibitor (oral)
gene repair of nonsense mutation damage
repartitioning agent
bir2 selective (second baculovirus iap repeat)
lrrk2 inhibitor (leucine-rich repeat kinase)
insect repellant
cockroach repellant
bird repellant
arthropod repellant
ishemia/reperfusion treatment
estrogenic hrt (hormone replacement therapy)
electrolyte replenisher adjuvant
anti-bacterial (tuberculosis,dormant,non-replicating)
recombinant-dependent replication inhibition (rdr)
sl3-rna hiv replication inhibitor
rpa inhibitor (replication protein-a)
reproductive toxicity (ca prop. 65)
reproductive toxicity (ca prop. 65, female)
reproductive toxicity (ca prop. 65, male)
ire-1 inhibitor (inositol-requiring enzyme)
multi-drug resistance inhibitor/extruder (mdr1, mrp1)
beta-lactamase resistant
anti-bacterial (enterococcus casselflavus gram-, vancomycin resistant)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
anti-plasmodial (falciparum chloroquine resistant)
anti-neoplastic (placlitaxel/mdr resistant)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
crpc treatment (castration resistant prostate cancer)
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
bone resorption (osteoclast) inhibitor
anti-bacterial (respiratory)
anti-spasmodic (respiratory)
anti-inflammatory (respiratory)
respiratory aid
respiratory stimulant
respiratory stimulant (cardiac)
respiratory stimulant (cns)
rsv anti-viral (respiratory syncytial fusion)
restenosis inhibitor
restless leg treatment
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
ret kinase inhibitor
mineralocorticoid (na retention, k loss)
erap-1 inhibitor (endoplasmic reticulum aminopeptidase)
erap-2 inhibitor (endoplasmic reticulum aminopeptidase)
perk inhibitor (endoplasmic reticulum kinase)
retinoic acid receptor agonist (rar)
retinoic acid receptor antagonist
rar-b2 ligand (retinoic acid receptor b2)
retinoic acid receptor binder
retinoid isomerohydrolase inhibitor
alpha retinoid x agonist (rxr)
alpha retinoid x antagonist
anti-retinopathic
anti-retroviral
ndri inhibitor (norepinephrine dopamine reuptake)
dopamine reuptake inhibitor
gaba reuptake inhibitor (gamma amino butyric acid)
norepinephrine reuptake inhibitor (nri)
triple reuptake inhibitor (serotonin, norepinephrine, dopamine)
serotonin-norepinephrine reuptake inhibitor (snri)
5-ht serotonin reuptake inhibitor (ssri)
ncx reverse inhibitor (sodium/calcium)
anti-viral (hiv, reverse transcriptase)
anesthesia reverser
rgs4 inhibitor (regulator g-protein signaling)
rhabdomyosarcoma treatment
anti-rheumatic
anti-rheumatoid arthritis
allergic rhinitis treatment
anti-viral (human rhinovirus)
anti-fungal (rhizoctonia bataticola)
rac-1 inhibitor (rho-gtp-ase)
rock-1 inhibitor (rho kinase-1)
rock-2 inhibitor (rho kinase-2)
poison rhododendron
riboflavine antagonist
ribonuclease-a inhibitor
ribonuclease-h inhibitor
garft inhibitor (glycinamide ribonucleotide formyl transferase)
ribonucleotide reductase inhibitor
dpre1 inhibitor (decaprenylphosphoryl-b-d-ribose-2'-epimerase)
parg inhibitor (poly-adp-ribose glycohydrolase)
1heh inhibitor (nicotinamide ribose kinase)
poly adp-ribose polymerase-1 inhibitor (parp-1, ec 2.4.2.30)
poly adp-ribose polymerase-2 inhibitor (parp-2)
poly adp ribose polymerase-3 inhibitor (parp-3)
ribosomal amino acid
ribosomal translation inhibitor
bacterial protein synthesis inhibitor (23s-ribosome)
hcv ires inhibitor (internal ribosome entry site, hepatitis c)
arf-1 inhibitor (adp-ribosylation factor)
1hur inhibitor (ribosylation factor-1)
lux-s inhibitor (s-ribosylhomocysteinase)
artd-8 inhibitor (adp-ribotransferase)
larvicide (rice borer)
lrrk2 inhibitor (leucine-rich repeat kinase)
pyk2 inhibitor (proline-rich tyrosine kinase)
anti-rickettsial
anti-fungal (trichophyton spp., ringworm, jock-itch)
riot control
herg channel blocker (increase qt interval, cardiac risk)
u1061-a rna binder
rdrp inhibitor (rna-dependent,rna-poylmerase, ec 2.7.7.48)
tgt inhibitor (t-rna guanine transglycolase)
rna helicase inhibitor
sl3-rna hiv replication inhibitor
trmd inhibitor (t-rna-n1-g37 methyltransferase)
rdp2 inhibitor (rna polymerase)
dna directed rna polymerase inhibitor
hcv-ns5b rna polymerase inhibitor (hepatitis c)
rdrp inhibitor (rna-dependent,rna-poylmerase, ec 2.7.7.48)
leucyl t-rna synthesis inhibitor
rna synthesis inhibitor
thrs inhibitor (threonyl-t-rna synthetase)
methionyl t-rna synthetase inhibitor
rna tetraloop binder
cap-dependent m-rna translation inhibitor
rnase-h inhibitor (cleavage)
tonic (roborant, restorative)
rock-1 inhibitor (rho kinase-1)
rock-2 inhibitor (rho kinase-2)
rodenticide
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
rorgt antagonist (nuclear hormone receptor gamma)
rotavirus treatment
anti-viral (rous sarcoma)
rpa inhibitor (replication protein-a)
protein kinase inhibitor (rsk2)
rsv anti-viral (respiratory syncytial fusion)
tyrosinase inhibitor (rtk, ec 1.14.18.1)
mer-rtk inhibitor (receptor tyrosine kinase)
rubefacient (skin reddener)
anti-viral (rubella)
anti-fungal (trichophyton rubrum)
artificial rum flavoring
anti-fungal (wheat rust)
rxfp-1 agonist (relaxin)
alpha retinoid x agonist (rxr)
anti-bacterial (s. aureus, mrsa, methicillin & linezolid resistant)
sphingosine-1-phosphate antagonist (s1p)
sphingosine-1-phosphate agonist-1 (s1p-1, b-arrestin)
sphingosine-1-phosphate-5 agonist (s1p-5, aequorin)
anti-fungal (saccharomyces cerevisiae)
tsd/sd treatment (tay-sachs, sandhoff diseases)
sah-mta nucleosidase inhibitor
sahr modulator (selective aromatic hydrocarbon receptor)
salivatory (sialagogue)
anti-bacterial (salmonella typhi gram-ve)
adrenocortical steroid (salt regulating)
saluretic (na+, cl- excretion)
sam-dc inhibitor (s-adenosylmethionine decarboxylase)
tsd/sd treatment (tay-sachs, sandhoff diseases)
anti-bacterial (staphylococcus saprophyticus gram+)
potassium atp channel opener (sarcolemmal)
anti-viral (rous sarcoma)
es treatment (ewing's sarcoma)
anti-neoplastic (sarcoma 180)
sarm (selective androgen modulator)
anti-viral (sars-corona)
scabicide
free radical scavenger
nitric oxide scavenger
scd-1 inhibitor (stearoyl-coa-desaturase)
anti-fungal (sporothrix schenckii)
anti-schistosomal (flukicide)
anti-schizophrenic
sclerosing agent (hardening)
als treatment (amyotrophic lateral sclerosis, lou gehrig's disease)
ms (multiple sclerosis) treatment
anti-sclerotic
anti-scorbutic
anti-prion (tse, cjd, scrapie, misfolded protein)
ultraviolet screen (sunscreen)
tsd/sd treatment (tay-sachs, sandhoff diseases)
anti-seborrheic
bir2 selective (second baculovirus iap repeat)
smac activator mimetic (second mitochondria activator caspases)
growth hormone inhibitor (secretagogue)
a-secretase enhancer
g-secretase inhibitor
k-secretase inhibitor
b-secretase inhibitor (bace-1)
g-secretase modulator
sfrp-1 inhibitor (secreted frizzled-related protein)
diagnostic aid: gastric secretion
svps inhibitor (subviral particle secretion, hepatitis-b)
ovarian e2 secretion inhibitor
pancreatic insulin secretion inhibitor
gastric anti-secretory
anxiolytic (non-sedating)
anti-histamine (non-sedating)
kappa opioid agonist (sedating)
sedative
sedative (pre-anesthetic)
sedative (veterinary)
larvicide (hylemya platura, seed corn borer)
seed germinator
seizure inducing
pan-selectin antagonist (p-selectin)
pan-selectin antagonist (p-selectin)
ssao inhibitor (semicarbazide-sensitive amino oxidase, ec 1.4.3.6)
anti-bacterial (quorum sensing inhibitor)
calcium-sensing receptor antagonist (csr, calcilytic)
ssao inhibitor (semicarbazide-sensitive amino oxidase, ec 1.4.3.6)
asic blocker (acid sensitive ion channel)
hormone sensitive lipase inhibitor (hsl)
ftsz inhibition (filimentation temp.-sensitive protein z)
insulin sensitizer
anti-septic (anti-infective)
anti-septic (intestinal)
anti-septic (oral)
anti-septic shock
anti-septic (topical)
anti-septic (urinary)
serd (estrogen receptor down-regulator)
shmt inhibitor (serine hydroxymethyltransferase
maspin inducer (mammary serine protease)
anti-estrogen (serm, selective estrogen receptor modulator)
5-ht7 serotonin agonist
5-ht1f serotonin agonist
5-ht1a serotonin agonist
5-ht2a serotonin agonist
5-ht6 serotonin agonist
5-ht3 serotonin agonist
5-ht4 serotonin agonist
5-ht2b serotonin agonist
5-ht1bd serotonin agonist
5-ht2 serotonin agonist
5-ht1b serotonin agonist
5-ht2c serotonin agonist
5-ht1d serotonin agonist
5-ht7 serotonin antagonist
5-ht1d serotonin antagonist
5-ht serotonin antagonist
5-ht2b serotonin antagonist
5-ht5a serotonin antagonist
5-ht2a serotonin antagonist
5-ht4 serotonin antagonist
5-ht6 serotonin antagonist
5-ht3 serotonin antagonist
5-ht1b serotonin antagonist
5-ht1a serotonin antagonist
5-ht2c serotonin antagonist
5-ht2 serotonin antagonist
5-ht1a serotonin binder
5-ht1b serotonin inverse agonist
5-ht3 serotonin ligand
triple reuptake inhibitor (serotonin, norepinephrine, dopamine)
serotonin-norepinephrine reuptake inhibitor (snri)
serotonin receptor binder
5-ht serotonin reuptake inhibitor (ssri)
5-ht serotonin transport inhibitor (sert)
5-ht serotonin uptake inhibitor
5-htp serotonin uptake inhibitor
5-ht serotonin transport inhibitor (sert)
sgk-1 inhibitor (serum glucocorticoid-regulated kinase)
treatment of sex-hormone disorders
fsd therapy (female sexual dysfunction)
sexual stimulant
steroidogenesis inducer (sf-1)
sfrp-1 inhibitor (secreted frizzled-related protein)
sgk-1 inhibitor (serum glucocorticoid-regulated kinase)
sodium-dependent glucose transporter-2 inhibitor (sglt2)
lck sh2 inhibitor (lymphocyte-specific protein tyrosine kinase)
shmt inhibitor (serine hydroxymethyltransferase
anti-septic shock
hsp-90 inhibitor (heat shock protein)
hsp-70 inhibitor (heat shock protein)
hsp-27 inhibitor (heat shock protein)
ptp-shp2 inhibitor (protein tyrosine phosphatase-src)
salivatory (sialagogue)
sickle cell treatment
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
iron chelator (siderophore)
siderophore synthesis inhibitor
sigma-1 agonist
sigma-1 antagonist
sigma-1 ligand
sigma-2 agonist
sigma-2 antagonist
sigma 2 ligand
sigma-3 inhibitor
sigma receptor agonist
sigma receptors inhibitor
spase-1 inhibitor (signal peptidase bacterial)
erk-1/erk-2 inhibitor (extracellular signal-regulated kinase)
erk-5 inhibitor (extracellular signal-regulated kinase, mapk-7)
stat-5 inhibitor (signal transducer activator of transcript)
stat-3 inhibitor (signal transducer activator of transcript.3)
ras inhibitor (signaling)
rgs4 inhibitor (regulator g-protein signaling)
nps inhibitor (notch protein signaling)
hedgehog signaling antagonist (hh, smo)
virulence signaling inhibitor
b-arrestin signaling recruiter
significant metabolite
anti-silicosis
hsv-1 imaging (herpes simplex)
anti-viral (hsv-1 herpes simplex)
spect imaging (single photon emission computed tomography)
sirt-1 activator (sirtuin)
sirt-1 inhibitor (sirtuin-1)
sirt-2 inhibitor (sirtuin-2)
sirt-3 inhibitor (sirtuin-3)
sirt-1 activator (sirtuin)
sirt-1 inhibitor (sirtuin-1)
sirt-2 inhibitor (sirtuin-2)
sirt-3 inhibitor (sirtuin-3)
ik/sk potassium channel modulators
skeletal muscle relaxant
anti-neoplastic (skin basal cell bcc)
rubefacient (skin reddener)
sl3-rna hiv replication inhibitor
sle treatment (systemic lupus erythematous)
sleep promoter (anti-insomnia)
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
bacterial sliding clamp inhibitor
slos treatment (smith-lemli-opitz syndrome)
smac activator mimetic (second mitochondria activator caspases)
anti-neoplastic (lung small cell)
anti-neoplastic (lung non-small cell, nsclc)
anti-viral orthopox (vaccinia/cow, smallpox)
slos treatment (smith-lemli-opitz syndrome)
smn2 gene activator/modulator
hedgehog signaling antagonist (hh, smo)
anti-addictive (nicotine, smoking cessation)
smooth muscle contractant
smooth muscle relaxant
serotonin-norepinephrine reuptake inhibitor (snri)
anti-autistic (social withdrawal)
mutant sod-1 anti-aggregant (superoxide dismutase)
sod inhibitor (superoxide dismutase, ec 1.15.1.1)
amyloidosis treatment (ttr, sodi, or p53)
hyponatremia treatment (low sodium)
ncx reverse inhibitor (sodium/calcium)
sodium channel blocker
epithelial sodium channel blocker
voltage gated sodium channel blocker (vgsc)
sodium channel modulator
sodium channel nav1.3 modulator
sodium channel nav1.4 blocker
sodium channel nav1.7 modulator
sodium channel nav1.8 modulator
sodium channel opener
asbt inhibitor (apical sodium-dependent bile acid transporter)
sodium-dependent glucose transporter-2 inhibitor (sglt2)
natriuretic (sodium excretion)
sodium-hydrogen exchange inhibitor (nhe-1)
controlled (soft) deactivation
soicr suppressor (store-overloaded-induced calcium release)
nitrification inhibitor (soil)
soil fumigant
anti-neoplastic (solid tumors)
somatostatin agonist
somatostatin antagonist (srif release-inhibiting factor)
insecticide (spodoptura eridania, southern army worm)
notch sparing
diuretic (potassium-sparing)
spase-1 inhibitor (signal peptidase bacterial)
anti-spasmodic
anti-spasmodic (gall bladder)
anti-spasmodic (gastric)
anti-spasmodic (respiratory)
anti-spasmodic (veterinary)
spasmogenic
spasmolytic
spect imaging (single photon emission computed tomography)
spermicide (spermaticide)
anti-spermatogenic
spermicide (spermaticide)
spermidine synthase inhibitor
sphingolipid synthesis inhibitor
sphingomyelinase inhibitor
sphingosine-1-phosphate-5 agonist (s1p-5, aequorin)
sphingosine-1-phosphate agonist-1 (s1p-1, b-arrestin)
sphingosine-1-phosphate antagonist (s1p)
sphingosine-1-phosphate modulator
sphk-1 inhibitor (sphingosine kinase)
sphk-2 inhibitor (sphingosine kinase)
sphk-1 inhibitor (sphingosine kinase)
sphk-2 inhibitor (sphingosine kinase)
arachnicide (spiders)
spin label imaging
anesthetic (spinal)
kinesin spindle protein inhibitor (ksp)
mps-1 inhibitor (monopolar spindle, ttk)
syk inhibitor (spleen tyrosine kinase)
spliceosome inhibitor
insecticide (spodoptura eridania, southern army worm)
marine toxin/metabolite (algal/sponge/fish)
sporicide
anti-fungal (sporothrix schenckii)
progesterone modulator (sprm)
squalene epoxidase inhibitor
squalene synthase inhibitor
anti-neoplastic (squamous)
ptp-shp2 inhibitor (protein tyrosine phosphatase-src)
c-src kinase inhibitor
c-src tyrosine kinase inhibitor
srebp inhibitor (sterol regulatory element binding protein)
somatostatin antagonist (srif release-inhibiting factor)
ssao inhibitor (semicarbazide-sensitive amino oxidase, ec 1.4.3.6)
5-ht serotonin reuptake inhibitor (ssri)
dopaminergic stabilizer
mitochondria stabilizer
microtubule stabilizer (binder, tubulin inhibitor)
anti-malarial (liver stage)
dehydrosqualene synthase inhibitor (crtm, staphylococcus aureus)
anti-bacterial (staphylococcus aureus gram+)
anti-bacterial (staphylococcus saprophyticus gram+)
stat-3 inhibitor (signal transducer activator of transcript.3)
stat-5 inhibitor (signal transducer activator of transcript)
phospho-stat3 inhibitor
scd-1 inhibitor (stearoyl-coa-desaturase)
hepatic steatosis treatment
anti-fungal (candida stellaloidea)
esc differentiation blocker (embryonic stem cell)
hsc transplant enhancer (human stem cell)
psc inducer (pluripotent stem cell)
stem cell differentiation director
blood stem cell mobilization agent
stem/progenitor cell inhibitor
mst-1 kinase inhibitor (mammalian sterile-20)
adrenocortical steroid
steroid 14-a-demethylase inhibitor
adrenocortical steroid (salt regulating)
steroid sulfatase inhibitor
adrenocortical steroid (topical)
steroid (topical)
anti-inflammatory non-steroidal (nsaid)
steroidogenesis inducer (sf-1)
sterol d8d7 isomerase binder
srebp inhibitor (sterol regulatory element binding protein)
sterol synthesis inhibitor
phagocytosis stimulant
respiratory stimulant
stimulant
cardiac stimulant
growth hormone stimulant
thymus stimulant
sexual stimulant
cns stimulant
plant growth stimulant
ovulation stimulant
cerebral circulation stimulant
glucagon stimulant
leukopoietic stimulant
gastroprokinetic (gastro-intestinal stimulant)
choleretic (cholagogue, bile stimulant)
nootropic (cerebral stimulant)
analeptic (stimulant)
respiratory stimulant (cardiac)
respiratory stimulant (cns)
appetite stimulant (orexigenic)
cns stimulant (veterinary)
appetite stimulant (veterinary)
fms inhibitor (macrophage colony-stimulating factor, csf-1, ron)
fsh agonist (follicle stimulating hormone)
fsh antagonist (follicle stimulating hormone)
gonad stimulator
bmp-2 stimulator (bone morphogenic protein)
stomachic (promotes function)
cholelitholytic agent (gall stones)
lsd treatment (lysosomal storage disease)
soicr suppressor (store-overloaded-induced calcium release)
positive inotrope (strengthen muscle contraction)
anti-bacterial (streptococcus haemolyticus gram+)
anti-bacterial (streptococcus mutans gram+)
anti-bacterial (streptococcus pneumoniae gram+)
anti-bacterial (penicillin-resistant streptococcus pneumoniae, prsp)
anti-bacterial (streptococcus pyogenes gram+)
mitogen stress response kinase inhibitor(msk-1)
ischemic stroke treatment (cardiac/cerebral)
anti-addictive (substance abuse treatment, anti-craving)
substance p inhibitor
blood substitute
anti-bacterial (bacillus subtilis gram+)
svps inhibitor (subviral particle secretion, hepatitis-b)
succinate dehydrogenase (complex ii) inhibitor (ec 1.3.5.1)
succinyl-choline synergist
steroid sulfatase inhibitor
estrone sulfatase inhibitor
cysk1 inhibitor (pyridoxal phosphate-dependent-o-acetyl sulfhydrylase)
h2s donor (hydrogen sulfide releasing)
sulfide releasing agent
sulfonylurea receptor binder
b-aryl-sulfotransferase-4 inhibitor (bast-4)
sulfotransferase inhibitor
sulfur mustard degredation product
ultraviolet screen (sunscreen)
microtox super-active
protozoan super toxicant (tetrahymena spp.)
mutant sod-1 anti-aggregant (superoxide dismutase)
sod inhibitor (superoxide dismutase, ec 1.15.1.1)
intracellular superoxide generator
keratolytic (suppreses keratinocyte hyperproliferation)
anterior pituitary suppressant
anorexic (appetite suppressant)
dermatitis suppressant (herpetiformis or atopic)
anti-mitotic (suppresses cell division)
anti-inflammatory (cytokine suppressing, csaid)
soicr suppressor (store-overloaded-induced calcium release)
hbsag inhibitor (hepatitis-b surface antigen)
surfactant
pulmonary surfactant
svps inhibitor (subviral particle secretion, hepatitis-b)
sweetener
non-nutritive sweetener
toxic sweetener
syk inhibitor (spleen tyrosine kinase)
sympatholytic
sympathomimetic (adrenergic)
estrus synchronizer
rsv anti-viral (respiratory syncytial fusion)
insecticide synergist
succinyl-choline synergist
anti-bacterial synergist (mdr)
synergist (non-specific)
acps inhibitor (acyl carrier protein synthase)
cytochrome p450 inhibitor (cyp-11b2, aldosterone synthase)
dhps inhibitor (dihydropteroate synthase)
mpges-1 inhibitor (microsomal prostaglandin e2 synthase)
pfkasiii inhibitor (fatty acid synthase)
cytochrome p450 inhibitor (cyp-11b1, corticosterone synthase)
thy-x inhibitor (fdts, flavin-dependent thymidylate synthase)
gcs inhibitor (glucosylceramide synthase)
ahas inhibitor (acetohydroxyacid synthase)
pts inhibitor (phosphatidylcholine synthase)
upps inhibitor (undecaprenyl diphosphate synthase)
fas-ii inhibitor (fatty acid synthase)
fab-b/f inhibitor (b-ketoacetyl-acp synthase 1/2)
fab-h inhibitor (b-ketoacetyl acp synthase-3)
gs inhibitor (glutamine synthase ec 6.3.1.2)
gsh synthase inducer (glutathione)
squalene synthase inhibitor
glucolipid synthase inhibitor
gmp guanosine monophosphate synthase inhibitor
pteroic acid synthase inhibitor
1,3-b-d-glucan synthase inhibitor
glucosamine-6-phosphate synthase inhibitor
chorismate synthase inhibitor
atp synthase inhibitor
pantothenate synthase inhibitor
spermidine synthase inhibitor
ceramide synthase inhibitor
prostaglandin d2 synthase inhibitor
acetolactate synthase inhibitor (als)
dehydrosqualene synthase inhibitor (crtm, staphylococcus aureus)
allene oxide synthase inhibitor (cyp-74)
chlorismate synthase inhibitor (ec 4.6.1.4)
enolpyruvateshikamate-3-phosphate synthase inhibitor (epsps)
20-hete synthase inhibitor (hydroxyeicosatetraenoic acid)
inducible nitric oxide synthase inhibitor (inos)
neuronal nitric oxide synthase inhibitor (nnos)
nitric oxide synthase inhibitor (nos, ec 1.14.13.39)
glycogen synthase kinase-3-beta inhibitor (gsk-3beta)
glycogen synthase kinase-a inhibitor (gsk-3a)
fasn-te inhibitor (fatty acid synthase-thioesterase)
inhibitor cell-wall synthesis
acc1 inhibitor (acetyl-coa-carboxylase-1, lipid synthesis)
ps inhibitor (pyrimidine synthesis)
protein synthesis inhibitor
carotenoid synthesis inhibitor
triglyceride synthesis inhibitor
sterol synthesis inhibitor
sphingolipid synthesis inhibitor
metallothionein synthesis inhibitor
dna synthesis inhibitor
cholesterol synthesis inhibitor
siderophore synthesis inhibitor
purine synthesis inhibitor
leucyl t-rna synthesis inhibitor
rna synthesis inhibitor
chitin-synthesis inhibitor
lipid synthesis inhibitor
bleaching agent (pigment synthesis inhibitor)
depigmentor (melanine synthesis inhibitor)
bacterial protein synthesis inhibitor (23s-ribosome)
acetylcholinesterase synthesis inhibitor (ache)
leukotriene b4 synthesis inhibitor (ltb4)
ethylene synthesis inhibitor (ripening delayer)
vlcfa synthesis inhibitor (very long chain fatty acid)
thrs inhibitor (threonyl-t-rna synthetase)
adss inhibitor (adenylosuccinate synthetase, ec 6.3.4.4)
methionyl t-rna synthetase inhibitor
prostaglandin synthetase inhibitor
thymidylate synthetase inhibitor (ec 2.1.1.45)
thromboxane synthetase inhibitor (ec 5.3.99.5)
farnesyl diphosphate synthetase inhibitor (fpps, ec 2.5.1.10)
nad synthetase inhibitor (nicotinamide adenine dinucleotide)
synthetic auxin
a-synuclein aggregation inhibitor
anti-syphilitic
raas inhibitor (renin-angiotensin-aldosterone system)
fungicide (systemic)
insecticide (systemic)
sle treatment (systemic lupus erythematous)
t-butylbicyclophosphorothionate binding inhibitor (tbps)
t-cell proliferation inhibitor
t-type calcium channel blocker
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
anti-viral (polio t1 maheney)
anti-diabetic (type-2, t2dm)
bcr-abl and t315i-mutant kinase inhibitor
thyroxine t4 antagonist
tumor necrosis factor blocker (tnf-a, tace, adam-17)
tachycardic (anti-bradycardic)
tnk-1 antagonist (tachykinin neurotransmitter-1)
tnk2 antagonist (tachykinin neurotransmitter-2)
tnk-3 antagonist (tachykinin neurotransmitter-3)
tnk-3 agonist (tachykinin neurotransmitter-3)
taeniacide (tape worm)
thrombin-activatable fibrinolysis inhibitor (tafia)
nft binder (neurofibriallary tangle)
tnks-1 inhibitior (tankyrase-1)
tnks-2 inhibitor (tankyrase-2)
taeniacide (tape worm)
metacestocide (tape worm)
anti-bacterial (edwardsiella tarda gram+)
neuropathy target esterase inhibitor (nte)
mtor inhibitor (mammalian target of rapamycin)
mtor c1/c2 inhibitor (mamalian target of rapamycin)
anti-viral (hiv, tat)
tau fibrilization inhibitor (polymerization, aggregation)
tau phosphorylation inhibitor
tautomerase inhibitor
anti-neoplastic (taxane refractory)
tsd/sd treatment (tay-sachs, sandhoff diseases)
t-butylbicyclophosphorothionate binding inhibitor (tbps)
b-catenin/tcf4 pathway inhibitor
tdo inhibitor (tryptophan-2,3-dioxygenase, ec 1.13.11.11)
tdp1 inhibitor (tyrosyl-dna phosphodiesterase)
tdp2 inhibitor (tyrosyl-dna-phosphodiesterase-2)
fasn-te inhibitor (fatty acid synthase-thioesterase)
atr inhibitor (ataxia telangiectasia rad3 related)
telomerase inhibitor human (trap assay)
telomerase inhibitor tetrahymena
ftsz inhibition (filimentation temp.-sensitive protein z)
anti-neoplastic (teratocarcinoma)
teratogen (animal)
teratogenic
hsp-90 c-terminal inhibitor
jnk inhibitor (c-jun n-terminal kinase)
jnk-3 inhibitor (c-jun-n-terminal kinase)
terpine (often toxic/irritant)
mutagen (ames test carcinogen suspect)
ames test negative (non-mutagenic)
carcinogenicity tested not positive
microtox tested (toxicity)
anti-neoplastic (testicular)
5-alpha reductase inhibitor (testosterone)
telomerase inhibitor tetrahymena
protozoan super toxicant (tetrahymena spp.)
rna tetraloop binder
transferrin inhibitor (tfr)
transglutaminase-2 inhibitor (tg-2)
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
tgf-b2 inhibitor (transforming growth factor)
tgr-5 agonist (g-protein coupled receptor)
tgt inhibitor (t-rna guanine transglycolase)
th17 inhibitor (t-cell helper)
thalassimia treatment
thalassimia treatment
anti-fungal (botrydiplodia theobrome)
vitamin b2 therapeutic
thermogenic-b3-agonist
thermolysin inhibitor
thermosensation modulator
pkc-theta inhibitor (protein kinase-c)
thiamine-like
fasn-te inhibitor (fatty acid synthase-thioesterase)
thiol protease inhibitor
thioredoxin reductase inhibitor (trxr, ec 1.8.1.9)
thr-b agonist (thyromimetic)
thrs inhibitor (threonyl-t-rna synthetase)
insecticide (thrip)
thrombin-activatable fibrinolysis inhibitor (tafia)
thrombin inhibitor
thrombocytopenia treatment
thrombogenic (platelet aggregant)
cerebral thrombolytic
thrombopoietin agonist
anti-thrombotic
thromboxane a2 agonist
thromboxane a2 antagonist (txa2)
thromboxane antagonist (txra)
thromboxane synthetase inhibitor (ec 5.3.99.5)
thrs inhibitor (threonyl-t-rna synthetase)
thy-x inhibitor (fdts, flavin-dependent thymidylate synthase)
vzv-tk inhibitor (varicella-zoster thymidine kinase)
thymidine kinase inhibitor (ec 2.7.1.21)
mitochondrial thymidine kinase inhibitor (tk-2)
tmpk inhibitor (thymidine monophosphate kinase)
thymidine phosphorylase inhibitor
tmk inhibitor (thymidylate kinase, ec 2.7.4.9)
thy-x inhibitor (fdts, flavin-dependent thymidylate synthase)
thymidylate synthetase inhibitor (ec 2.1.1.45)
thymoleptic (affecting thymus)
thymoleptic (affecting thymus)
thymus stimulant
anti-neoplastic (thyroid)
thyroid coactivator interaction inhibitor
thyroid hormone
thyroid inhibitor
tr-b antagonist (thyroid receptor)
thr-b agonist (thyromimetic)
thyrotropic
thyrotropin-releasing hormone agonist (trh)
thyroxine deiodinase inhibitor
thyroxine t4 antagonist
acaricide (ticks mites)
tissue adhesive
tissue factor vii-a inhibitor
tissue plasminogen activator (tpa)
mitochondrial thymidine kinase inhibitor (tk-2)
vzv-tk inhibitor (varicella-zoster thymidine kinase)
tlr-2 agonist (toll-like receptor)
tlr-4 agonist (toll-like receptor)
tlr-4 inhibitor (toll-like receptor)
tlr-7 agonist (toll-like receptor)
tlr-7 antagonist (toll-like receptor)
tlr-8 agonist (toll-like receptor)
tlr-9 antagonist (toll-like receptor)
tmk inhibitor (thymidylate kinase, ec 2.7.4.9)
tmpk inhibitor (thymidine monophosphate kinase)
tnbc treatment (triple-negative breast cancer)
tumor necrosis factor blocker (tnf-a, tace, adam-17)
tnk-1 antagonist (tachykinin neurotransmitter-1)
tnk-3 agonist (tachykinin neurotransmitter-3)
tnk-3 antagonist (tachykinin neurotransmitter-3)
tnk2 antagonist (tachykinin neurotransmitter-2)
tnks-1 inhibitior (tankyrase-1)
tnks-2 inhibitor (tankyrase-2)
poison (toad/frog)
oxytocin antagonist (tocolytic, delays labor)
drought tolerance promoter
tlr-4 inhibitor (toll-like receptor)
tlr-7 agonist (toll-like receptor)
tlr-7 antagonist (toll-like receptor)
tlr-9 antagonist (toll-like receptor)
tlr-2 agonist (toll-like receptor)
tlr-8 agonist (toll-like receptor)
tlr-4 agonist (toll-like receptor)
pet imaging (positron emission tomography)
cardiac pet imaging (positron emission tomography)
spect imaging (single photon emission computed tomography)
uterotonic (uterus muscle tone)
moleuclar tong
tonic (roborant, restorative)
activity 'cliff' top
anti-microbial topical
anti-septic (topical)
anti-bacterial (topical)
anti-pruritic (topical)
adrenocortical steroid (topical)
fungicide (topical)
vasodilator (topical)
steroid (topical)
protectant (topical)
counter-irritant (topical)
anti-parasitic (topical)
anti-inflammatory (ophthalmic-topical)
disinfectant (topical)
anti-inflammatory (topical)
anesthetic (topical)
anti-neoplastic (topical)
glucocorticoid (topical)
corticosteroid (topical)
topoisomerase i inhibitor
topoisomerase ii inhibitor
topoisomerase iv inhibitor
anti-fungal (candida glabrata, torulopsis)
anti-dyskinetic (giles de la tourette's syndrome)
terpine (often toxic/irritant)
toxic sweetener
mitochondrial toxicant
neuromuscular toxicant
gastrointestinal toxicant
cns toxicant
protozoan super toxicant (tetrahymena spp.)
mock-infected mt4 cell toxicity
microtox tested (toxicity)
reproductive toxicity (ca prop. 65)
reproductive toxicity (ca prop. 65, female)
reproductive toxicity (ca prop. 65, male)
low toxicity to mice or fibroblast cells
toxin
cardio-toxin
cholera toxin inhibitor
toxin, liver
marine toxin/metabolite (algal/sponge/fish)
anti-protozoal (toxoplasma gondii)
tissue plasminogen activator (tpa)
tph-1 inhibitor (tryptophan hydroxylase)
tr-b antagonist (thyroid receptor)
gfr tracer (glomerular filtration rate)
anti-bacterial (trachoma)
tranquilizer (anti-anxiety)
tranquilizer (major)
tranquilizer (minor)
tranquilizer (veterinary)
gaba-t inhibitor (gaba transaminase)
stat-5 inhibitor (signal transducer activator of transcript)
stat-3 inhibitor (signal transducer activator of transcript.3)
anti-viral (hiv, reverse transcriptase)
inhibitor of gene transcription
stat-5 inhibitor (signal transducer activator of transcript)
stat-3 inhibitor (signal transducer activator of transcript.3)
cholesterolester transfer protein inhibitor (cetp)
microsomal triglyceride transfer protein (mtp) inhibitor
garft inhibitor (glycinamide ribonucleotide formyl transferase)
prmt-1 inhibitor (protein arginine methyl-transferase)
atp-prt inhibitor (atp phosphoribosyl transferase)
cpt-1a inhibitor (carnitine palmitoyl transferase)
cpt-1a activator (carnitine palmitoyl transferase)
carm-1 inhibitor (coactivator-assoc. arginine transferase)
icmt inhibitor (isoprenylcysteine carboxyl transferase)
mur-a inhibitor (bacterial transferase)
1nut inhibitor (adenyl transferase)
hmt-dot1l inhibitor (histone methyl transferase)
ppt inhibitor (phosphopantetheinyl transferase)
comt inhibitor (catechol-o-methyl-transferase, ec 2.1.1.6)
lysine methyl-transferase g9a inhibitor
glutathione-s-transferase inducer (gst)
geranylgeranyl transferase inhibitor
peptidyl transferase inhibitor
pyrimidine phosphoribosyl transferase inhibitor
histamine n-methyl-transferase inhibitor
ftase (farnesyl transferase inhibitor)
glutathione-s-transferase inhibitor (gst, ec 2.5.1.18)
n-myristoyl transferase inhibitor (nmt)
phenylethanolamine methyl-transferase inhibitor (pnmt, ec 2.1.1.28)
transferrin inhibitor (tfr)
tgf-b2 inhibitor (transforming growth factor)
tgf-b1 inhibitor (transforming growth factor, alk5 dependent)
aicar transformylase inhibitor
transglutaminase-2 inhibitor (tg-2)
tgt inhibitor (t-rna guanine transglycolase)
trpa1 agonist (transient receptor potential ankyrin)
trpa1 antagonist (transient receptor potential ankyrin)
trpm8 antagonist (transient receptor potential melastatin)
mptp inhibitor (mitochondrial permeability transition pore)
ribosomal translation inhibitor
cap-dependent m-rna translation inhibitor
translation initiation inhibitor
tspo binder (translocator protein)
cftr potentiator (cycstic fibrosis transmembrane conductance regulator)
cftr corrector (cystic fibrosis transmembrane conductance regulator)
cftr blocker (cystic fibrosis transmembrane conductuctance regulator)
hsc transplant enhancer (human stem cell)
treatment renal transplant rejection
glyt-1 inhibitor (glycine transport)
urat-1 inhibitor (uric acid transport)
glut-1 inhibitor (glucose transport)
ut-b inhibitor (urea transport)
kif5b-ret inhibitor (kinase fusion, rearranged during transport)
eaat-1 inhibitor (excitory amino acid transport-1)
eaat-2 inhibitor (excitory amino acid transport-2)
mitochondrial electron transport complex i inhibitor
mitochondrial electron transport complex ii inhibitor
mitochondrial electron transport complex iii (qi) inhibitor
mitochondrial electron transport complex iv inhibitor
fatty acid transport inhibitor
abcb1 transport inhibitor
abcg2 transport inhibitor
nucleoside transport inhibitor
anion transport inhibitor
dopamine transport inhibitor (dat)
noradrenaline/norepinephrine transport inhibitor (net)
polyamine transport inhibitor (pat)
5-ht serotonin transport inhibitor (sert)
anesthetic (transport of fish)
bbb+ actively transported
vacht ligand (vesicular acetylcholine transporter)
huratat-1 inhibitor (human uric acid transporter)
cact inhibitor (carnitine-acylcarnitine transporter)
pcft inhibitor (proton-coupled folate transporter)
asbt inhibitor (apical sodium-dependent bile acid transporter)
abca-1 activator (atp-binding cassette transporter)
ibat inhibitor (ileal bile acid transporter)
vmat-2 inhibitor (vesicular monoamine transporter)
mct-1 blocker (monocarboxylate transporter-1)
sodium-dependent glucose transporter-2 inhibitor (sglt2)
dopamine transporter binder
oatp1-b1 inhibitor (organic anion transporting polypeptide)
oatp1-b3 inhibitor (organic anion transporting polypeptide)
oatp2-b1 inhibitor (organic anion transporting polypeptide)
telomerase inhibitor human (trap assay)
corneal trauma indicator
thyrotropin-releasing hormone agonist (trh)
anti-protozoal (trichomonas)
anti-fungal (trichophyton mentagrophytes)
anti-fungal (trichophyton rubrum)
anti-fungal (trichophyton spp., ringworm, jock-itch)
triglyceride synthesis inhibitor
microsomal triglyceride transfer protein (mtp) inhibitor
tripeptidyl peptidase 2 inhibitor
dutp inhibitor (deoxyuridine triphosphatase)
guanosine triphosphatase inhibitor (gtp-ase)
ip3 inositol triphosphate agonist
tnbc treatment (triple-negative breast cancer)
triple reuptake inhibitor (serotonin, norepinephrine, dopamine)
triterpene natural product
trk-a inhibitor (tropomyosin-related kinase)
trk-b agonist (tyrosine kinase)
trk-b inhibitor (tropomyocin-related kinase)
trmd inhibitor (t-rna-n1-g37 methyltransferase)
anti-fungal (candida tropicalis)
trk-b inhibitor (tropomyocin-related kinase)
trk-a inhibitor (tropomyosin-related kinase)
trpa1 agonist (transient receptor potential ankyrin)
trpa1 antagonist (transient receptor potential ankyrin)
trpm8 antagonist (transient receptor potential melastatin)
vanilloid agonist (trpv1)
vanilloid antagonist (trpv1)
trpv2 agonist (vanilloid)
trpv3 agonist (vanilloid)
trpv3 antagonist (vanilloid)
vanilloid agonist (trvp4)
thioredoxin reductase inhibitor (trxr, ec 1.8.1.9)
try-r inhibitor (trypanothione reductase)
anti-protozoal (trypanosoma)
anti-protozoal (trypanosoma cruzi or t.brucei, chagas, sleeping sickness)
try-r inhibitor (trypanothione reductase)
human pancreatic trypsin inhibitor
trypsin inhibitor
b-tryptase inhibitor
tdo inhibitor (tryptophan-2,3-dioxygenase, ec 1.13.11.11)
tph-1 inhibitor (tryptophan hydroxylase)
tsd/sd treatment (tay-sachs, sandhoff diseases)
anti-prion (tse, cjd, scrapie, misfolded protein)
tspo binder (translocator protein)
mps-1 inhibitor (monopolar spindle, ttk)
amyloidosis treatment (ttr, sodi, or p53)
anti-bacterial (mycobacterium tuberculosis)
anti-bacterial (tuberculosis,dormant,non-replicating)
anti-bacterial (mycobacterium tuberculosis, mdr)
tuberculostatic
microtubule stabilizer (binder, tubulin inhibitor)
tubulin polymerization inhibitor
anti-bacterial (francisella tularensis, bio-warfare agt.)
anoikis (tumor adhesion reducer)
tumor necrosis factor blocker (tnf-a, tace, adam-17)
tumorogenic or tumor promoter
tumorogenic or tumor promoter
anti-neoplastic (chemo-induced tumors)
anti-neoplastic (solid tumors)
insecticide (turf)
turf growth regulator (grass)
beta turn mimetic
anti-tussive
k2p potassium channel modulator (twin pore)
prrb-prra two-component histidine kinase
thromboxane a2 antagonist (txa2)
thromboxane antagonist (txra)
tyk-2 inhibitor (tyrosine kinase)
calcium channel blocker (l-type)
anti-diabetic (type-2, t2dm)
l-type calcium channel blocker
t-type calcium channel blocker
n-type voltage gated calcium channel blocker (vgcc, vdcc)
anti-bacterial (salmonella typhi gram-ve)
anti-tyrosinaemia
tyrosinase inhibitor (rtk, ec 1.14.18.1)
tyrosine hydroxylase inhibitor
lck sh2 inhibitor (lymphocyte-specific protein tyrosine kinase)
flt-3 inhibitor (tyrosine kinase)
tyk-2 inhibitor (tyrosine kinase)
syk inhibitor (spleen tyrosine kinase)
irtk activator (insulin receptor tyrosine kinase)
c-kit inhibitor (cd 117, tyrosine kinase)
dyrk-1a inhibitor (dual-specificity tyrosine kinase)
pyk2 inhibitor (proline-rich tyrosine kinase)
mer-rtk inhibitor (receptor tyrosine kinase)
trk-b agonist (tyrosine kinase)
tyrosine kinase-a inhibitor
btk inhibitor (bruton's tyrosine kinase, beta cells)
erb-tyrosine kinase inhibitor
c-src tyrosine kinase inhibitor
cmet tyrosine kinase inhibitor
protein tyrosine kinase inhibitor (ptk)
dyrk-1b (dual-specificity tyrosine kinase, mirk)
lmw-ptp inhibitor (low mw protein tyrosine phosphatase)
mptp-b inhibitor (microbacterium tyrosine phosphatase)
ptp-1b inhibitor (protein tyrosine phosphatase)
ptpn-22 inhibitor (lymphoid tyrosine phosphatase, lyp)
ptp-shp2 inhibitor (protein tyrosine phosphatase-src)
tdp1 inhibitor (tyrosyl-dna phosphodiesterase)
tdp2 inhibitor (tyrosyl-dna-phosphodiesterase-2)
u1061-a rna binder
usp1/uaf1 inhibitor (ubiquitin-specific protease)
ubiquitin conjugation inhibitor (e1/e2)
ubiquitin conjugation inhibitor (e3)
fraxin/ubiquitin interaction inhibition
usp1/uaf1 inhibitor (ubiquitin-specific protease)
uch-l1 inhibitor (ubiquitin-specific protease)
uch-l1 inhibitor (ubiquitin-specific protease)
mur-b inhibitor (udp-ep-glu-nac reductase)
udp-galactose-4'-epimerase (ec 5.1.3.2)
ul-97 kinase inhibitor
anti-ulcer
analgesic (ulcer)
anti-ulcerative colitis
ultraviolet screen (sunscreen)
oxidative phosphorylation uncoupler
upps inhibitor (undecaprenyl diphosphate synthase)
photo-unstable
urokinase plasminogen activator (upa)
upa inhibitor (urokinase plasminogen activator)
anti-upper intestinal disorders
upps inhibitor (undecaprenyl diphosphate synthase)
apo-a1 upregulator
mediates uptake blood to liver (hepatocytes)
anandamide uptake inhibitor
5-ht serotonin uptake inhibitor
5-htp serotonin uptake inhibitor
pzu antagonist (protamine zinc uracil)
urat-1 inhibitor (uric acid transport)
ut-b inhibitor (urea transport)
urease inhibitor
uricosuric (uric acid excretor, gout treatment)
urat-1 inhibitor (uric acid transport)
huratat-1 inhibitor (human uric acid transporter)
uricosuric (uric acid excretor, gout treatment)
uridine phosphorylase inhibitor
anti-bacterial (urinary)
analgesic (urinary)
anti-septic (urinary)
urinary acidifier
urinary acidifier (veterinary)
urinary incontinence (dysuria, overactive bladder, oab)
urokinase inhibitor
upa inhibitor (urokinase plasminogen activator)
urokinase plasminogen activator (upa)
anti-urolithic
urotensin-2 agonist
urotensin ii antagonist
usp1/uaf1 inhibitor (ubiquitin-specific protease)
ut-b inhibitor (urea transport)
anti-neoplastic (hela cervical uterine endometrial)
uterine relaxant
uterotonic (uterus muscle tone)
uterotonic (uterus muscle tone)
vasopressin v1a antagonist
vasopressin v1b antagonist
vasopressin v2 agonist
vasopressin v2 antagonist (avpr2)
vaccine adjuvant
anti-viral orthopox (vaccinia/cow, smallpox)
vacht ligand (vesicular acetylcholine transporter)
atp-ase inhibitor (incl. vacuolar, v-atp-ase)
vaginal disinfectant
p97 inhibitor (vcp, valosine containing protein)
anti-bacterial (enterococcus casselflavus gram-, vancomycin resistant)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
trpv2 agonist (vanilloid)
trpv3 antagonist (vanilloid)
trpv3 agonist (vanilloid)
vanilloid agonist (trpv1)
vanilloid agonist (trvp4)
vanilloid antagonist (trpv1)
vap-1 inhibitor (vascular adhesion protein)
vzv-tk inhibitor (varicella-zoster thymidine kinase)
vap-1 inhibitor (vascular adhesion protein)
vcam-1 inhibitor (vascular cell adhesion molecule)
anti-cerebral vascular disease
anti-vascular disorders
vda vascular disruptive agent
vegf-3 inhibitor (vascular endothelial)
vegf-2 inhibitor (vascular endothelial g.f., kdr, fr)
vasoconstrictor (vasopressor, anti-hypotensive)
vasodilator
vasodilator (cerebral)
vasodilator (coronary)
vasodilator (nasal)
vasodilator (peripheral)
vasodilator (renal)
vasodilator (topical)
vasopeptidase inhibitor
vasopressin v1a antagonist
vasopressin v1b antagonist
vasopressin v2 agonist
vasopressin v2 antagonist (avpr2)
vasoconstrictor (vasopressor, anti-hypotensive)
vasoprotectant
vcam-1 inhibitor (vascular cell adhesion molecule)
p97 inhibitor (vcp, valosine containing protein)
vda vascular disruptive agent
n-type voltage gated calcium channel blocker (vgcc, vdcc)
cbi-vdr (coactivator binding inhibitor vitamin d)
anti-bacterial (salmonella typhi gram-ve)
gene delivery vector
fruit & vegetable setting agent
vegf-2 inhibitor (vascular endothelial g.f., kdr, fr)
vegf-3 inhibitor (vascular endothelial)
anti-venous disorders
anti-arrhythmic (ventricular)
anti-vertigo
vesicant
vacht ligand (vesicular acetylcholine transporter)
vmat-2 inhibitor (vesicular monoamine transporter)
anti-bacterial (veterinary)
sedative (veterinary)
insecticide (veterinary)
anti-protozoal (veterinary)
muscle relaxant (veterinary)
food additive (veterinary)
vulnerary (veterinary)
urinary acidifier (veterinary)
tranquilizer (veterinary)
abortifacient (veterinary)
progestin (veterinary)
phosphorus source (veterinary)
parasiticide (veterinary)
flukicide (veterinary)
anaplasmodastat (veterinary)
ectoparasiticide (veterinary)
cns stimulant (veterinary)
anthelmintic (veterinary)
appetite stimulant (veterinary)
anti-spasmodic (veterinary)
anti-microbial (veterinary)
anti-inflammatory (veterinary)
anesthetic (veterinary)
anti-plasmodial (veterinary)
analgesic (veterinary)
anabolic (veterinary)
glycosuric (veterinary)
n-type voltage gated calcium channel blocker (vgcc, vdcc)
voltage gated sodium channel blocker (vgsc)
tissue factor vii-a inhibitor
cfviia inhibitor (coagulation factor viia)
anti-viral
anti-dna viral
anti-viral (bvdv, hcp)
bv-ca inhibitor (hepatitis b viral capsid assembly)
anti-viral (cmv, herpes-2 cytomegalo)
anti-viral (coxsackie)
anti-viral (flavivirus, dengue, west nile)
viral helicase inhibitor
anti-viral (hepatitis)
anti-viral (hepatitis c, hcv)
anti-viral (herpes genitalis)
anti-viral (hiv)
anti-viral (hiv, attachment/ entry inhibitor)
anti-viral (hiv, reverse transcriptase)
anti-viral (hiv, tat)
anti-viral (hsv-1 herpes simplex)
anti-viral (hsv-1 & hsv-2)
anti-viral (human rhinovirus)
anti-viral (influenza)
anti-viral measles (paramyxovirus)
anti-viral (neurotropic, alpha)
anti-viral (ophthalmic)
anti-viral orthopox (vaccinia/cow, smallpox)
anti-viral (polio t1 maheney)
hbvp inhibitor (hepatitis-b viral polymerase)
anti-viral (poultry)
rsv anti-viral (respiratory syncytial fusion)
anti-viral (rous sarcoma)
anti-viral (rubella)
anti-viral (sars-corona)
anti-viral (vzv, pox)
anti-viral (warts)
anti-viral (west nile)
virulence signaling inhibitor
anti-hpv (human papilloma virus)
chikv inhibitor (chikungunya virus)
ebi-2 antagonist (epstein-barr virus-induced)
hematopoietic vitamin
vitamin
nutrition aid: vitamin b deficiency
vitamin b1 source
vitamin b2 therapeutic
pro-vitamin d
cbi-vdr (coactivator binding inhibitor vitamin d)
vitamin d activity
vitamin e
vitamin k
vitronectin antagonist (a5b3)
anti-plasmodium (vivax)
vla4 antagonist (very late antigen, eosinophil integrin)
vlcfa synthesis inhibitor (very long chain fatty acid)
vmat-2 inhibitor (vesicular monoamine transporter)
kca1.1 potassium channel opener (ca and voltage gated)
n-type voltage gated calcium channel blocker (vgcc, vdcc)
voltage gated sodium channel blocker (vgsc)
high volume industrial chem. epa (450,000 kg/yr)
pi-3kc inhibitor (phosphoinositide kinase) (vps-34)
anti-bacterial (vancomycin-resistant enterococcus faecalis, vre)
vulnerary (cicatrizant, wound healer)
vulnerary (veterinary)
anti-viral (vzv, pox)
vzv-tk inhibitor (varicella-zoster thymidine kinase)
anti-neoplastic (walker 256)
inhibitor cell-wall synthesis
chemical warfare agent
anti-bacterial (francisella tularensis, bio-warfare agt.)
anti-viral (warts)
poison (hemlock water dropwort)
negative inotrope (weakens muscle contraction)
anti-asthenia (weakness)
anti-viral (west nile)
anti-viral (flavivirus, dengue, west nile)
anti-enuresis (bed-wetting)
anti-fungal (wheat rust)
anti-wilson's disease
anti-autistic (social withdrawal)
discontinued (withdrawn)
wnt inhibition (porcn)
wood preservative
ovarian inhibitor (worker bees)
insecticide (spodoptura eridania, southern army worm)
taeniacide (tape worm)
metacestocide (tape worm)
filaricide (worms)
vulnerary (cicatrizant, wound healer)
ccxr1 antagonist (chemokine-x1)
mrg-x1 antagonist (mas-related genes)
xanthine oxidase inhibitor
xeroderma pigmentosum-g (xpg)
anti-xerophthalmic
anti-xerostomia (dry mouth)
factor xia antagonist (fxia)
xiap antagonist (x-linked inhibitor apoptosis protein)
bcl-xl inhibitor (anti-apoptotic protein)
xeroderma pigmentosum-g (xpg)
npy-1 antagonist (neuropeptide-y1)
npy-5 antagonist (neuropeptide-y5)
yaws treatment
yoph inhibitor (yersinia outer protein phosphatase)
anti-bacterial (yersinia pestis)
anti-plasmodial (yoelii)
yoph inhibitor (yersinia outer protein phosphatase)
high volume industrial chem. epa (450,000 kg/yr)
ezh-2 inhibitor (enhancer zeste homolog)
pkcz inhibitor (protein kinase-c zeta)
lpx-c inhibitor (zinc-dependent acetylase)
pzu antagonist (protamine zinc uracil)
dlk,map3k12 inhibitor (dual leucine zippper kinase)
vzv-tk inhibitor (varicella-zoster thymidine kinase)